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The collective memory of the forcibly ejected inhabitants: The oral history about the 2nd World War from Neveklov and its neighbourhoods
Štěpánková, Jana ; Šalanda, Bohuslav (advisor) ; Otčenášek, Jaroslav (referee) ; Janeček, Petr (referee)
This Dissertation is the benefit to studying of the questions of the oral history of forcibly ejected inhabitants of Neveklov and its neighbourhoods during the 2nd World War. About this region, there exists authentic testimony and this territory is fixed in the collective memory. The oral history is a highly valued literary source. Its value is in the authenticity, which is characterized by selectivity and represents another point of view. The essay brings the unique opportunity to get acquainted with witnesses of the wartime. At present this testimony is unknown or is being forgotten in the offical documents. The essay follows the researches of Jaromír Jech from the middle of the last century. If we compare the results of both researches, we get the view of the importance of forcible displacement of Czech inhabitants in a demarcated region. Result of this work is the analysis of the results obtained with the help of the modern approaches that are based on the method of the oral history, which is a part of the qualitative research, with an emphasis on general objectives and context. The essay brings new testimonies of events that have not been presented and published yet. It also simultaneously maps over the current state, i.e. the reflection of the forcible war persecution on the present times and...
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Display of indiscipline from elementary teachers perspective
ŠTĚPÁNKOVÁ, Jana
The aim of this bachelor thesis is to map expression of indiscipline at elementary schools and is describing teacher's perspective to their competencies in solving indiscipline problems. This thesis is divided in theoretical and practical part. In theoretical part is described basic theoretical knowledges related to indiscipline at schools and approach to discipline at schools. Practical part elaborates on show of indiscipline from teacher's perspective, which they face at elementary schools. In next part author of this thesis elaborates more on teachers feeling about facing situation, which they face at schools. In accordance with aim of this thesis are used quantitative research and questionnaire survey to collect data. As sample for surveys are used elementary schools' teachers.
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Characterization of flubendazol reduction in human in vitro
Štěpánková, Jana ; Szotáková, Barbora (advisor) ; Novotná, Eva (referee)
ASBSTRACT Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Mgr. Jana Štěpánková Supervisor: Prof. Ing. Barbora Szotáková, Ph.D. Title of Thesis: Characterization of flubendazol reduction in human in vitro Flubendazole (FLU) is an anthelmintic of the benzimidazole type used as a treatment or prophylaxis of helminthoses in livestock and wild animals. FLU is also registered for the treatment of parasitic diseases caused by intestinal nematodes in humans. Its mechanism of action lies in its specific binding to tubulin, which disrupts the structure and function of microtubules for the therapy of parasitosis in humans. The advantage of this drug is also the low systemic toxicity. That is why the anticancer activity of FLU is now under study. The aim of this rigorous work was to characterize the reduction of FLU in human liver subcellular fractions as this information is still lacking in available literature. Stereospecificity, subcellular localization, preference of coenzymes, enzyme kinetics of FLU reduction, and activity of enzymes involved in FLU reduction were studied in this project. Measurement results have shown that FLU is predominantly reduced in cytosol and nicotinamide adenine dinucleotide phosphate reduced (NADPH) coenzyme is preferred. FLU...
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Estimation of the Company Market Value for Strategic Concept
Štěpánková, Jana ; Faltýnek, Jiří (referee) ; Režňáková, Mária (advisor)
The master s thesis is focused on estimation of the company value for the purpose of legal form transformation. The analysis of the company and corporate environment and valuation of risks and contribution of the change of legal form are included. In the practical part the income method approach and asset based approach are applied. The company value is estimated by the capitalization of earnings method and method of valuation based on historic costs.
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Principle of superficies solo cedit and its importance in land law
Štěpánková, Jana ; Franková, Martina (advisor) ; Žákovská, Karolina (referee)
The aim of the thesis is to describe the concept of the superficial principle in the valid legal regulation and its influence on land law relations. As a result of the reintroduction of the superficial principle into the legal order of the Czech Republic by Act No. 89/2012 Coll., The Civil Code, all that is associated with the earth's surface becomes part of the given land. The thesis is divided into five structured chapters. The first chapter is devoted to land law as an interdisciplinary law system. The aim of second chapter is to explain the key importance of the superficial principle within the context of land law. The third chapter deals with the historical background of the development of legal relations to immovables in the territory of the Czech lands, also including the introduction of the Roman settlement as the basis of the superficial principle. The next part of the thesis contains the interpretation of the most important legal institutes related to the superficial principle in the context of the valid law. The chapter further describes exceptions to the principle. The fifth part of the thesis is focused on the analysis of selected land law relations influenced by the superficial principle.
