National Repository of Grey Literature 901 records found  1 - 10nextend  jump to record: Search took 0.21 seconds. 

Functions of central bank in hand Czech Republic on receipt of Euro
TRUHLÁŘOVÁ, Dagmar
The bachelor thesis is dealing with the role of the central bank in the preparation for the acceptance of new currency - Euro currency. The goal of my thesis is the analysis of change in competences and functions of the central bank, especially changes concerning the bank industry, companies as well as ordinary people. The next aim of my thesis is the description of new functions, advantages and disadvantages of the acceptance Euro currency and I am also dealing with the binding of the currency transfer and the inflation.

Aspects of the Pastoral Care in the Pauline Congregations
Ravasz, Hajnalka ; Pokorný, Petr (advisor) ; Theißen, Gerd (referee) ; Luz, Ulrich (referee)
The thesis "Aspects of the Pastoral Care in the Pauline Congregations" presents some aspects of the praxis of pastoral care in the graeco-roman Antiquity and in the New Testament how it is principally revealed in the 1st Thessalonians. The main chapters of the thesis expose the chosen aspects of pastoral care like the function of imitation and examples, the role of the pastor in the pastoral act, the process of comforting or the caring congregations. But the research does not end with the comparison of the antic psychologic tradition with the Pauline practise; at least one modern social-psychological method is introduced in every chapter and they are used as a help for a different and sometimes maybe astonishing re-reading of the well-known Bible texts. The social connections analyzing social psychology helps the New Testament finding new methods and language to express the caring interactions between Paul and his congregations. This interdisciplinary thesis aims after binding the biblical texts with their contemporary context and the modern social psychology to reach a helping hand for the practical theology, mainly for pastoral care drawing the conclusion from the exegesis for our eneryday practise. Powered by TCPDF (www.tcpdf.org)

Ultrasonographic evaluation of cardiovascular abnormalities in patients with Fabry disease
Paleček, Tomáš ; Bultas, Jan (advisor) ; Pudil, Radek (referee) ; Kittnar, Otomar (referee)
Fabry disease is an X-linked glycosphingolipid storage disorder caused by deficient activity of the lysosomal enzyme α-galactosidase A. This leads to progressive intracellular accumulation of neutral glycosphingolipids, mainly globotriaosylceramide. Besides various extracardiac disease-related abnormalities, cardiovascular involvement represents a typical manifestation of Fabry disease. The primary underlying mechanism relies on pathological substrate accumulation in cardiomyocytes, conduction system cells, valvular fibroblasts, endothelial cells and vascular smooth muscle cells. The development of cardiac and vascular hypertrophy represents a characteristic cardiovascular feature of Fabry disease. The aim of our studies was to describe in detail cardiovascular abnormalities in patients with Fabry disease using ultrasonography, which currently represents basic noninvasive imaging modality in cardiology. We focused on structural and functional abnormalities of ventricles, valvular apparatus and their relationship to vascular involvement expressed on common carotid arteries. We also compared the diagnostic accuracy of the two novel echocardiographic methods used for the left ventricular diastolic function assessment. The possible existence of circulating proliferative factor, which might be associated with...

Molecular factors of artherogenesis in chronic kidney disease with experimental model of chronic inhibition of Nitric Oxide Synthesis and its Effect of HMG-CoA reductase inhibitoin
Lecian, Dalibor ; Matouš, Bohuslav (advisor) ; Tesař, Vladimír (referee) ; Zadražil, Josef (referee)
The experimental part of the thesis covered the markers involved in nitric oxide deficiency model in rats. The analogue of arginine N-nitro- L -arginine-methyl ester ( L -NAME) was used. L -NAME administration resulted in sustained elevation of BP, decreased GFR, and in higher albuminuria compared to control animals. The administration of hypolipidemic drug - atorvastatin to Wistar rats was studied. The statin used caused lower albuminuria and prevented decreases in GFR in L -NAME rats without having an impact on hypertension. CAV1 protein expression was similar in all groups of rats. In contrast, VEGF expression and RhoA activity was increased in L -NAME-treated animals, and normalized with coadministration of atorvastatin. Clinical part of the thesis focused on the analysis of markers of oxidative stress in obese and non-obese patients with CKD and after kidney transplantation. The patients with CKD had elevated serum concentrations of AGEs, sRAGE and ADMA with the maximal concentrations of AGEs in the patients on hemodialysis. The successful kidney transplantation decreases the AGEs, sRAGE and ADMA concentrations but not to normal value according to general population. Patients with obesity exhibited lower concentrations of sRAGE in CKD as a protective factor for cardiovascular disease. Concentrations of...

