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Left-right asymmetry specification in vertebrates
Vrúbel, Matěj ; Soukup, Vladimír (advisor) ; Fabian, Peter (referee)
The left-right body axis, along with the dorso-ventral and antero-posterior axis, is certainly very important, but at the same time the most neglected body axis of bilaterally symmetrical animals. The asymmetrical distribution of visceral organs along this body axis is vital for many animals. In vertebrates, this asymmetry becomes established at early embryonic stages. An essential role in this process is played by the organizer, which is responsible for the correct establishment of the left-right axis. Among vertebrates, organizers of left-right asymmetry are found in different parts of the embryonic body, and with few exceptions, they are composed of cells with motile cilia, which create an unidirectional leftward flow of extracellular fluids in the organizer. The flow is probably sensed by the cells that surround the left side of the organizer. These cells respond to the aforementioned mechanical stimulus by triggering the Nodal signaling pathway. This signaling cascade results in the left-sided expression of the Pitx2 gene, which specifies the left side of the embryonic body. It appears, that the role of Nodal signaling pathway in determining left-right asymmetry is not only present in all vertebrates, but also is probably ancestral to bilaterally symmetrical animals. Another mechanism ensuring...
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Left-right organizer of body asymmetries in ray-finned fishes
Kupková, Anežka ; Soukup, Vladimír (advisor) ; Krylov, Vladimír (referee)
Left-right asymmetry of the body occurs across a number of organisms from invertebrates to vertebrates, and is mostly exhibited by the asymmetry of internal organs. These asymmetries are established at early stages of embryonic development due to the action of temporary structures called organizers of left-right asymmetry. In ray-finned fishes, the most-studied organizer is the so-called Kupffer's vesicle present in the teleosts. It is a hollow structure composed of monociliary cells. The cilia of these cells rotate and generate a leftward flow of extracellular fluid. The flow subsequently triggers the induction of the Nodal signalling cascade, which is responsible for left-right organ orientation and is considered evolutionarily conserved in vertebrates. The main participants in this pathway are the Nodal, Pitx2 and Lefty factors. In contrast to teleosts, the left-right organiser of non-teleost ray-finned fishes resembles the gastrocoel roof plate present in amphibians, which is apparently ancestral for ray-finned fishes. This bachelor thesis evaluates the origin and function of Kupffer's vesicle, describes the Nodal signalling cascade triggered by this organizer, and compares Kupffer's vesicle with the organizer of non-teleost ray-finned fishes.
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The Role of the Curator in Conditions of Contemporary Czech Art
Pechová, Gabriela ; Půtová, Barbora (advisor) ; Hoftichová, Petra (referee)
The bachelor thesis seeks to clarify the role of a curator of contemporary art in the context czech art scene. To achieve this objective the person of curator is set into the wide framework. Thesis starts with description of historical events which led to formation of this profession and influenced its evolution into the current form. The vital moment is division of a curator into two types in the second half of 20th century; a curator as employee of exhibitionary or collecting institution and an independent curator. This fact is crucial for the specification of exact responsibilities of a curator. It is this issue and also description of environment, where a curator currently operates, to which one of the chapters is dedicated. A place in the thesis is also given to the analysis of some factors, human and technical, which have a direct and also indirect influence on the work of a curator. The text is ended by a chapter about possibilities of education in the field of curating not only in the Czech Republic, but also abroad. Keywords: curator, contemporary czech art, mediator, organizer, manager
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Totality of LARP
Kloudová, Erika ; Vaněk, Vojtěch (referee) ; Klodová, Lenka (advisor)
In this work I focused on the possibility to develop LARP in the means of participation and performance. Furthermore, I focus on the continuity of individual games (segments) and the possibility of connecting various, already existing, LARP genres. In this series of games, the most striking of the genres is the political LARP, whose political charge has been intermingled by other LARP genres in my work.