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Effect of prenylflavonoids on detoxification enzymes in hepatocytes
Štěpánková, Jana ; Szotáková, Barbora (advisor) ; Skálová, Lenka (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Jana Štěpánková Supervisor: Prof. Ing. Barbora Szotáková, Ph.D. Title of Diploma Thesis: The effect of prenylflavonoids on detoxifying enzymes in hepatocytes Prenylated flavonoids are secondary metabolites of many plants, for example hops and fig. They affect the human organism in many positive ways, for example they have antioxidazing, anticancer, anti-inflammatory, estrogenic and antibacterial effects. These effects are even more emphasized due to their prenylated group. Only dietary supplements have sufficient amount of these substances and that is the main reason of patients' purchase. Cytotoxicity of prenylated flavonoids xanthohumol (XH), isoxanthohumol (IXH), 6- prenylnaringenin (6PN) and 8-prenylnaringenin (8PN) towards isolated rat hepatocytes by using the MTT test was studied in this diploma thesis. Furthermore the influence of these prenylflavonoids on the activity and expression of phase I. biotransformation enzymes NAD(P)H:chinonoxidoreductase (NQO1) and aldehydreductase (AKR1A1) was examined. The results of the MTT viability test showed that 6PN and 8PN raise the viability of rat hepatocytes. The viability of hepatocytes was increased by 25 μM XH, however higher...
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Figure of the Teacher in Russian Classical Literature
Štěpánková, Jana ; Hříbková, Radka (advisor) ; Hlaváček, Antonín (referee)
My bachelor's dissertation is aimed at evaluating the social status of a teacher's profession referring to Russian classical literature. The introductory part deals with cultural- historical contexts of functioning of Russian education in 19th century. The main content of my work is to introduce and analyse the issue of social status of a teacher as an important creator of children's personality mainly according to the book The little demon by F. Sologub and short stories by A. P. Čechov. Comparing the two mentionened works and other literary references the dissertation is trying to confirm or disprove the hypothesis that the profession of a teacher in Russian literature is seen as one of the most important jobs whose aim is to educate the future generation so that it is profitable for itself and for the society. The thesis concludes that teacher figures were portrayed predominantly in a negative manner. Authoritative attitude towards the children was often intensified by the teacher's alcoholism and resulted in the pupils being physically punished on a daily basis.
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The collective memory of the forcibly ejected inhabitants: the oral history of Neveklov ant its neighbourhood during the 2nd World War
Štěpánková, Jana ; Šalanda, Bohuslav (advisor) ; Janeček, Petr (referee)
This Rigorous Thesis is the benefit to studying of the questions of the oral history of forcibly ejected inhabitants of Neveklov and its neighbourhoods during the 2nd World War. About this region, there exists authentic testimony and this territory is fixed in the collective memory. The oral history is a highly valued literary source. Its value is in the authenticity, which is characterized by selectivity and represents another point of view. The essay brings the unique opportunity to get acquainted with witnesses of the wartime. At present this testimony is unknown or is being forgotten in the offical documents. The essay follows the researches of Jaromír Jech from the middle of the last century. If we compare the results of both researches, we get the view of the importance of forcible displacement of Czech inhabitants in a demarcated region. Result of this work is the analysis of the results obtained with the help of the modern approaches that are based on the method of the oral history, which is a part of the qualitative research, with an emphasis on general objectives and context. It also simultaneously maps over the current state, i.e. the reflection of the forcible war persecution on the present times and its viability in the future, functionality of the generation transfers and the ways of...
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Intertextuality in academic writing: citation in soft and hard sciences
Štěpánková, Jana ; Malá, Markéta (advisor) ; Šaldová, Pavlína (referee)
Based on a corpus analysis of 72 research articles, this thesis examines citation practices in four academic disciplines, two soft (linguistics and art history) and two hard (biology and astronomy). The first part provides quantitative results for the usage of two basic types, integral and non-integral citation. The non-integral type is preferred mainly in biology (91%), whereas astronomy and linguistics do not show such strong preference. In art history, both types are used with similar frequencies. The second part is focused on integral citation and examines instances of its sub-types (verb-controlling, naming and non-citation). The third part analyses the distribution of citations in the individual sections of research articles which shows to be dependent on the structural organization of the article. In general, two tendencies have been found: in articles with IMRD structure (biology and linguistics), citations occur mainly in the introduction and discussion. In astronomy and art history, citations are almost evenly distributed across the text. The last part of this thesis is focused on reporting verbs and their semantic classification (research, cognitive and discourse acts). Astronomy shows strong preference for research acts verbs, whilst biology employs this type only slightly more often...
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