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Working Time and Rest Periods Guidelines
Štefko, Martin ; Matejka, Ján ; Feigerlová, Monika ; Pichrt, J.
The Guidelines deal with issues pertaining to the working hours and rest periods, summing up all relevant data and applying them to the topic at hand. The guidelines are aimed at increasing the efficiency of education and training of Labour Inspection State Office (SUIP) inspectors and regional inspection offices (OIP), and at providing assistance in the execution of their control-related activities.
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Fundamental Principles of Labour Law
Štefko, Martin
We may document cases from both the past and the present when despite of subsidiary applicability of the Civil Code (Civil Law) it was not possible to address the needs of economic life satisfactorily. In this case, the fundamental principles of Labour Law may play the key role. Their task is to form a bridge between the general (civil) and special part of Labour Law.
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Development of a general and modular approach to C-nucleosides
Kubelka, Tomáš ; Štefko, Martin ; Bárta, Jan ; Joubert, Nicolas ; Urban, Milan ; Chapuis, Hubert Jean ; Hocek, Michal
Highly efficient and modular approach was developed for the synthesis of various types of new (het)aryl C-nucleosides. This protocol consists of the synthesis of haloaryl-C-nucleoside intermediates, followed by a functional group transformation to introduce various substituents. Using this approach protected 2′-deoxy-C-nucleosides bearing halogenated benzene, pyridine, thiophene, furane and pyrimidine were prepared. These intermediates were then submitted to a wide range of palladium-catalyzed reactions. The same approach was also used for preparation of C-nucleosides bearing ribofuranose moiety. Functional ribofuranosides bearing diverse substituted pyridine and benzene nucleobases were prepared in this way.
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Implementation of the Euro in the Czech Republic in comparison to implementation in Slovakia
ŠTEFKO, Martin
The diploma thesis deals with the topic of implementation of the euro in the Czech Republic in comparison to implementation in Slovakia. The aim of the thesis is the analysis of systems of the implementation in the Czech Republic and the Slovak Republic, the comparison of differences and description of reasons why the Slovak Republic implements the Euro earlier than the Czech Republic. The partial aim of the thesis is to discover the impact of the implementation in both countries {--} the real one in the Slovak Republic and the anticipated one in the case of the Czech Republic. The thesis is divided into two parts for fulfilling aims. The first half of the thesis gives a survey of history of the monetary policy in the European Union and in the Czech Republic. The second half of the thesis focuses on the comparison itself and analyzes the implementation of the Euro in both selected countries. Main criteria for analysis are the fulfilling of Maastricht criteria, adoption of reforms and the authorization of legal acts.
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Deposit operations
ŠTEFKO, Martin
This bachelor thesis deals with deposit operations of banks that are provided for clients. It is focusing principally on the bearing interest of this operations and their description as products of selected banks {--} Česká spořitelna, Československá obchodní banka and Komerční banka. The aim of this bachelor work is to show how particular types of selected operations are paid interest on, and at the same time to show the calculation of the interest in a clear and understandable way. The partial aim of work is comparison of products that are provided by selected banks. The comparison is based on advantages that are results of more profitable benefits and on a higher interest rate. Calculation of interest is applied on rates of three selected banks.
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Modulární metodika na přípravu 3- a 4- substituovaných benzenových a anilínových C-ribonukleosidů
Štefko, Martin ; Hocek, Michal
A novel modular, efficient and practical methodology for the preparation of 3- and 4-substituted phenyl and aniline C-ribonucleosides was developed. The key intermediates were synthesized in two steps from TBS-protected ribonolactone in 75% and 66% yields, respectively, as pure beta-anomers. The bromophenyl intermediates were subjected to a series of palladium catalyzed cross-coupling, aminations and alkoxylation reactions to give, after deprotection a series of free 1 beta-(3- and 4-alkyl, -aryl, -amino -alkoxyphenyl and -hetaryl substituted phenyl)-C-ribonucleosides (20 examples).
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