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Accuracy Check of Levelling Systems
Szabó, Tibor ; Bárta, Ladislav (referee) ; Bureš, Jiří (advisor)
The bachelor thesis was concerned with checking the accuracy of the robotic total station with automatic targeting on the metrological calibration base FAST. The first part of the thesis deals with the explanation of basic concepts of height measurement, describes geodetic methods of height measurement and current solution of the problem. The main part of the work is devoted to the control of the used apparatus and the equipment, describes the calibration bases, methods of measurement and processing of the measured data. The resulting accuracy and differences were compiled into tables and graphs.
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Verification of basic parameters of complete blood count using analyser Sysmex XT 4000i, result comparison of patients' samples with analyser Sysmex XT 2000i in accredited laboratory.
MOUČKOVÁ, Lenka
Central Laboratories of Strakonice Hospital, joint stock company, are accredited according to CSN EN ISO 15189 Medical laboratories - Particular requirements of quality and competence. Requirements of verification and validation of methods emerge from this accreditation. Results of validation and verification processes are used to evaluate the uncertainty of measurement and assessment for continuity and comparability of measurement results. Introduction of a new type of automated hematology analyzer Sysmex XT-4000i in Central laboratories in Strakonice Hospital, joint stock company, in the hematology and blood storage section, requires verification and validation of basic examined blood count parameters on hematology analyzer Sysmex XT-4000i.The theme of the work is based on the requirements of CSN EN ISO 15189 and SOPO-C-06 Method validation/verification procedure for introducing laboratory hematology analyzer. Measurements of the basic parameters of blood count , namely leukocytes, erythrocytes, platelets, hemoglobin, hematocrit and mean corpuscular volume were done according to this document. Measurements of these parameters were used to evaluate a precision in terms of repeatability, precision in terms of reproducibility and accuracy. Parameters leukocytes, erythrocytes, platelets, hemoglobin, hematocrit and mean corpuscular volume were measured from twenty patient samples at two concentration levels to evaluate the precision in terms of repeatability. Basic parametres of blood count validated in EHK process were measured to evaluate the precision in terms of reproducibility. Reference materials e-check level 1 and e-check level 2 from Sysmex manufacturer were used as hematology control materials which moved within the physiological range. Measurements of these two reference materials were carried out daily during 20 days in a singlet. These measurements were used as the basis to calculate basic statistical parameters, the variational coefficient of repeatability and the variational coefficient of reproducibility from which variational analytical coefficient was calculated. The variational coefficient of reproducibility was used to compare methods of investigated parameters to the data specified by the manufacturer of the analyzer, as the manufacturer of the analyzer does not give the variational coefficient of repeatability. To estimate the validity, basic parametres of blood counts were measured to control materials from the company SEKK, Ltd.These materials are used to measure performance parametres. Validity measurements were used to calculate basic statistical parameters of which bias was calculated. It served to calculate the total analytical error of a laboratory and also it served to be compared to the total maximum error recommended by the company SEKK Ltd. in 2012. Passing-Bablock regression analysis was used to compare hematology analyzer Sysmex XT-2000i and hematology analyzer Sysmex XT-4000i, namely to compare the existing and the introducing analyzer and to compare open and closed mode of the introducing analyzer Sysmex XT-4000i. To compare analyzer Sysmex XT-4000i and Sysmex XT-2000i, which was regarded as referential, 40 patient samples were measured in a closed mode. To compare open and closed modes of analyzer Sysmex XT-4000i, 168 patient samples were measured. The measured values of all basic parameters were evaluated using MedCalc programme. The study showed that the device Sysmex XT-4000i meets the criteria required by CSN EN ISO 15189 Medical laboratories - Particular requirements for quality and competence and SOPO-C-06 Method validation/verification procedure for introducing laboratory hematology analyzer in Central laboratories Strakonice Hospital, Inc. section of hematology and blood storage. Comparison of the new hematology analyzer Sysmex XT-4000i to the current Sysmex XT-2000i showed that both analyzers are comparable.
