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Analysis of consumption of antibiotics in patients treated with dialysis
Ždímalová, Radka ; Vlček, Jiří (advisor) ; Matoulková, Petra (referee)
1. ABSTRACT Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of social and clinical pharmacy Candidate: Ždímalová Radka Supervisor: Prof. RNDr. Jiří Vlček, CSc. Title of rigorous Thesis: Analysis of consumption of antibiotics in patients treated with dialysis Introduction and objective: This study observes consumption of antibiotics in patients treated with dialysis in The University Hospital of Hradec Králové in years 2006 and 2007. Pilot project investigate, which kind of antibiotics used dialyzed patients (DP) the most of all. Studies further compare information from two sets of DP from Czech Republic (Group I) and Lithuania (Group II) in specific aspects of antibiotic's consumption. Methodology: Retrospective analysis resulting from data evaluation from Nephris database of University Hospital of Hradec Králové by DP (2006&2007). Set of data of the Group II from Clinics of Kaunas Medical University - Lithuania was process by retrospective analysis too. GLMZ mode was used for statistical analysis. Results: Group I: from average number of 125 hospitalized patients were treated by antibiotics 71 (57%) patients. Both men and women have the same representation in the group, patients undergoing dialysis mostly in higher age, what has been discovered by mean age 66 years. From 71...
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Evaluation of force presumptions for swimming triathletes from Czech team in training cycle 2009-2010
Švejda, Roman ; Horčic, Josef (advisor) ; Kovářová, Lenka (referee)
Title: Evaluation of force presumptions for swimming triathletes from Czech team in training cycle 2010-2011 Intention of work: Evaluation of specific force presumptions for swimming and ability maximal utilit force efficiency in long time stress, wide spektrum of triatlonist from beginners to elite czech competitors. For evaluation we used 3 indikators: 1. average Power Output - PO - [W] 2. average power output on kg body weight - PO.kg-1 - [W.kg-1 ] 3. complete work - W - [Nm] Method: Testing on swim trainer Biokinetic by tests which simulated free style strokes and butterfly strokes. 10 strokes by free style and butterfly styl, 50 and 100 strokes by butterfly style. Results: Some people lives in mistake about their directionality. Someone think, that he is better for long distance, and oposit eis true. Lot of people, in our test, made more work [Nm] in free style strokes, than butterfly strokes. More offen people made more work [Nm] in butterfly strokes. Our people swim butterfly just especialy and that's the reason, why they have more force in crowl. Keywords: Biokinetic, triathlon, swimming, testing, swim force.
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Využití odpadů na pile v Prusinovicích
Měrka, Tadeáš
This work compares the possibilities of use of wastes and proposes a method of its use, suitable for the conditions of the sawmill in Prusinovice. It based on from the total volume and ranges of processed material with representation individual ranges produced lumber, technological flow of production and achieved yield. It focuses on all types of wastes generated during the production, their place of origin, volumes, character, features and usability. At the same time focuses on the species of timber drying kilns, a range of sizes and types of dried lumber and its input and needed output moisture. It sets the average consumption of heat per unit volume of dry timber for its main product and for the type of drying kilns, the heat consumption for heating buildings of plant and the amount of heat that can be obtained by incineration of wastes. It sets options cover the energy needs of the plant and the possibilities of sale or buying individual types of waste, including the treatment. The work proposes alternatives of use of sawmill wastes for heating and drying timber in the sawmill in Prusinovice, evaluates and recommends optimal variant.
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Rationaly Aspectof Antibioticotherapy in Patients treated with Dialysis.
