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Application limits of sublingual drug administration. 1
Turnerová, Lenka ; Doležal, Pavel (advisor) ; Vachek, Josef (referee)
The theoretical part of thesis provides basic information about the sublingually administered drugs, describes the primary facts of the medicated membranes for oral systemic administration and about dextrans as the pharmaceutical substances. The experiment focuses on transmucosal in vitro evaluation of permeation of the dextrans of three different molecular weights from aqueous environment throughout sublingual membrane. The measurements of fluxes of caffeine as a marker at the opening period of permeation experiments were performed. An acceptor phase was always the phosphate buffer, pH 7.4. Determination of caffeine was performed by HPLC, the dextrans were determined spectrofluorimetrically. The average flux of caffeine is J = 1370 µg/cm2 .h-1 , SEM = 100,8 (n = 17). The proof of the transmembrane passage of all the mentioned fluorescent-labelled dextrans was given. Surprisingly, the lower permeation rates of dextran 4000 (J = 28,1 µg/cm2 .h-1 ; SEM = 21,4) comparing with dextran 20 000 (J = 42,0 µg/cm2 .h-1 ; SEM = 11,8) were found.
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Application limits of sublingual drug administration. 1
Turnerová, Lenka ; Doležal, Pavel (advisor) ; Vachek, Josef (referee)
The theoretical part of thesis provides basic information about the sublingually administered drugs, describes the primary facts of the medicated membranes for oral systemic administration and about dextrans as the pharmaceutical substances. The experiment focuses on transmucosal in vitro evaluation of permeation of the dextrans of three different molecular weights from aqueous environment throughout sublingual membrane. The measurements of fluxes of caffeine as a marker at the opening period of permeation experiments were performed. An acceptor phase was always the phosphate buffer, pH 7.4. Determination of caffeine was performed by HPLC, the dextrans were determined spectrofluorimetrically. The average flux of caffeine is J = 1370 µg/cm2 .h-1 , SEM = 100,8 (n = 17). The proof of the transmembrane passage of all the mentioned fluorescent-labelled dextrans was given. Surprisingly, the lower permeation rates of dextran 4000 (J = 28,1 µg/cm2 .h-1 ; SEM = 21,4) comparing with dextran 20 000 (J = 42,0 µg/cm2 .h-1 ; SEM = 11,8) were found.
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Vegetarianism as a Consumer Trend
Dvořáková, Anna ; Chylíková, Hana (advisor) ; Turnerová, Lenka (referee)
The aim of this diploma thesis is a complete analysis of vegetarianism, as a consumer trend, including forecasts of future potential of this trend for the field of retailing in the Czech Republic. The thesis deals with the influence of various aspects of vegetarianism on the market in the Czech Republic. First, vegetarianism as such is characterized. The next chapter describes the supply side of vegetarian products on the Czech market, labeling of vegetarian food and its availability. Then, the thesis deals with with the consumer's purchasing decision-making process in relation to vegetarian products and marketing strategies that are used in relation to vegetarian products. The work is complemented by a questionnaire and a final SWOT analysis. In the thesis, a market potential of vegetarian products with one particular type of positioning was identified.
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Business on the Czech market in the form of franchising
Hrubcová, Veronika ; Chylíková, Hana (advisor) ; Turnerová, Lenka (referee)
This bachelor thesis deals with "Business on the Czech market in the form of franchising ". It is divided into three main chapters. The first chapter deals with the theoretical side of things, the advantages and disadvantages of franchising, defines the main concepts and types of franchising, franchising definitions used, and also describes a brief history of the franchise. The second chapter describes the development of franchising in the Czech Republic organizations for franchising operating in the Czech republic and provides the largest franchise systems operating in our territory. The third and last section contains a description of the functioning of franchise concept in the company and using SWOT analysis compares the strengths, weaknesses, opportunities and threats of a concept, in this case the company CrossCafe Original Ltd.
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Analysis of Franchising on the Example of Benzina Ltd.
Tajzlerová, Nikola ; Chylíková, Hana (advisor) ; Turnerová, Lenka (referee)
This Bachelor thesis deals with business through franchising. The first part defines franchising from the theoretical point of view, mentioning basic pillars of the franchise agreement and the advantages and disadvantages for the franchisor/franchisee. The second part, divided into two chapters, illustrates franchising by using the example of company Benzina and the specific petrol station Benzina-Přelouč. The aim of the thesis is to create a comprehensive view of the concept of this company and to assess whether it is sufficiently advantageous for the franchisee. For proper assessment, the competition analysis, the SWOT analysis and the analysis of revenues and expenses are carried out.
