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The EU's Foreign Policy - Limits of Conditionality - the Case of EU-Cuban Relationship in 1996-2008
Radačičová, Simone ; Perottino, Michel (advisor) ; Bartovic, Vladimír (referee)
The Master thesis deals with the analysis of the concept of conditionality that is applied in European Union's external relations with Cuba. The theoretical background determinates the conditions that can influence the efficiency of conditionality when applied to the developing countries. The relationship between Cuba and the EU is based on the Common position which was agreed in 1996. It set conditions that Cuba has to fulfill in order to normalize its links with the EU. In the 90s, EU used the positive conditionality with mixed results, but following the events of the spring 2003, the EU member states agreed on a tougher stance, i.e. the adoption of diplomatic measures, in fact the negative conditionality. This approach brought a couple of negative effects and challenged the EU's influence on Cuban politics. Following the review the EU member states suspended the sanctions and in 2008 abolished the remaining diplomatic measures. Despite of its limits, the conditionality applied in the framework of realistic policy remains to be an important element in the relations between EU and Cuba. Powered by TCPDF (www.tcpdf.org)
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Characterization of plasma during organosilicone thin film deposition using haxamethyldisiloxane monomer
Blahová, Lucie ; Mazánková, Věra (referee) ; Krčma, František (advisor)
The aim of this thesis is plasma diagnostic during deposition of thin films based on organosilicones. Hexamethyldisiloxane was used as a precursor for plasma deposition in the presence of oxygen, and the diagnosis was performed by using optical emission spectroscopy. The theoretical part summarizes the basic characteristics of plasma and processes occurred at plasma polymerization and deposition. It also deals with thin films and their use in coating materials. A relatively large part is devoted to the specification of the physical-chemical nature of the used analytical method – optical emission spectroscopy. Finally, the principles of rotational, vibrational and electron temperature calculations are described. The contemporary deposition process was carried out in continuous and pulsed mode of radiofrequently excited capacitively coupled discharge. The effects of monomer flow rate, plasma power and duty cycle on the deposition process were studied. In the individual spectra, atomic hydrogen lines of Balmer’s series as well as an atomic oxygen line were identified. Molecular bands of CO have been identified as Angstrom’s system and 3. positive system. In the case of the identified fragments, the intensity dependencies on the monomer concentration in mixture, plasma power and duty cycle were detected. Electron temperature of plasma was also calculated using the relative intensities of atomic hydrogen lines of Balmer’s series. Vibrational and rotational temperature could not have been determined because no suitable fragments for their determination were found in the spectrum. Based on findings mentioned above, partial composition of plasma and some of its properties were estimated. The subject of the further research will be determination of the exact content and structure of the thin films and investigation of other plasma characteristics. Plasma deposition is influenced by many factors, and the study of their optimal combination for the most efficient deposition process is a goal for the future research.
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Fed's Easy Money Policy during Alan Greenspan's presidency in Board of Governors (1987-2006)
Mašek, František ; Johnson, Zdenka (advisor) ; Tajovský, Ladislav (referee)
The main theme of the work is the Fed's monetary policy during the time, when chairman of the Board of Governors was Alan Greenspan. The greatest attention is aimed at the influence of Fed's expansive monetary policy on the so-called dot-com bubble and later mortgage crisis, which subsequently developer into the financial crisis. Through a thorough analysis of many scientific papers written by known economists and my own analysis and evalution I opine that the effect of expansionary monetary policy on the bubble in technological assets and mortgage crisis is rather minor. Fed subordinated all actions to achieve its monetary policy objectives, so criticism of its conducted monetary policy is essentially a critique of these objectives as such. I consider the emergence of new technologies and the so-called theory of feedback as the main cause of dot-com bubble. In the mortgage crisis and subsequent financial crisis as main determinants I consider reluctance of goverment officials strongly regulate activities of investment banks and other investment companies, moral hazard, failure of rating agencies, and federal support for home ownership coupled with the deregulation of the financial sector.
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Study of Transport Mechanisms of Receptor-Specific Radiopharmaceuticals in the Kidney Cells.
Cihlo, Jan ; Lázníček, Milan (advisor) ; Šimůnek, Tomáš (referee) ; Komárek, Pavel (referee)
Renal accumulation of radiolabelled receptor specific substances can represent clinical problems for diagnosis and therapy of some typical malignancies due to radionephrotoxicity of these substances. The aim of this work was to design a suitable in vitro model for evaluating cumulative disposals of studied radiopharmaceuticals in the kidney and for finding possible mechanisms reducing the reabsorption of these substances by renal tubular cells. The suggested model designed for this purpose provides another opportunity for evaluation of their radionephrotoxical potential. The aforementioned in vitro method was standardised and used for the study of transport mechanism of some representatives of radiolabelled somatostatin analogues (111In/125I/90Y/177Lu-DOTA-Tyr3-octreotate, 111In/90Y/177Lu-DOTA-1-Nal3-octreotide), antibodies (111In/90Y/99mTc-AntiCD66) and albumin (FITC-albumin, 99mTc-albumin). All studied radioactive substances were radiolabelled with good practice and analyzed using HPLC and/or ITLC-SG methods. The radiolabelling technique of all studied specifically acting substances (radiolabelled peptides and antibodies) and also any concrete radionuclide showed no significant influence over the internalization into the renal OK cells. The difference of the internalized amount of FITC-albumin and...
