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Synthesis of Neurosteroids: Modulators of NMDA Receptor
Šťastná, Eva ; Chodounská, Hana (advisor) ; Klinotová, Eva (referee) ; Drašar, Pavel (referee) ; Hampl, Richard (referee)
Charles University in Prague Faculty of Science Department of Organic and Nuclear Chemistry Karlova Universita v Praze Přírodovědecká fakulta Katedra organické chemie a jaderné chemie Mgr. Eva Šťastná Synthesis of Neurosteroids: Modulators of NMDA receptor Syntéza neurosteroidů: modulátorů NMDA receptoru PhD. Thesis Abstract Autoreferát disetační práce Praha 2009 Prague, 2009 Scientific Presentations and Posters Papers Šťastná E.: Diazomethane (CH2N2). Synlett, 2007,15,2454. Stastna E., Chodounska H., Pouzar V., Kapras V., Borovska J, Cais O., L Vyklicky L.: Synthesis of C3, C5, and C7 pregnane derivatives and their effect on NMDA receptor responses in cultured rat hippocampal neurons. Steroids 2009, 74, 256-263. Kapras V., Šťastná E., Chodounská H., Pouzar V., Krištofíková Z.: Preparation of steroid sulfamates and their interaction with GABAA receptor. Coll. Czech. Chem. Comm., submitted, manuscript number CCCC/2008/000187. Eignerová B., Slavíková B., Buděšínský M., Stastna E., Kotora M.: Synthesis of Fluorinated Brassinosteroids Based on Alkane Cross-Metathesis and Preliminary Biological Assessment. J. Org. Chem., under revision, manuscript number jo-2009- 002079. Patents Stastna E., Chodounska H., Cais O., Vyklicky L., Kapras V., Pouzar V., Kohout L.: Steroidní anionické sloučeniny, způsob...
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Beijing 2008. The Corporate Project
Šťastná, Eva ; Čáslavová, Eva (advisor) ; Kindová, Alena (referee)
BIBLIOGRAFICKÁ IDENTIFIKACE Jméno a příjmení autora: Eva Št'astná Název diplomové práce: Korporační projekt Peking 2008 Název diplomové práce v angličtině: Beijing 2008 The Corporate Project Katedra: Kinantropologie Obor: Management tělesné výchovy a sportu Vedoucí diplomové práce: Doc. Ing. Eva Čáslavová, CSc. Rok obhajoby: 2006 Cílem mé diplomové práce bylo vytvoření celistvé koncepce projektu aplikovatelného v praxi. Hlavní podstatou celé práce jsou jednotlivé části kompozice, které se vzájemně prolínají a tvoří jednotný podklad pro realizaci akce podobného typu. Projekt jsem zaměřila na blížící se mezinárodní sportovní událost celosvětového významu. Jsem si plně vědoma toho, že mnohá fakta, z nichž jsem v době zpracování diplomové práce čerpala, projdou během doby příprav Olympijských a Paralympijských her v Pekingu řadou změn a výsledný koncept by se tak od zpracovaného teoretického podkladu významně lišil. Hlavním úkolem však nebylo zhotovení neměnného materiálu, svým čtenářům si takdovoluji předložit návrh, jak postupovat při postupné realizaci podobné aktivity. Klíčová slova: projekt, korporační, olympijský, paralympijský, Peking, partner Keywords: project, corporate, Olympic, Paralympic, Beijing, partner
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Oxidation barriers prepared by electrochemical procedures
Šťastná, Eva ; Pouchlý, Václav (referee) ; Jan, Vít (advisor)
A process with aim to prepare an oxidically and thermal resistant layer was performed on the samples from clear aluminium (99,99+ %, VÚK čisté kovy, s. r. o.) and on the samples from clear titanium (99,95 % Goodfellow) with a layer from sputtered aluminium (99,99 %, VÚK čisté kovy, s. r. o.), An oxidic layer was prepared on the samples by anodization in the oxalic acid. The layer had fine, hexagonally organized pores with the diameter of 30 nm. During the following processing was the structure prepared for the electrochemical deposition of copper to the pores. The aim of the electrodeposition was preparation of copper nanowires deposited into the pores of the oxidic layer. The process was performed in the solution of copper sulfate and sulfuric acid in water. The controlling parameter of the deposition was voltage which had a very asymmetric period. The period had to be optimized for a successful preparation of the wires. The result of the whole process was structure with oxidic matrix whose most of the pores were filled with copper.