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Organic food in current retailing
Horká, Jana ; Chylíková, Hana (advisor) ; Turnerová, Lenka (referee)
The main goal of my diploma thesis is to analyze the offers of organic food in chosen retail chains operating in the Czech market. At the beginning there are defined retail and retailing and there is briefly outlined the development of retail in the Czech Republic. In the second chapter there is introduced organic farming, its definition, goals and its current position in the world and in the Czech Republic. In this chapter is defined what is organic food, how is organic food labeled and which organizations do this business in the Czech Republic. The third chapter analyses the situation in the organic food market in the Czech Republic and there are introduced certain marketing activities and projects to promote organic food. The next chapter analyses the current retail net in the Czech Republic and in the following chapter there are introduced the retail chains chosen for the analysis of their assortment of organic food. The last chapter deals with analysis of assortment of organic food in chosen retail chains.
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Franchising as a Form of Market Entry
El Gindy, Rasia ; Chylíková, Hana (advisor) ; Turnerová, Lenka (referee)
My bachelor thesis deals with franchising as a form of market entry. It is divided into four main chapters. The fisrt chapter focuses on the theoretical definition of franchising, its characteristic features, its advantages and disadvantages. The second chapter is related to the process leading to the application of franchising in practice. The third chapter monitors the situation of franchising in the Czech Republic from the past to the present day. The last chapter applies to the franchising concept of SUBWAY.
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The market of food supplements and their trustworthiness
Hroudová, Martina ; Chylíková, Hana (advisor) ; Turnerová, Lenka (referee)
The bachelor thesis deals with the market of food supplements and their trustworthiness. The aim of this thesis is to inform about the current situation on the market of food supplements in the Czech Republic and abroad, to highlight the importance of consumption of food supplements and to present conclusions obtained during a personal survey. The work could be divided into two parts, the first part is theoretical and the second one practical. The purpose of the first part is primarily to introduce the topic of food supplements and to provide information about the market of the food supplements as well as about the food supplements themselves. The practical part provides information about shopping behavior of customer and about his general knowledge in this area.
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Marketing of franchising concept Švejk restaurant
Sochor, Radovan ; Filipová, Vladimíra (advisor) ; Turnerová, Lenka (referee)
This bachelor thesis deals with marketing franchising chain Švejk restaurant. The aim of this work is to analyze the concept of Švejk restaurant from a theoretical and practical perspective. The first chapter covers the general knowledge about franchising. The second chapter focuses on the basic theoretical knowledge of marketing. The third chapter describes the basic characteristics of the concept Švejk restaurant. The fourth chapter deals with the concept of marketing activities. The fifth chapter is focused on the research. The last chapter is the final part of the work where is designed marketing plan concept.
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Spotřebitelský úvěr jako nástroj získávání nových zákaznických segmentů
Holubinková, Hana ; Turnerová, Lenka (advisor)
Podle údajů České Národní banky má zadlužování českých domácností stoupající trend. V květnu jejich dluhy u bank a finančních institucí vzrostly o 11,16 miliardy korun na 456,5 miliardy. Za minulý rok 2005 vzrostly dluhy domácností o více než 100 miliard korun. ČNB poskytuje tuto statistiku každý měsíc v národním měnovém přehledu, který je odvozen z bilancí měnových finančních institucí. Za posledních 12 měsíců už dluhy domácností vzrostly o necelých 112 miliard korun, to je nárůst o 32.5%. Česká republika přebírá model západoevropských domácností, které využívají úvěrů k financování svých potřeb. Část těchto úvěrů jsou hypotéky, které nepatří mezi rizikové, protože jsou kryty nemovitostmi, ale tempo růstu zadlužení domácností spotřebitelskými úvěry se při stávajícím dynamice může stát rizikové. Podle pana Racocha z České národní banky jsou problémem převážně některé spotřebitelské půjčky pocházející zejména z nebankovního sektoru. Jedná se o to, že úvěry jsou teď dostupné pro každého, kdo má stálý příjem. Ne každý si je schopen propočítat, zda si úvěr může dovolit, zda břemeno splácení unese a zda se nedostane do spirály zadlužování. Reklama lákající spotřebitele je velmi sugestivní. Jaké vlivy působí na zákazníka během nákupu, jaký rozhodovací proces se v něm odehrává bych ráda rozebrala v mé práci. Chci také zjistit, proč je nyní jednoduché získat úvěr a proč se finanční instituce rozhodly, že nalákají nové zákazníky právě na spotřebitelské úvěry? Jaké segmenty zákazníku jsou majoritní a jak je tyto instituce přesvědčily k větší spotřebě a následnému zadlužení? Jedním z dalších podstatných problémů je to, že některé nebankovní subjekty nabízejí u spotřebitelských úvěrů nepřiměřeně vysoké úroky. To se zdá býti na první pohled nezákonné, ale jelikož tyto subjekty na trhu stále působí, asi tak jednoduché to nebude říci, že jednají proti zákonu. Dívám se proto na spotřebitelské úvěry i z legislativního hlediska, na to, jak je o nich pojednáno v zákoně a kdo je reguluje. Slovo lichva již znali i staří Římané, zná ji tedy i český?
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