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Importance of communication elements for management
Holeček, Petr ; Fiedler, Jiří (advisor) ; Stanislav, Stanislav (referee)
The thesis deals with communication in managerial practice. The aim is to identify the importance managers attach to specific elements of communication. Each of us sees communications as natural and normal activity. However, communication should always correspond to what purpose is served and what style should be used. In conjunction with the management of activities is already communicating on a higher level with its specific aspects. Now setting effective communication is essential for the operation of the company, which alone can compete. Communication is also also an important part of company activities, since it is managerial communication significantly affects not only the prosperity of the company and its operations, but also employee satisfaction and the ability to motivate and to achieve the goals. Managerial communication also helps to manage communications managers and develop their skills. Outputs, which can be obtained by processing data can serve seam managers involved in the research, using data which we obtained via questionnaire. They can then apply not only in their work but also for other workers in the company.
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Quantitative analysis of D2 dopamine receptors in clinically non-functioning pituitary adenomas
Gabalec, Filip ; Čáp, Jan (advisor) ; Fryšák, Zdeněk (referee) ; Hána, Václav (referee)
Quantitative analysis of D2 dopamine receptors in clinically non-functioning pituitary adenomas Introduction Clinically non-functioning pituitary adenomas account for about one-third of pituitary tumors. The majority of them are pathologically classified as gonadotropinomas or null-cell adenomas without hormonal expression. The rest represent silent corticotroph adenomas and plurihormonal tumors. Conservative therapy with dopamine agonists is effective in some cases only depending on the expression of dopamine 2 receptors (D2R). Objective The aim of this study was to quantitatively estimate D2R expression in clinically nonfunctioning pituitary adenomas and correlate the results with adenoma type according to pathological classification. Methods and results Out of the 87 adenomas investigated, 63 expressed gonadotropins, 7 were silent corticotroph adenomas, 7 were plurihormonal tumors, and only 6 did not express any pituitary hormone on immunohistochemical investigation. With the use of the reverse transcriptase real-time PCR technique, D2R mRNA was expressed in all adenomas with very heterogeneous quantity. The expression was very low in corticotroph adenomas (relative median quantity after normalization to housekeeping gene 0.01) and lower in plurihormonal tumors (median 0.4) than in gonadotroph...
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Foreign exchange risk management in the company IMP Jablonec
Vaculík, Martin ; Taušer, Josef (advisor) ; Nývlt, Daniel (referee)
The diploma paper offers a complex view on hedging of a foreign exchange risk in a concrete company, which is highly dependent on export. Preliminary theoretical part sums up all the possibilities how to avoid risk, including hedging or financial derivatives. Specific attention is paid to in practise always more popular option strategies. Practical part then try to apply all the acquired knowledge on a concrete company. After the complex analysis of revenues and expenditures is presented analysis and evaluation of the whole hedging strategy.
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Divergent organohalide-respiring consortia in PCB-contaminated sediments
Mikešová, Martina
This study is focused on one particular group of the halogenated molecules called polychlorinated biphenyls (PCBs) - synthetic, organic compounds derived from biphenyl with bound chlorine atoms. Depending on the position and number of the chlorine atoms, there are theoretically 209 individual PCB congeners. Although PCBs production was brought to a halt thirty years ago, recalcitrance to degradation makes them a major environmental pollutant at a global scale. Large amounts of PCBs were produced in several countries, and former Czechoslovakia belonged to the ten major world producers. Despite the PCB congener resistance to chemical modification, bacterial process of reductive dechlorination, named organohalide respiration (OHR), was shown to be efficient in the dechlorination of extensively chlorinated PCB congeners and a prerequisite step towards their subsequent complete mineralization by aerobic bacteria. In our study, reductive dechlorination of polychlorinated biphenyls (PCBs) was assessed using long term anaerobic microcosms. The microcosms were inoculated with highly contaminated with weathered Delor sediments, sampled from the efflux channel of the former PCB manufacturer Chemko Strazske. After one year of cultivation the chemical analysis showed a degradation of up to 36 % of the highly...