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Self-organized nanostructured oxide layers
Šťastná, Eva ; Pouchlý, Václav (referee) ; Jan, Vít (advisor)
Series of anodization experiments was conducted on pure aluminium (99,95 Goodfellow) substrates with the aim to map the possibilities and evaluate available techniques. Oxalic acid electrolyte was used for anodization at different voltage levels ranging from 20 to 60V, while current was always measured continuously during the experiment. The influence of substrate surface treatment, time and grain size of the substrate was documented for as anodized oxide structures using FEG-SEM. Well aligned and evenly distributed pores of the diameters ranging 20- 35 nm were achieved. Extremely fine pores down to 10 nm were achieved using the step-down technique governed by current limitation. Further post-anodizing treatment was evaluated – pore widening by chemical and electrochemical etching, which resulted in pores 80nm wide. The feasibility of electrodeposition of metallic wires directly into the AAO structure without substrate removal was evaluated. DC, AC symmetric and non-symmetric voltage setups were used. The deposition experiments results varied strongly depending on the post anodization treatment. For combination of pore-widening after anodizing with step-down stage, the deposition of copper nanowires was achieved. For simple step-down procedure, creation of very fine copper particles was realized using non-symmetric AC deposition. Further experiments and feasibility of metals electrodeposition in the AAO pores without substrate removal is discussed.
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Liability for defects in sale contract
Šťastná, Eva ; Hásová, Jiřina (advisor) ; Švarc, Zbyněk (referee)
This thesis carried out an analysis of various aspects of liability for defects in the contract of sale under the New Civil Code. The text discusses general liability and displays special treatment contracts. The thesis includes a division of defects, deals with a liability for defects focused on the sale contract and a contract for work. Further specification party beneficiary rights of defective performance and other rights to the settlement of total loss. There are given rights principles and procedures of the defects of the complaint procedure. The text contains rules on liability for defects in international trade. The thesis is the comparison of new and old legislation, the most significant changes and an overview of the consequences of changes to the consumer.
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importance of coffee in international business
Šťastná, Eva ; Zamykalová, Miroslava (advisor) ; Veselá, Petra (referee)
The first part focuses on the characteristics of coffee, where it comes from and how we distinguish between different types of coffee. Chapter first describes the actual facts about coffee types, processing, marketing and subsequent developments and current trends. The second part is devoted to the concept of Fair Trade. Firstly I describe the terminology and then cafes. In the practical part I profile café Korunní and the results of questionnaires.
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Multiyear Unemployment Like a Social Problem
ŠŤASTNÁ, Eva
The study describes the women´s position in the labour market after their maternity leave. The first part is focused on the characteristics of the labour market and on the questions of gender role and the equal job opportunities. Further follows the employment rate of the women returning back of thein maternity leave. The practical part is focused on the empirical research which inquires into how the women experience their maternity leave and how this period is evaluated by their husbands. The goal is to find out if there is an equivalence of the husband´s images and how the women experience the maternity leave.
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Franchising as a method of entering the market
Šťastná, Eva ; Turnerová, Lenka (advisor) ; Krajča, Jiří (referee)
The aim of this bachelor thesis is to analyse options of financing franchising in the Czech Republic. The first part is focused on franchising in global perspective. Then the actual situation in the czech franchising market is evaluated. The main part is devoted to the particular ways of financing franchising and afterwards the methods are implemented to the czech franchise business Český grunt.
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