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The effect of menstrual cycle and cortisol and testosteron levels on strenght performance in female athletes
Novotná, Kateřina ; Heller, Jan (advisor) ; Pěkný, Martin (referee)
This study provides a comprehensive insight into the physiological and hormonal changes in female athletes during the menstrual cycle and their impact on performance training and recovery. It covers an overview of menstrual cycle physiology, the effects of steroid hormones on the female reproductive system, cortisol secretion examination, and the role of testosterone in female physiology. Furthermore, it analyzes the influence of individual menstrual cycle phases on the strength capabilities of female athletes and studies the relationship between cortisol and testosterone secretion and these abilities. It discusses the influence of the follicular phase on performance in the Wingate test, negative correlation between cortisol concentration and female athletes' strength performance, and differences in maximum performance between athletes with regular and irregular cycles. It highlights general limitations of research on women that need to be considered. Overall, this work contributes to the discussion on the relationship between hormonal changes and strength performance in female athletes, with potential future applications in training and sports performance. KEY WORDS menstrual cycle, hormones, strength capabilities, cortisol, testosterone, physical exertion
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Endocrine disruptors and their impact on mammalian oocyte developmental competence
Štenglová, Anna ; Němcová, Lucie (advisor) ; Ješeta, Michal (referee)
Endocrine disruptors (EDs) are defined as substances of exogenous origin that disrupt endocrine system. EDs are found in significant amounts in the natural environment, plastic products and flame retardants, leading to unavoidable exposure. Due to their broad effects, several organizations/ conventions aim to regulate their presence in the natural environment and limit, or even eliminate their production. By entering the body, they negatively affect development, reproductive, nervous or immune systems of various animal classes through hormones. Modified hormonal levels are associated not only with fertility issues, but also with physiological abnormalities, osteoporosis, depression or metabolic diseases. EDs affect the female reproductive system through hormonal modifications of the HHG axis, which can lead to an earlier pubertal onset in some cases. Under the influence of EDs, impairments can also be observed in the process of steroidogenesis, development of follicles and oocytes, particularly through meiotic defects, which can lead to premature ovarian failure or infertility. Multiple chemicals disrupt the females reproductive system across several generations through epigenetic effects. This work summarizes knowledge about these ubiquitous substances and their impact on female reproductive...
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Hormones and their presence in environmental
Sučková, Tereza ; Dvořáková, Petra (referee) ; Vávrová, Milada (advisor)
This thesis deals with the issue of hormones in the environment and analytical methods for the determination of hormonal substances in water and soil ecosystems. The thesis includes an overview of important hormone groups (divided into categories according to their chemical structure) and basic information about properties of chosen hormones, their sources and impacts on the environment. The next focuses upon methods of determination of hormones in soil and water ecosystems. Finally, a standard operational manual for analysis of estrogens in surface water has been created and is provided herein.
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Ecotoxicity of substances with hormonal effect
Cvikýřová, Zuzana ; Vávrová, Milada (referee) ; Zlámalová Gargošová, Helena (advisor)
This bachelor thesis deals with the fate and ecotoxicity of chosen substances with hormonal effect in the environment. This group of compounds covers steroid hormones, which are produced for these effects, but also a lot of xenobiotics, showing similar activity. The substances disrupt the endocrine system by various mechanisms. They can cause feminization, masculinization, disruption of reproduction, etc. In terms of chemical structure they belong to the group of phthalates, polychlorinated biphenyls, pesticides, heavy metals and others. The impact of these substances, especially on the aquatic ecosystem, which becomes their reservoir in most cases, was assessed.
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Determination of hormones in wastewater
Zouharová, Kamila ; Tulková, Tereza (referee) ; Vávrová, Milada (advisor)
The presented theoretical and practical study was focused on a single unit of drugs – hormones. In the present study were characterized in detail hormones as drugs or medical ressource and their mode of effect on the human body. Another important part of this study was focused on the evaluate of the incidence of estrogens in the environment and their possible impact on the aquatic ecosystem, mainly for waste water. The last part of study was processed analytical problems of determination of hormones. There were introduced pre-analytical and analytical methods – methods of isolation of hormones from the waste water and methods of thein final determination, which were based mainly on the separation processes.