Vrběcká, Radka ; Vlček, Jiří (advisor) ; Zemková, Marcela (referee)
Ždímalová R.: Analysis of consumption of antibiotics in patients treated with dialysis, Charles University in Prague, Faculty of Pharmacy, Department of social and clinical pharmacy, Hradec Králové 2009, 73 pages. Introduction and objective: This study observes consumption of antibiotics in patients treated with dialysis in The University Hospital of Hradec Králové in years 2006 and 2007. Pilot project investigate, which kind of antibiotics used dialyzed patients (DP) the most of all. Studies further compare information from two sets of DP from Czech Republic (Group I) and Lithuania (Group II) in specific aspects of antibiotic's consumption. Methodology: Retrospective analysis resulting from data evaluation from Nephris database of University Hospital of Hradec Králové by DP (2006&2007). Set of data of the Group II from Clinics of Kaunas Medical University - Lithuania was process by retrospective analysis too. GLMZ mode was used for statistical analysis. Results: Group I: from average number of 125 hospitalized patients were treated by antibiotics 71 (57%) patients. Both men and women have the same representation in the group, patients undergoing dialysis mostly in higher age, what has been discovered by mean age 66 years. From 71 patients treated with antibiotic was prescribed the most of all...
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Potentionalities of research of individual performance factors in defensive play in youth categories
Chotěborský, Jan ; Perič, Tomáš (advisor) ; Koňák, Luboš (referee)
Appellation of thesis Potentionalities of research of individua! performance factors in defensive play in youth categories. Aim of thesis The ai.m is to compose the profile of individua! performance in defensive play in elderly youth categories at somatic and fitness factors. Solution methods Examined sample of inquired population was represented by following spectrum of players who we tested. Test form 6th class I nr.p. 7th class I nr. p. 8th class I nr. p. 9th class I nr. p. Nonspecific 24 25 22 18 Specific 21 25 20 17 Total quantity of 45 50 42 35 players Players were devided into two performance categories according to achieved results. In each age category we branded the elite peďormace category which is represented by 85-95 percentile according to achieved results. The other players who achieved the results in range 40-60 percentile we braded as average performance category. Th results of this category is labled as middle value (SH). Results Statistically significant diffemces in results as the age, body weight, body height, cardio endurance capability, speed abilities, muscular power abilities, co-ordination abilities and flexibility, which determine individua! performance in defensive play we registred according to: The age The Performance - elite and average Keywords The age category,...
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Does appreciation of the Czech crown lead to growth of the unemployment rate in the Czech Republic?
Svobodová, Lucie ; Mičúch, Marek (advisor) ; Lahvička, Jiří (referee)
The paper investigates the impact of changes in the exchange rate of the Czech crown against the Euro on the rate of unemployment in the Czech Republic. The survey is using time series from 2000 to 2010 and there are used two models. A brief theoretical framework discusses several papers on this topic. The results of empirical testing confirm the hypothesis of the work. Appreciation of the Czech crown against the Euro by 1 crown causes an increase in the unemployment rate by 0.028% and by 0.023% with inclusion of average real wage into the model. Moreover German GDP, Czech import, labour productivity and average real wage have statistically significant effect (at least on the 10% significance level) on the growth of unemployment.
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Epidemiological trends of treatment benign prostate hyperplasia.
Němečková, Eva ; Hochmann, Jiří (referee) ; Semecký, Vladimír (advisor)
Epidemiological trends of treatment benign prostate hyperplasia Background: The purpose of the work was to follow up trends of treatment benign prostate hyperplasia (BPH) in Czech Republic. The aim of second part was to review the registered alpha-blockers and finasterides in Czech Republic from 1997 to 2008. The last part compares the expenses for transurethral resection of the prostate (TURP), transvesical prostatectomy (TVPE) and the annual treatment with tamsulosin in Slovakia, Poland, Germany, Austria and the United States of America. Methods: The first part is based on data provided by the Urological Clinic of Faculty hospital in Hradec Králové for the decade 1997 - 2007. An increase was observed of the number of patients and the medical therapy and a fall of the surgical therapy of TURP and TVPE. Financial charges were based on informations from foreign clinics and articles. Results: The number of patients with BPH increased from 1624 in 2003 to 2140 in 2007. There were on average 2491 prescriptions per year and the number of patient's visits was 2,12. TURP was practised more on the clinic. The percentage of patients with TURP decreased from 11,76 % to 5,47 % in years 2003 to 2007. TVPE fell from 1,24 % in 2006 to 0,56 % in 2007. The number of registered alpha-blockers increased from 5 to...
