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Clinical and pathologic correlation of complications of intensively treated hemato-oncological patients with a targeted focus to the involvement of the oral cavity and rare case of secondary neoplasia.
Vokurka, Samuel ; Boudová, Ludmila (advisor) ; Chlumská, Alena (referee) ; Faber, Edgar (referee)
Summary: In this thesis section "Oral Mucositis (OM) and oral Graft versus Host Disease (GVHD) in patients after allogeneic stem cells transplantation and with focus to FLU/MEL conditioning regimen" the author deals with following issues: 1. Literature overview: The overall negative impact of OM is mentioned and the complex pathogenesis, clinical characteristics, incidence and factors influencing both OM and GVHD are described. The histological features of GVHD and classification of it are mentioned, too. Conventional and reducedintensity conditioning transplant regimens, including FLU/MEL are presented. 2. Methodological section: Prospective observational study of 117 patients after allogeneic stem cells transplantation with BU/CY2/±ATG (26%), FLU/MEL (60%), FLU/CY (9%), Bu/FLU/ATG (2%) and HD-CY/ATG (2%) conditioning regimens. OM assed according to WHO criteria, GVHD assessed according to NIH criteria accepted by the EBMT. The statistical univariate analysis performed by means of GraphPad In Stat - Statistica Software (Man- Whitney, Fisher, t-test), p<0,05 considered significant. Multivariate analysis used in OM risk factors assessment. 3. Results: The OM incidence was significantly dependent on pre-transplant conditioning regimen (Bu/CY2/±ATG: 100%, FLU/MEL: 78%, FLU/CY: 9%, p=0,0001) in multivariable...

Financial interest of retail store managers on store results - analysis of management accounting instruments
Benešová, Zuzana ; Stránský, Jakub (advisor) ; Kvasničková, Iveta (referee)
Author of the work: Zuzana Benešová Head of the work: Ing. Jakub Stránský, CEMS MIM Goals: Analysis of the system of compensations and benefits among the retail company Ahold Czech Republic, a.s. The connection between the bonuses and store's financial results. Financial interest in other criterias such as: fresh goods, short waitlines, clean store, helpful and friendly staff,... Literature: Cimer P. & Zadražilová D. a kol, Retail Management, Management Press, Praha 2007 Drury C., Management and cost accounting, 7th edition, 2008 Dvořáková Z. a kol, Management lidských zdrojů, C.H. Beck, Praha 2007 Fibírová J., Šoljaková L., Wagner J., Nákladové a manažerské účetnictví, Aspi, Praha 2007

Diagnostic morphological features of PDGFRA-mutated gastrointestinal
Daum, Ondřej ; Hes, Ondřej (advisor) ; Mandys, Václav (referee) ; Ehrmann, Jiří (referee) ; Zámečník, Josef (referee)
Daum O., Grossmann P., Vanecek T., Sima R., Mukensnabl P., Michal M. (2006): Diagnostic morphological features of PDGFRA-mutated gastrointestinal stromal tumors: Molecular genetic and histological analysis of 60 cases of gastric GISTs. Ann. Diagn. Pathol. In Press Summary In this study, 60 gastrointestinal stromal tumors (GISTs) of the stomach were analyzed to elucidate the possible relation of their morphology to mutation status of KIT and PDGFRA genes. The patients included 27 men and 33 women with a mean age of 63,8 years (range 12 to 92). Only one tumor occurred before the age of 21 years. KIT mutations were detected in 31 cases (51,7%), PDGFRA mutations in 22 cases (36,7%), and seven cases (11,7%) were KIT and PDGFRA wild type. When the mutation status was correlated with histological features of the tumors, epithelioid or mixed epithelioid/spindle cell pattern and mast cell infiltration were found as the most reliable signs of PDGFRA mutation. Neoplastic rhabdoid cells and multinucleated giant cells, also previously reported as features of PDGFRA mutated GISTs, seemed to be less specific but still helpful markers in our study. Finally, tumor infiltrating lymphocytes and myxoid stroma do not seem to be valuable histological signs. Daum O., Klecka J., Ferda J., Treska V., Vanecek T., Sima R., Mukensnabl...

