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Ilja Zeljenka and his Organ Activity
Zaťková, Iveta ; Černý, Pavel (advisor) ; Tůma, Jaroslav (referee)
Ilja Zeljenka was one of the most impressive Slovak composers generation, which formed under the influence of musical classics of 20th century and European avant-garde in 50s and 60s. His work of art was distinctly style individualized since the first opuses. In forming of Z´s musical accent there are several notable aspects - from neoclassicism (which became the basis of his next creation), across postweber concepts, influence of New (Age?) music and expressionistic features of the 60s to folklore-inspired creation and neo-romantic orientations in the 70s. Getting beyond tradition in effort of colorful expressive nuances, IZ sketched new sound temper and form, and that´s why his music was so popular in Slovakia, but also in abroad. For his production he was awarded with several domestic and foreign prizes. I divided my work into multiple chapters, starting with CV, compositional development of his work and focusing on analysis of his organ composals.

Accents of Social Work of Police Officers
SITTER, Pavel
Every police officer goes through a variety of different situations during his/her working day, out of which social contact and communication with other people forms the largest percentage. The profession of police officer is unique and performance of its duties brings with it increased demands on the personality of each police officer in many aspects. Regardless of the official position, rank or place of work, the common basis of the police profession is work with people and information. Mastering the general principles of successful communication and basic communication principles, together with understanding the main causes of communication disagreements, is good communication equipment, which can be applied in everyday communication with others, as well as in professional communication. The aim of this thesis was to determine how members of the traffic police manage aggression of road users towards them if they are subject to punitive measures, whether in dealing with participants of road accidents use haptics as a means of understanding, comprehension or expression of belonging and what they imagine under the slogan "To help and to protect." This thesis is divided into a theoretical and a practical part. The theoretical section provides information on laws and regulations regarding the scope of work and activities of the Police of the Czech Republic with theories and examples of appropriate communication. The practical part presents results of quantitative research through questionnaire survey and results of qualitative research using methods of case report. The research results showed that the traffic police officers would be interested in improving assertive techniques, focusing on good communication to manage aggressive behaviour of road users. It is a challenge for police training centres.

Effect of stress on corticosteroid metabolism in peripheral tissues
Makal, Jakub ; Pácha, Jiří (advisor) ; Vybíral, Stanislav (referee)
Stressor influence can lead to homeostatic disruption. To eliminate this threat, mechanism which compensates negative effects of stressor was evolved by organisms. It's called stress response. One of two major systems that moderate stress response of organism is hypothalamic- pituitary-adrenal axis (HPA axis). Effectors of the HPA axis are glucocorticoids, steroid hormones secreted from adrenal glands. Enzymes which metabolize glucocorticoids are located in target tissues for these hormones. They convert active glucocorticoids into their inactive forms, or vice versa. Untill now, two such enzymes have been described - 11beta-hydroxysteroid dehydrogenases type 1 and type 2. It was proved that expression and activity of these enzymes can change under the influence of stressor. These changes are tissue-specific and dependent on type of applied stressor.

Hate speech in the Czech legal theory and media practice
Moravová, Veronika ; Křeček, Jan (advisor) ; Štechová, Markéta (referee)
This bachelor thesis deals with the topic of "hate speech" in relation to the freedom of expression. In the first part, I went into the legislation on freedom of expression and hate speech in our legal system. I devoted a considerable part to international treaties concerning this issue that, according to the Constitution, are a part of our laws and base of the national legislation to a great extent. There are two different approaches to the freedom of expression - the American and European one. The first one is close to the absolute concept of freedom of speech that also covers the hate speech. The second one excludes the hate speech from its protection. The most typical representatives of these two approaches are the U.S. and Germany so I have also paid attention to the legislation of the two countries. As this topic is extremely wide, I chose for the practical part a few cases that are somehow boundary. With the aid of these extremes, I tried to define the limits of freedom of speech. In the next two subsections, I tried to reflect two controversial lawsuits medially, i.e. the Mein Kampf edition and the visit of David Duke in pages of the Lidové noviny, Právo and MF Dnes. The next subsection is devoted to the Internet, beyond the territory of states, so, logically, there is a collision between...

President Masaryk as an anonymous journalist (1918-1935)
Vašek, Richard ; Kvaček, Robert (advisor) ; Harna, Josef (referee) ; Galandauer, Jan (referee)
This thesis focuses on the literary and journalistic works of Czechoslovakia's first president, Tomáš Garrigue Masaryk - how he attempted to influence public opinion through them and entered into the current disputes on various topics. The main interest of this thesis is his anonymous journalistic output, i.e. articles and commentaries that he wrote under different initials, or were published anonymously. In these writings, Masaryk continued his previous wartime and pre-war activities. After the war, however, they took on completely different proportions since he couldn't remain a purely private person. He was seen primarily as the head of the state. His political function thus began to intersect with his tendency to express his opinions on various topics in public and enter into the current political and cultural arena. Masaryk tried to overcome (or circumvent) this contradiction, which was limited by the formal delimitation of the powers of the president of the republic, by publishing anonymous articles. In these texts he could express hismelf more freely and openly than he could in signed articles or official speeches. The goal of this thesis is not only to capture and collect, but also to analyze and interpret the president's output, including the description of the background and the...