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The Criminal Liability of the Organizer of a Criminal Offence
Brandtner, Anna ; Pelc, Vladimír (referee)
01 The Criminal Liability of the Organizer of a Criminal Offence Abstract This thesis focuses on one of the modalities of participation - on organizing. The provisions of Section 24 (1) a) of Act No. 40/2009 Coll. of the Criminal Code mentions organizing in the first place, indicating that it is the most serious form of participation. Organizing is also a form of participation which is quite specific to the Czech legal order. Foreign legal regulations often consider the Czech organizer to be the offender. The aim of this thesis was to thoroughly discuss the organizer of a criminal offence, to evaluate the reason for the frequent criticism of his inclusion among the participants of the crime and to suggest how should this legal institute be adapted. The thesis is divided into seven chapters, the first of which is the introduction and the final is the conclusion. The first part of this thesis deals with the theoretical foundations of participation. It briefly describes the possible approaches to the offender and the fundamentals of the unitary and the differentiated system, including their advantages and disadvantages. The meaningfulness of a differentiated system depends on the successful separation of the key persons involved in the criminal act from the less important ones. The following chapter focuses on...
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The Criminal Liability of the Organizer of a Criminal Offence
Brandtner, Anna ; Říha, Jiří (advisor) ; Tejnská, Katarína (referee)
01 The Criminal Liability of the Organizer of a Criminal Offence Abstract This thesis focuses on one of the modalities of participation - on organizing. The provisions of Section 24 (1) a) of Act No. 40/2009 Coll. of the Criminal Code mentions organizing in the first place, indicating that it is the most serious form of participation. Organizing is also a form of participation which is quite specific to the Czech legal order. Foreign legal regulations often consider the Czech organizer to be the offender. The aim of this thesis was to thoroughly discuss the organizer of a criminal offence, to evaluate the reason for the frequent criticism of his inclusion among the participants of the crime and to suggest how should this legal institute be adapted. The thesis is divided into seven chapters, the first of which is the introduction and the final is the conclusion. The first part of this thesis deals with the theoretical foundations of participation. It briefly describes the possible approaches to the offender and the fundamentals of the unitary and the differentiated system, including their advantages and disadvantages. The meaningfulness of a differentiated system depends on the successful separation of the key persons involved in the criminal act from the less important ones. The following chapter focuses on...
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The Role of the Curator in Conditions of Contemporary Czech Art
Pechová, Gabriela ; Půtová, Barbora (advisor) ; Hoftichová, Petra (referee)
The bachelor thesis seeks to clarify the role of a curator of contemporary art in the context czech art scene. To achieve this objective the person of curator is set into the wide framework. Thesis starts with description of historical events which led to formation of this profession and influenced its evolution into the current form. The vital moment is division of a curator into two types in the second half of 20th century; a curator as employee of exhibitionary or collecting institution and an independent curator. This fact is crucial for the specification of exact responsibilities of a curator. It is this issue and also description of environment, where a curator currently operates, to which one of the chapters is dedicated. A place in the thesis is also given to the analysis of some factors, human and technical, which have a direct and also indirect influence on the work of a curator. The text is ended by a chapter about possibilities of education in the field of curating not only in the Czech Republic, but also abroad. Keywords: curator, contemporary czech art, mediator, organizer, manager
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The Personality of Franciscan Jan Bárta in Totalitarian Régime in Bohemia
Drobková, Michaela ; Petráček, Tomáš (advisor) ; Ventura, Václav (referee)
The Personality of Franciscan Jan Barta in Totalitarian Régime in Bohemia Abstract This thesis describes briefly the life of Francis of Assisi. Further, it deals with history of male Fraciscan orders in Bohemia and Moravia. Also it concisely maps important events within several centuries. Above all it focuses on modern history in the period of the totalitarian regime in Bohemia. The dissertation pays attention to the personality of Jan Barta, the leading figure of Czech Franciscanism and to holy orders in our country, in the communist supremacy time. The thesis presents important moments in the life of this famous personality. It covers years in prison, writing theological works, organizing life and study of brethren and nuns, re-establishing communion of monastic orders in family - like houses. It mentions suffering before his death linked with his health problems that were caused by questioning from state security. Keywords Franciscan, friar, clergyman or priest, driver, holy order communion, prison, study, organizer, questioning, trial or case at court.
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