Freestyle skiing, New School.
Kopal, Jan ; Finková, Dana (advisor) ; Matošková, Petra (referee)
Univerzita Karlova v Praze, Fakulta tělesné výchovy a sportu Abstrakt Název práce: Freestylové lyžování, New School Freestyle skiing, New School Cíle práce: 2 Vytvořit komplexní pohled na New school freestylové lyžování a pomocí literární rešerše popsat problematiku freestylu ve vybraných oblastech. Metoda: Při řešení byla použita rešeršní metoda analýzy dokumentů, které se zabývají freestylovým lyžováním. Výsledky: Byl vytvořen ucelený pohled na problematiku New School freestylového lyžování. Vznikla tak práce, která se komplexně zabývá vznikem a vývojem New School ve světě a v ČR, freestylovými disciplínami, materialním vybavením a lyžařskými lokalitami pro freestyle. Klíčová slova: Freestyle, New School, freeskiing, lyžování, lyže.

Space (in) film: theoretical conceptions of space from reality to intermedia
Svatoňová, Kateřina ; Hanáková, Petra (advisor) ; Bílek, Petr (referee)
FILOZOFICKÁ FAKULTA UNIVERZITY KARLOVY V PRAZE KATEDRA FILMOVÉ VĚDY PROSTOR (VE) FILMU teoretické koncepce prostoru od reality k intermedialitě Diplomová práce VEDOUCÍ PRÁCE KATEŘINA SVATOŇOVÁ PhDr. PETRA HANÁKOVÁ, Ph.D. PRAHA 2006 2 Prohlašuji, že jsem diplomovou práci vypracovala samostatně s využitím uvedených pramenů. Upřímně děkuji1 Petře Hanákové, Ph.D. za velice moudré a inspirativní vedení napříč časoprostorem a svému otci za to, že tato procházka od reality k intermedialitě mohla být takto příjemná. 1 Stejně jako není možné uchopit problematiku prostoru v celé jeho šíři na rozměru diplomové práce, není ani adekvátní a zcela výstižné takto strohé poděkování... 3 OBSAH: Úvod I. Záměry a cíle diplomové práce. Struktura tématu 5 II. Metody a současný stav bádání 10 Prostor a jeho možná vymezení I. Žitý prostor 12 I.1. Filozofické koncepce prostoru 19 I.2. Prostor jako antropologická kategorie a jeho vnímání 22 I.3. Problematika času a prostoru v jednotlivých teoretických konceptech 31 II. Mimetický prostor 38 II.1. Transformace prostoru médiem a jeho abstraktní chápání 39 II.1.1. Prostor díla 48 I.1.2. Prostor v díle 65 II.2. Problematika času a prostoru v mimetických uměních 74 Prostor jako komunikace, prostor jako narace III.1. Vývoj naratologických konceptů směrem k prostorovosti 91 III.2. Prostor...

Provincial town, culture and etnography
Jeníčková, Kateřina ; Sochorová, Ludmila (referee) ; Štěpánová, Irena (advisor)
Eleonora and Marie Prosek were the teachers and ethnography research workers, which on the break 19 and 20 century worked in Turnov. Their fates show us what acceptance had ideas of women emancipation among active women in small provincial town. Their interest in ethnography show us beginning of ethnography as a scientific branch and what importance had women in that. Eleonora was born on 13 th December 1844 in Prague and Marie was born on 10 th February 1858 also in Prague. Sisters obvious come from family, which came under the middle classes. In Prague sisters attended the school. Sisters were venerable much distant and so possibilities of education they had different. Eleonora gained education of teacher of needlework, but Marie was able to gain education on school for teachers and started to teach also specialist subjects. To Turnov came Eleonora in 1872 and started to teach needlework on school for girls. In this time she was interesting of national dresses and textile. This interest she specified from 1886 in cooperation with museum in Turnov. She cooperated also on preparation on big exhibitions in 90. 19 century, which took place in Prague. She completed national dress of Turnov and lake the first she described national dress of Turnov, which retained in 80. 19 century. With museum she cooperated to...