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The Parents of Handicaped Child
ČAPKOVÁ, Daniela
The present bachelor thesis focuses on unusualness of life and experience of parents who have a handicapped child. The aim of this study is to investigate how the handicap of their child influences, limits or contributes to their life. For this purpose, the focus lies on the impact of this situation on the family relationships, alternatively relationship to themselves. The theoretical part examines tasks connected with middle adulthood, I also define the role of parent, furthermore I am focused on a specific load which is connected with handicap of child. The empirical part is based on qualitative research applying semi-structured interviews. The current study consisted of six samples, which were based on interviews with six volunteers three parental couples. Interviews were conducted with one parental couple together at the same time, withpartner´s presence. It was assumed that respondents could fill in the partner´s statement and providing an emotional support of a partner was another purpose. As expected, differences were found between the attitude of mothers and fathers of their life situation.
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Liver gangliosides in cholestasis induced by bile duct ligation.
Hynková, Barbora ; Entlicher, Gustav (advisor) ; Ledvinová, Jana (referee)
Gangliosides are sialic acid-containing glycosphingolipids located on the cell surface of all animal cell types. They play a role as receptor molecules, share in cell-to-cell interaction and protect the cell against harmful environmental factors by increasing of rigidity of cell surface. This diploma thesis studies an influence of experimental cholestasis on hepatic ganglioside composition. Cholestasis was induced by bile duct ligation in Wistar rats. A significant increase of total lipid bound sialic acid and b-series gangliosides (GD1b, GT1b, event. GD3) was found in cholestatic liver when compared with controls. These results found in obstructive cholestasis correspond with the results Majer et al. Biomed. Chromatogr., 21, 446-450 (2007), described in 17α− ethinylestradiol induced cholestasis, but the increase of b-series gangliosides was milder in our study. As a second point, an effect of modulated heme-oxygenase 1 (HO-1) activity was investigated in cholestatis induced bile duct ligation (HO-1 activator- hemine, HO-1 inhibitor- Sn-mesoporphyrin). An increase of a total lipid sialic acid was found in Sn-mesoporphyrin treated animals, but a decrease of some a- and b- series gangliosides was observed. In group with activated HO-1 total sialic acid increased, but the composition of gangliosides...
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Coeliac disease and its impact in the life of a child at younger school-age.
MIKEŠOVÁ, Annemarie
Celiac sprue or celiac disease leads to a lifelong adherence to the diet, i.e. to a total exclusion of gluten from the diet. In celiac disease antibodies are released, that act autoimmune and affect the inherent small intestinal tissue, while the detachment of antibodies is caused by the presence of gluten in food. In pathological process the disorder of the morphology of small intestinal walls occurs, causing the reduction of intestinal villus height, which are physiologically present on every intestinal mucosa. In a critical state the subtotal or total atrophy of intestinal villi rises means their partial or complete disappearance. This damage of mucosa results in chronic inflammatory processes, which cause malabsorption.Celiac sprue is a chronic, autoimmune disease developing either on genetic background or due to the immune response.The basic and only treatment consist in longlife exclusion of gluten from the diet., i.e. the suppression of toxic protein occurring in cereal grain. Celiac sprue belongs to the incurable diseases and preventing the complications, which may occur in relation to a bad regime, is a matter of course. Nowadays the importance is attached to prevention, which is divided into three basic levels: primary, secondary and tertiary. The primary prevention is crucial, it is when the incidence of the disease is sought out. The time, when the gluten gets into the child´s body for the first time, has a great influence on the development of the disease. The main goal of this thesis was to map the issue of celiac disease of early-school-age children with a focus on the specifics of nursing using the literature available. The celiac disease issue was searched out in bibliographic publications and on the Internet. Based on the stated objective, the synthesis method, explanation or data demonstration was chosen for this bachelor thesis. Economic point of view is regarded as a fundamental issue of the disease. It turned out that only a small number of czech health insurance companies provides a catering allowance to celiac patients. It was found out, that in many EU states so called community care provided by community nurse, exists. There is no trend like this in Czech republic despite the fact, that this field can be studied in the master study. The nurse is an unsubstitutable member and fundamental pillar of a multidisciplinary team. She also has significant competencies in patient care and constitutes an irreplaceable place in nursing. The output of this theoretical thesis is to create a comprehensive view of the range of problems related to celiac disease of early-school-age children.
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On-chip and capillary electrophoresis for cancer research
Hájková, Tereza ; Babula, Petr (referee) ; Provazník, Ivo (advisor)
The thesis deals with cancer disease and its genesis. The prostate cancer is the second most dangerous disease in male population. It is very important to detect it in early stage. This thesis deals with the proteins which are or could be used as potential cancer markers. For example in current commonly used the prostate-specific antigen and newly the metallothionein. Metallothionein is a protein occuring in fauna and flora in four basic isoforms. There is a hypothesis that the isoform content or/and their ratio may have a diagnostic implication and could be used in clinical practise. For this reason they are studied and developed methods for specific and sensitive analysis of individual isoforms. In this work, capillary electrophoresis is used for the separation of the isoforms. The influence of the parameters such as type of background electrolyte, its pH and separation voltage etc. on the final separation are discussed.
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