The hereditary sensomotoric neuropathy.
Jelínková, Zora ; Daňková, Pavlína (advisor) ; Šolc, Roman (referee)
Hereditary motor and sensory neuropathy (in short HMSN or hereditary sensomotoric neuropathy) also known as Charcot-Marie-Tooth disease (CMT) is a clinically and genetically heterogeneous group of diseases which are the most frequent disorders affecting peripheral nervous system. The prevalence of these illnesses is generally 5 - 40 people per 100 000 inhabitants. CMT was first described in the 1886. Because of a large number of various types of mutations classification of HMSN is disunited. The main division of CMT depends on the median motor conduction velocity (and also on the part of nerve that was damaged). It is demyelinating (CMT 1) type and axonal (CMT 2) type. Further classification depends on the mode of heredity and phenotypic expression. Autosomal dominant CMT are divided into four main types - CMT 1A to D. Similar, CMT 2 could be distinguished by genetical subtype as well or, the classification can follow phenotypic expression. Beside the autosomal inherited HMSN, other types of hereditary sensomotoric diseases do exist: intermediate CMT, X-linked CMT, Déjerine-Sottas syndrom, congenital hypomyelination neuropathy and hereditary neuropathy with liability to pressure palsy. Individual types of HMSN are caused by mutations in various genes that are localized on different chomosomes. The...

Specific theories of private property in the economic thought of XIX century: the Manifesto of the Communist Party versus Rerum Novarum
Šárková, Kristýna ; Vyhnánek, Tomáš (advisor) ; Skuhrovec, Jiří (referee)
The bachelor thesis compares the Catholic and Marxist understanding of private property as expressed in Rerum Novarum and the Manifesto of the Communist Party. The situation of the lowest class had demeaned during the 19th century to such a level that a large part of society had to face an existential crisis. A continually decreasing wage, alarming working conditions, the non-existence of social security and a high unemployment rate were characteristic for the 19th century. With the rise of mechanical production women and children started playing an active part in the working process, thus escalating the competition on the labour market. Karl Marx's solution written down in the Manifesto was based on abolishing private property and allocating it under collective keeping. On the contrary, the Catholic Church insisted on maintaining private property and emphasized solidarity among social classes. The Church's reaction to the condition of the lowest class and the growing support of communism in Europe was formulated in the first social encyclical Rerum Novarum. The thesis compares both views involved through describing the historical background and understanding of property. The rest of the work deals with a more detailed analysis of the Catholic point of view, followed by a discussion of the application and...

Criticism of Social Conditions in the Drama of F. G. Lorca, A. Casona, R. Alberti and M. Mihura
Lukešová, Alice ; Sánchez Fernández, Juan Antonio (advisor) ; Mathé, Lukáš (referee)
This thesis is concerning four playwriters: Lorca, Casona, Alberti and Mihura. Although it is not common to discuss them together, selected authors were born, grew up and started to write their plays in the same period, influenced by the very same events. Thus they use their works to reflect the same social issues. Every author expressed his criticism by specific forms: tragedy, absurd comedy, avant-garde or poetic theater. The variety offered in their works enables to illustrate the society from different points of views, which can hence capture it as a whole. Fancy and interpretation differ widely among people, therefore criticism expressed through various forms, is supposed to interest a wide range of persons.

Evaluation of Jan Fischer's Cabinet
Červenka, Jan
In January survey CVVM focused on evaluation of Jan Fischer's government. 75 % of Czechs are satisfied with the person of Prime Minister, 17 % are dissatisfied, 66 % are satisfied with government's performance and 24 % are not. Also government's program (56 % / 24 %) as well as communication with public (56 % / 29 %) is evaluated predominantly positively. 48 % of respondents see positively also a personal composition of Fischer's government, 35 % expressed opposite feeling in this matter.

The Development and Validation of HPLC Methods for Determination of Ketoprofen in Pharmaceutical Preparations
Bajcurová, Lucie ; Matysová, Ludmila (advisor) ; Chocholoušová Havlíková, Lucie (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Mgr. Lucie Bajcurová Consultant: PharmDr. Ludmila Matysová, Ph.D. Title of Thesis: The Development and Validation of HPLC Methods for Determination of Ketoprofen in Pharmaceutical Preparations The already developed method for determination of ketoprofen in the pharmaceutical preparation "PRONTOFLEX" - a 10% skin spray has been validated. The precision expressed as relative standard deviation was 1.43 %. The accuracy expressed as recovery was 101.52 %. The correlation coefficient R was more than 0.999. The method for determination of ketoprofen in the pharmaceutical preparation "Ketonal" - a 5% cream has been further developed. The already developed method has been validated. The chromatographic separation was performed on a SUPELCO Discovery C18 column (150 mm x 4.6 mm, 5 µm). The mobile phase consisted of a mixture of acetonitrile, water and a phosphate buffer pH 3.5 (39:59:2, v/v/v). At a mobile phase flow rate of 1.5 ml/min, injection volume of 5 μl and UV detection at a wavelength of 233 nm, the total time of analysis was less than 10 minutes. Ethylparaben was used as an internal standard. The precision expressed as relative standard deviation was 0.64 %. The accuracy expressed as...