Documents about North America's cultures in collection of the Library of Naprstek's Museum
Kochová, Eva ; Stöcklová, Anna (advisor) ; Khel, Richard (referee)
Cílem práce je popis a analýza fondu Knihovny Náprstkova muzea z hlediska významu pro studium severoamerických kultur. Zahrnut je i životopis Vojty Náprstka jako zakladatele Náprstkova muzea a muzejní knihovny, s rozhodujícím vlivem na jejich vznik, vývoj a zaměření, čímž se v důsledku stala Knihovna Náprstkova muzea jedinečným zdrojem dokumentů o severoamerických kulturách na území České republiky. Práce je věnována dokumentům o severoamerických kulturách v historickém, speciálním i současném fondu knihovny, s přihlédnutím k jejich významnosti, či specifickým hodnotám. Na základě těchto dokumentů byla vytvořena i kapitola o významu severoamerických kultur, jakožto vyměření předmětu citovaných a popisovaných dokumentů. [Autorský abstrakt].

Possibilities and ways, how to prolong or hold our quality of life
Papežová, Klára ; Bártová, Jiřina (advisor)
The subject of the submitted dissartation is a psychological and sociological analysis of an ageing population problem. The work deals with various options of an active approach that senior citizens could enrich their futher way of life and it offers opportunities of specific involments for elderly people, including the possibility of proposed study at University of the Thirt Age (U3A). The research also includes a pilot project on a selected group of senior citizens - students of Charles University, 3rd Medical Faculty in Prague.

Problems of biocompatibility in renal replacement therapy
Polanská, Kamila ; Opatrná, Sylvie (advisor) ; Tesař, Vladimír (referee) ; Mydlík, Miroslav (referee)
.Summary 7.1. The effect of heparin rinse on selected biocompatibility parameters in continuous extracorporeal renal replacement therapy methods In her study assessing the effect of heparin on biocompatibility parameters in continuous renal replacement therapy methods, the author has made the following conclusions: 1) Patients scheduled for CVVHDF show comprehensive hemostasis impairment involving thrombocyte activation, coagulation, and fibrinolysis. 2) These patients show, already prior to CVVHDF initiation, signs of activation of complement with high C5a levels and, also, high leukocyte count compared with a control group of healthy individuals. 3) Preparation of the extracorporeal circuit before CVVHDF using various techniques of rinse (heparin-free saline, saline with 2,000 IU heparin/L and one-hour saline rinse using 10,000 IU heparin/L with recirculation) has no effect on the behavior of thrombogenicity parameters, complement activation and leukocyte count during CVVHDF and will not reduce the consumption of anticoagulants administered. Hence, it can be concluded that heparin rinse of the extracorporeal circuit prior to CVVHDF initiation will confer no benefit in terms of reduced thrombogenicity, need for anticoagulants, and elimination of the adverse effect of the artificial surface on the other...

Catalogue of school chemical experiments on topic catalysts
Novotný, Petr ; Banýr, Jiří (referee)
Práce předkládaná k rigoróznímu řízení navazuje na mou diplomovou práci - "Kartotéka školních chemických pokusů - téma katalyzátory", obhájenou v červnu roku 2004 ve studijním oboru učitelství chemie a biologie pro II. stupeň základních škol a střední školy, Pedagogická fakulta Univerzity Karlovy v Praze. Z fakulty jsem si do svého současného zaměstnání - učitel chemie a přírodopisu na ZS odnesl chuť pokračovat v započaté práci a rozvinout kartotéku do kvality, která by se dala označit jako profesionální. Powered by TCPDF (www.tcpdf.org)