Selected psychological connections of changes in teachers' profession and their profesional preparation
Štětovská, Iva ; Gillernová, Ilona (advisor) ; Vališová, Alena (referee) ; Dobrovská, Dana (referee)
The thesis introduces a rather unusual continual discussion concerning the context of social changes and their impact on school life, pre-gradual preparation, and professional achievement of teachers. The text surveys the connectedness between recent social changes and the development of professional institutions, especially schools. The author considers gradual weakening of primarily educational function of schools and their shift of social responsibility toward educative and socializing commitments. As a consequence of such changes special attention is paid to current teachers' position and modifications of their professional activities. The author attempts to state new teachers' competences and highlights of their work. She asks what new demands can be observed in the course of teachers' professional preparation. Regarding the key position of relationships at current schools, the text focuses on communication patterns at school, which are fulfilled via relationships. The author discusses social support problems in details as they represent a crucial factor of teachers' work. The text introduces various approaches to a safe feedback to teachers. Particular examples include methods of video- interaction guidance and Balint groups applied to teachers' work. Regarding psychological applications and the...

Relationship of C-reactive protein and copper concentration as a laboratory markers of inflammation to the clinical and prognostic indicators in patients with chronic heart failure of ischemic etiology
Málek, Filip ; Špaček, Rudolf (advisor) ; Špinarová, Lenka (referee) ; Hradec, Jaromír (referee) ; Horký, Karel (referee)
In patients with chronic heart failure of ischemic etiology and systolic left ventricular dysfunction was evaluated significance of determination of concentrations of acute phase proteins and serum concentrations of copper. Showed statistically significant correlation between the concentration of C-reactive protein and parameters of cardiac function. Our work found a significant inverse relationship between CRP concentration and left ventricular ejection fraction and a significant positive correlation of CRP concentration on the degree of diastolic left ventricular dysfunction. It was also found statistically significant correlation between the concentration of acute phase proteins C-reactive protein, fibrinogen and serum concentrations of copper. It was also further demonstrated the relationship of serum concentrations of copper to the degree of cardiac insufficiency and significant correlation between serum copper concentration to the resting heart rate.

The endocrine function of adipose tissue and its importance for initiation and development of insulin resistance and diabetes
Haluzík, Michal ; Schreiber, Vratislav (advisor) ; Marešová, Dana (referee) ; Šeda, Ondřej (referee)
Endocrine production of adipose tissue is a very complex process affected by numerous endogenous and exogenous stimuli. Peroxisome proliferator-activated receptors-alpha (PPAR-) are important modulators of metabolic processes which can also affect endocrine function of adipose tissue. Recently, numerous novel factors produced by adipose tissue with important metabolic effects were identified. Some of them can directly bind PPAR receptors. One of the examples of these factors is fatty acid binding protein 4 (FABP4) which can directly bind PPAR receptors and indirectly modify its activation by changing availability of endogenous PPAR ligands -free fatty acids. We hypothesized that the mechanism of action of PPAR receptors to metabolic processes may partially lie in their complex interaction with adipose tissue-derived hormones. The unraveling of these interactions may have important consequences in finding approaches to treat patients with type 2 diabetes mellitus. (...) In summary, our data show an important role for the interplay of PPAR activation and endocrine function of adipose tissue in metabolic regulations which may have important clinical consequences.

Development of physiological posture and motion in a pre-school period - function of hand
Stachelová, Dagmar ; Zounková, Irena (advisor) ; Jelínková, Barbora (referee)
This study is focused on problems of developing handskills of children at pre-school age. Reaching, voluntary grasp, carry, voluntary release, bilateral hand use and tool-skills are described here, according to their age clasification. I refer to interrelationships between handskills and musculosceletary, visual, motoric, somatosensoric, perceptional, and cognitive system. I also mention method of examination of grasp and its therapy via special physiotherapeutic concepts and methods. Powered by TCPDF (www.tcpdf.org)

Přístroj pro měření koncentračních profilů – Analýza výstupních dat
Čermák, Jiří ; Stloukal, Ivo
In this paper, a new modification of a commercial apparatus Edwards Coating system E306A is described that enables to perform diffusion measurements with radioactive tracers. The plan-parallel thin layers are removed by sputtering with Ar+ ions and the well defined fraction of the sputtered-off material is sequentially collected. The function of the apparatus is exemplified by the measurement of bulk diffusion coefficient of 65Zn in Fe40Ni40B20 alloy at T = 684 K.

Assessment of service conditions of the screw grips of testing machine MTS 810
Votroubek, Tomáš ; Čermák, Jan (referee) ; Náhlík, Luboš (advisor)
This diploma thesis is aimed to assessment of safety of screw grips of testing machine MTS 810. Some parts of grips are predisposed to damage at low temperature (-180°C), e.g. spacer, isolating ceramics lamellas, etc. To guarantee its perfect function under hard laboratory conditions the finite element analysis was performed and suitable modifications grips parts have been suggested with respect to maximum of application of recent parts. Part of the thesis is devoted to suggestion of suitable tightening torque of experimental sample under different temperatures. For necessary numerical computations FEM system Ansys was used.