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Glycophenotype of head and neck carcinomas
Chovanec, Martin ; Smetana, Karel (advisor) ; Mandys, Václav (referee) ; Martínek, Jindřich (referee)
1 THESIS The thesis deals with the glycophenotype analysis of normal squamous cell epithelia, and head and neck squamous cell carcinomas. Many research projects focus on improving patients prognosis studying biological properties of the tumor. The alterations of carbohydrate motives occur during cell differentiation and carcinogenesis. Lectins are proteins that bind to specific carbohydrate structures. Animal lectins, including human lectins, consist of five subfamilies according to their binding specifity. Much attention is paid to the investigation of galectins - -galactoside binding proteins. Their carbohydrate recognitive function is not dependent on the presence of Ca2+ ions, contrary to the other lectin types. Galectins play important roles in many biological processes, e.g. in adhesion, intercellular interactions, immunomodulation, inflammation, cell growth, apoptosis, pre-mRNA splicing. Alterations in any of these might contribute to the malignant transformation and cancer progression. Endogenous lectins (galectins, Langerin, Manose receptor) were detected using immunohistochemistry, galectin-binding sites were localized by lectin histochemistry. Reverse lectin histochemistry was employed for the study of glycosaminoglycan binding sites. Human (squamous cell epithelia of the oral cavity, oropharynx...
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International economic organizations and impact of their activities on international trade development
Jovičić, Elena ; Sato, Alexej (advisor) ; Štěrbová, Ludmila (referee) ; Čajka, Peter (referee)
The necessity for a more adequate regulation of global trade relations (including support for the liberalization and development of international trade), in the context of the deepening globalization processes, requires a greater level of involvement of international economic organizations and more effective implementation of their activities. The primary purpose of the dissertation is to determine whether and how the World Trade Organization, the United Nations Conference on Trade and Development, the International Monetary Fund and the World Bank Group have influenced the development of international trading system. The results of this thesis show that international organizations (primarily WTO and UNCTAD) during various stages of its development have been significantly affecting international trade growth mainly through the implementation of specific activities and measures related to a series of agreements and decisions. However, international organizations have had a divergent impact on international trade. The effectiveness of the implementation of specific activities and programs were depending on the political and economic situation of member countries, as well as the governments´ readiness and willingness to implement these measures. On the other hand, the effectiveness of realization of specific activities have been affected by either the internal weaknesses of the organizations, or the insufficient level of cooperation and coordination in the implementation of joint programs and measures aimed at international trade development.
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Consequences of assumption violations of selected statistical methods
Marcinko, Tomáš ; Blatná, Dagmar (advisor) ; Malá, Ivana (referee) ; Lukáš, Ladislav (referee)
Classical parametric methods of statistical inference and hypothesis testing are derived under fundamental theoretical assumptions, which may or may not be met in real world applications. However, these methods are usually used despite the violation of their underlying assumptions, while it is argued, that these methods are quite insensitive to the violation of relevant assumptions. Moreover, alternative nonparametric or rank tests are often overlooked, mostly because these methods may be deemed to be less powerful then parametric methods. The aim of the dissertation is therefore a description of the consequences of assumption violations concerning classical one-sample and two-sample statistical methods and a consistent and comprehensive comparison of parametric, nonparametric and robust statistical techniques, which is based on extensive simulation study and focused mostly on a normality and heteroscedasticity assumption violation. The results of the simulation study confirmed that the classical parametric methods are relatively robust, with some reservations in case of outlying observations, when traditional methods may fail. On the other hand, the empirical study clearly proved that the classical parametric methods are losing their optimal properties, when the underlying assumptions are violated. For example, in many cases of non-normality the appropriate nonparametric and rank-based methods are more powerful, and therefore a statement, that these methods are unproductive due to their lack of power may be considered a crucial mistake. However, the choice of the most appropriate distribution-free method generally depends on the particular form of the underlying distribution.
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Social Business of NGOs
Nováková, Anna ; Krbová, Jana (advisor) ; Dvořák, Jiří (referee)
The subject of the thesis is the proposal of the work integration social enterprise (WISE) of NGO SOS Children's villages. Proposal shall take form of a business plan and is based on the needs of the Association to reduce its financial dependence on an external sources of funding. A business plan is a proposal of the concrete WISE which fulfils the function of an alternative financing instrument for the main activities of the Association. The thesis uses the method of SWOT analysis to group and evaluate the available information from the external and internal environment of the WISE as well as uses tools of economic and financial analysis to determine the tipping point and the financial needs for the operation of social enterprise in the first three years of operation. The thesis brings new results and knowledge and proposes a recommendation of how the social enterprise could be realized.
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Econometric analysis of the determinants of demand for coffee in Czech Republic
Brummerová, Zuzana ; Čechura, Lukáš (advisor)
The Econometric analysis of the determinants of demand for coffee in Czech Republic assesses the impact of selected factors on coffee consumption in the selected period. The thesis is devided into two main parts. The first theoretical part describes the general character of econometric analysis, its goals and its partial methods. This part also discusses the characteristics of the analyzed commodity and it is coffee. The second practical part assesses what factors significantly affect the consumption of coffee, determines dependence of coffee consumption on the determinants of demand and finally derives forecasts of coffee consumption in future periods.
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