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Evaluation of transdermal permeability of folic acid using methylparaben as marker.
Kubíková, Kateřina ; Berka, Pavel (advisor) ; Doležal, Pavel (referee)
In the theoretical part, there is briefly described the problematic of skin in the connection with transdermal permeability of substances. This part is followed by a general summary about transdermal permeability testing. Further on there were described the basic features of methylparaben and folic acid as substances used for permeability tests. Experimental part of the diploma thesis describes the testing conditions for in vitro testing of permeability of methylparaben and folic acid from the TRIS buffer, the TRIS buffer with propylene glycol (PG) (3:2), isopropyl myristate (IPM) and isopropyl myristate (IPM) with parafin oil (PO) (2:3) through the full thickness pig ear skin. Measured values of normalized fluxes of folic acid JKLn were as follows: from TRIS buffer: 1,00 ± 0,47, RSD 46,5%; from TRIS buffer with PG: 0,28 ± 0,11, RSD 40,1%; from IPM: 0,86 ± 0,72, RSD 83,4%; from IPM and PO: 2,08 ± 3,91, RSD 188,2%. The following average ratios of folic acid normalized fluxes and methylparaben normalized fluxes JKLn/JMPn from separate donors (and their standard devations and relative standard deviations) were obtained: from TRIS buffer: 0,98 ± 0,46, RSD 46,3%; from TRIS buffer with PG: 0,18 ± 0,09, RSD 52,2%; from IPM: 0,78 ± 0,77, RSD 98,9%; from IPM and PO: 1,76 ± 2,86, RSD 162,4%. The conclusion...
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The analysis of management of dyslipidemia by outpatients in 2002-2007
Lancmannová, Lenka ; Vlček, Jiří (advisor) ; Malý, Josef (referee)
The analysis of managment of dyslipidemia by outpatients in 2002 - 2007 Student: Lenka Lancmannová Dissertation supervisit: Prof. RNDr. Jiří Vlček, CSc Training Specialist: Mgr. Martin Doseděl Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec kralove, Charles University in Prague, Czech Republic Introduction: Atherosclerosis and the resulting cardiovascular disease (ICHS, IM, ICHDK, CMP) are the main cause of morbidity and mortality of adult population in developed countries. The introduction of lipid lowering medicaments in clinical practice is one of the most therapeutic procedures affecting the prognosis and quality of life of patients Aim: Monitoring during treatment of patients with dyslipidemia, standardization of lipid levels, achieving the targets in the blood lipid levels. Monitoring prescription lipid lowering in the years 2002-2007 Methods: 177 patients were monitored (92 men, 85 women, average age 59 years) in the form of retrospectives, the period of 5 years. Data were drawn from the records from 3 patients of general practitioners and 1 internists. Results: The largest representation of patients have the mixed dyslipidemia, 91%. Most patients fell within the primary prevention of 54,2%, in secondary prevention 28.8% in secondary prevention with DM2 type 6.2%,...
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Testing of methods of the technical analysis on foreign exchange market
Rajča, Tomáš ; Taušer, Josef (advisor) ; Žamberský, Pavel (referee)
This thesis is focused on selected methods of the technical analysis and their application on foreign exchange rate. The goal is to evaluate the usability of individual methods in the field of foreign exchange market. The main emphasis is on moving averages, but also other methods are tested. For the purpose of evaluation is used the profitability of tested methods or other suitable characteristics. The methods of technical analysis are theoretically described in the first part of this thesis and in the second part follows their testing with the use of real data and the evaluation of their performance.
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