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Assessment of the drinking water treatment plant effectiveness via ecotoxicological tests and screening analyses
Nývltová, Barbora ; Mravcová, Ludmila (referee) ; Zlámalová Gargošová, Helena (advisor)
The quality of raw water is deteriorating with the continuous increase in environmental pollution. Raw water is being modified to drinking water by technological processes, and it is therefore necessary to put increased demands on the efficiency of these technological processes and their possible innovation. Due to the fact that raw water is contaminated with different types of pollutants, it is necessary to continuously control the drinking water supplied to the public distribution network in order to ensure its quality. Drinking water treatment is still unable to treat the raw water perfectly, its pollution is only reduced to acceptable standards. For this reason, it is indispensable that the quality of drinking water is being checked regularly and at the same time the efficiency of individual technological processes of drinking water treatment is assessed. This includes screening analysis or eventually ecotoxicological tests. The thesis focuses on the efficiency of technological processes of drinking water treatment. Within the experimental part, samples of raw water and samples of water after each separation stage have been collected at the drinking water treatment plant in the Czech Republic. These samples have been subjected to ecotoxicological tests and screening analysis. Based on the ecotoxicological tests carried out on Thamnocephalus platyurus, Lemna minor and Vibrio fischeri, we can assume the emergence of harmful chlorinated by-products, resulting to nearly 100% mortality in T. platyurus. The results of the screening analysis carried out indicate, after the extraction of specimens by the SPE method using HPLC/MS, that the most effective method for the removal of hormonal substances is ozonization.
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Interactions of hormones and drugs with soil organic matter
Krajňáková, Soňa ; Enev, Vojtěch (referee) ; Klučáková, Martina (advisor)
This thesis is focused on the problem of interaction of hormones and drugs with a soil organic matter. The most commonly occurring drugs are described, as well as their features, behaviour and possible factors influencing this behaviour. These substances are frequently transported to the soil through a sewage treatment plant, as the cleaning process of wastewater is not effective enough to ensure complete removal of these substances. Once in the soil, the life of organisms in this environment can be negatively influenced. The soil used in experiments was not contaminated with any of these substances as it was used as a matrix for sorption and desorption. Two experiments were conducted using Ibuprofen, where its sorption and desorption on the soil was observed. The intention was to ensure detection of changes which occurred in the concentration of Ibuprofen after concluding these processes. Liquid chromatography method with mass spectrometric detection was used for a final analysis.
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The influence of thyroid hormones and adrenal glands on mental function
Augustinová, Jana ; Šivicová, Gabriela (advisor) ; Špinka, Marek (referee)
This thesis focuses on effects of thyroid and adrenal hormones on mental functions, especially on cognitive functions and emotions. In the case of adrenal hormones it will also focus on stress and burnout syndrome, which are not considered as mental functions, but are connected to both psyche and the above mentioned hormones. The text is divided into two parts. The first, theoretical part deals with the anatomy and histology of these two organs, hormones that they produce and their influence on overall physical condition and pathology. The main section of this theoretical part deals with the description of influence of thyroid hormones and adrenal glands on the above mentioned mental functions. This work is based on both earlier and contemporary research, but predominantly on foreign research. In the second, empirical part, a proposal for longitudinal study of cortisol and thyroxine levels during depression treatment is presented. Klíčová slova: Hormones, thyroid glang, adrenal gland, mental functions, cognitive functions, emotions, stress, cortisol, thyroxine
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Anxiety disorders from a biological and psychological perspective
Záplatová, Klára ; Šivicová, Gabriela (advisor) ; Hrachovinová, Tamara (referee)
Barchelor thesis focuses on anxiety disorders from a biological and psychological perspective. This thesis aims to provide anxiety disorders in their entireness. For this reason, thesis focuses on psychological and physical symptoms of anxiety. Topic contains unconscious symptoms manifesting inside of a man. Thesis is divided into two main parts. First one consists of literature review, the second one consists of experiment design. Experiment design deals with physiological symptoms of social phobia. It is focused on specific brain areas and cortisol level in anxiety feeling as well as to feeling of a man during the experiment. Powered by TCPDF (www.tcpdf.org)
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