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The Machines and Tools for the Fineblanking Technology
Šindelka, Marek ; Císařová, Michaela (referee) ; Peterková, Eva (advisor)
This work provides a brief overview of the used machines and tools designed for fineblanking. Fineblanking is a technology from the field of the surface forming, suitable especially for mass production, which can be used to make a functional component in a single operation. This work also lists the various methods of precision cutting, and describes the tools, that are the main reason for the quality of the product. Furthermore, in this work are listed some examples from today in practice used machines and their planting into the entire complex of production lines.
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The use of nanofibres strain gauges for construction of linear sensors
Kirchner, Jan ; Kůr, Jan (referee) ; Pernikář, Jiří (advisor)
The aim of this thesis was to determine the basic characteristics of behavior of nanofiber strain gauges and on the basis of experimental measurements to confirm the suitability of the design of the length sensors. There was a product designed with a swivel arm whose rotation burdens the nanofiber strain gauge affixed to the flat side of the cut. Some measurements were carried out to find out a suitable direction of the loading pressure and to reveal the area showing the linear behavior. This linear area is approximately between 44 ÷ 92 % of the range of the nanostrain gauge (0% maximum load tensile, 100% maximum load pressure). Other measurements dealt with temporal stability of the output value at each point. The outcome of these experiments was to determine the methodology and to propose the design of sensors for further tests, the aim of which was to develop a sensor for measuring small diameters (from 1 to 5 mm). K
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TRECVid Search Information Retrieval
Čeloud, David ; Mlích, Jozef (referee) ; Chmelař, Petr (advisor)
The master's thesis deals with Information Retrieval. It summarizes the knowledge in the field of Information Retrieval theory. Furthermore, the work gives an overview of models used in Information Retrieval, the data and the actual issues and their possible solutions. The practical part of the master's thesis is focused on the implementation of methods of information retrieval in textual data. The last part is dedicated to experiments validating the implementation and its possible improvements.
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Control of linear drives HIWIN
Roman, Jan ; Kaván, Martin (referee) ; Houška, Pavel (advisor)
The diploma thesis deals with three phase linear synchronous electric motors mounted on linear drive, its system of sensors and control. The analysis of working principle and classification of linear motor was done in the beginning part; analysis of the drives sensors system was made in the following chapter. The thesis also deals with the driver from the automation point of view, its tuning and behavior according to high dynamics and precise positioning. The last chapter discusses the issue of controlling two linear drives. Whole thesis was realized on a borrowed linear motor with driver from HIWIN corp.
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Combined Global Navigation Satellite System Module
Jurajda, David ; Jílek, Tomáš (referee) ; Žalud, Luděk (advisor)
The thesis objective is design of methodology focused on accuracy measurement in field of GPS/GLONASS receivers. Text is devided into five main parts. The first one is focused on GNSS technology. Second one deals with used coordinate systems and map projections (ETRS89, WGS84, UTM, Gauss-Krüger). Next part discusses statistical methods. Part four is focused on hardware. Then the final part describes experiment realization and obtained data analysis.
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Determination of chlorides in pharmaceutical substances
Čutová, Michaela ; Pharm.Dr.Tomáš Schenk (referee) ; Omelková, Jiřina (advisor)
The topic of this bachelor work is a validation of the method for „Determination of chlorides in pharmaceutical substance“ is made in a form of validation of an analythical method. This titration method with potentiometric indication was developed in a company Sicor and it is used for determination of the residual chlorides volume in the substance called Pemetrexed. Validation is a process which assess suitability of a given analythic system for gaining relevant data (results). Validation constists of four tests: precision, reproducibility, lineraity and test of solution stability, although the test of reproducibility was realized in other laboratory (QC). For determnination of the chlorides was applyed titrator 716 DMS Titrino with argent combined electrode. For a data evaluation were used software tiamo 1.1 and MS Excel.
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Accuracy of the facade of the historic building - methods, possibilities, conditions
DVOŘÁKOVÁ, Jitka
This thesis deals with methods of surveying the facade of the historic building. The introductory section is a brief history of measurement and guidelines, as well as various methods are described from oldest to youngest, including their accuracy in targeting the facade. In more detail, a method for scanning and photogrammetry, which is currently the youngest methods used in surveying facades. In conclusion, the evaluation methods in terms of accuracy and usability. The aim is to describe and evaluace different methods of surveying from history to the present, including the necessary instruments and their accuracy.
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