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Prevention of the mother to child transmission of HIV infection with emphasis on brestfeeding
Gojdič, Matej ; Schneidrová, Dagmar (advisor)
The issue of transmission of HIV infection from mother to child is Currently, a high current . Testify statistical Data from WHO . By 2007 , the infected up to two and a half million children in the same year were added 420,000 new children's cases . The sad fact is, in particular , that the Already succumbed to AIDS 330,000 children and the death toll continues to increase steadily . One objective of my work was summarized by available knowledge of the possibilities of vertical transmission of HIV , with an emphasis on breastfeeding on the factors affecting the transmission and the degree of risk for the child . In addition, efforts trying sprehľadniť international , governmental and non-governmental organizations in the fight against transmission of HIV virus from mother to child placenta , parturition , no particular breastfeeding. A further object of the work is to identify the epidemiological situation in Czech Republic with respect to the vertical transmission of HIV infection , clarify the preventive actions applied to clinical practice reality on the Czech territory and optionally disclose their success . I hope the following will fill the lines sketched Metz and highlight on that page so appreciable and bulky issues , such HIV / AIDS .
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Diffraction on Spatial and/or Deep Objects
Hrabec, Aleš ; Petráček, Jiří (referee) ; Kotačka, Libor (advisor)
This discourse deals with a theoretical study of the radiation passage through a diffraction screen with non-zero size in the propagation direction of the radiation, i.e. the radiation passage through a three-dimensional object. Without any loss of generality, we solve the problem for cylindrical cavity in metal. The task exceeds evidently standard scalar theory of diffraction, thus we solve the problem using a waveguiding theory. Following the principles of the electromagnetic theory, we derive required formulae to determine mode distribution at the entry of the cavity. Further, we solve numerically the radiation propagation through the cavity, then we actually seek for radiation distribution at the very end of the cavity. This yields, with a help of the discrete Fourier transform, an intensity distribution of Fraunhofer diffraction pattern, consequently compared with an intesity distribution of the radiation pattern of Fraunhofer diffraction on infinitely thin circular opening having the radius of the cylinder cavity under study. A comparison of such patterns results to a conclusion, that the cavity length has a significatn influence on the diffraction pattern and more importantly, that the scalar diffraction theory appears incorrect for a coherent light passage through cavities longer than their radius squared. Similarly, the same conclusion is inversely proportional to a wavelength of the interacting radiation. Finally, we mention an existence of the so called "focal regime", when the radiation repeatedly exhibits roughly one order increased intensity on the symmetry axis of the cavity.
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Estrogen receptor beta (ERβ) in testicular cells and sperm
Dostálová, Pavla ; Žatecká, Eva ; Děd, Lukáš ; Dorosh, Andriy ; Postlerová, Pavla ; Jonáková, Věra ; Dvořáková-Hortová, Kateřina ; Pěknicová, Jana
Estrogen is a steroid hormone that plays an important role during sperm development in the male and female reproductive tract. Estrogen signalling is a complex process that depends on cell milieu and presence of receptors. Thanks to the steroid nature of estrogens, they can pass through the plasmatic membrane and bind to the intracellular estrogen receptors (ERs). Within the cell, there are several pools of ERs. One of them is localized to the cell nucleus and their activation leads to direct or indirect binding to DNA and ultimately to alternation in gene expression (genomic pathway). Other pools of ERs are associated with plasma membrane or are located in cytosol. Activation of membrane associated ERs leads to rapid non-genomic responses. Nowadays, two classical estrogen receptors are known – ERα and ERβ. Since ERβ is a predominant variant in testes, we focused our study on expression of ERβ variants in murine testes and sperm. We detected two variants of ERβ at mRNA level in both, testes and sperm. These variants differ in 54 nucleotids within the ligand binding domain and this variability results in different affinity to estrogen. We analyzed individual testicular cell types (spermatogonia, spermatocytes, spermatids, Sertoli cells) by RT-qPCR. Our results suggest that both ERβ variants are coexpressed in the same cell type and may therefore interact together. This may have consequences in mediating of estrogen signalling. Moreover, ERβ is expressed more in the later stages of spermatogenesis suggesting the role of ERβ in these stages or alternatively in spermatozoa alone. At the protein level, we detected ERβ in nuclear, membrane and cytosolic fraction prepared from testicular tissue suggesting the involvement of both, genomic and non-genomic, pathways of estrogen signaling in testes. In sperm, anti-ERβ antibodies localized ERβ in acrosome region and tail which is in accordance with the known role of estrogen on capacitation, acrosome reaction and motility.
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Bifurcation phenomena in vocal fold vibrations - experiments in vitro
Horáček, Jaromír ; Švec, J. ; Veselý, Jan
The study presents experimental investigations focused on monitoring of the non-linear vibration effects, especially bifurcation phenomena in the vibration of human vocal folds. The experiments were performed with excised human larynges excited by airflow. Sudden changes between different regimes of the vocal fold vibration were observed when smoothly changing the tension of the vocal folds. The study reveals further details on the nature of sudden changes between voice registers. The results also point out the possible relationship between regular (physiologic) and irregular (pathologic) vocal fold oscillations.
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Monetary Policy and Macroprudential Policy: Rivals or Teammates?
Malovaná, Simona ; Frait, Jan
This paper sheds some light on situations in which monetary and macroprudential policies may interact (and potentially get into conflict) and contributes to the discussion about the coordination of those policies. Using data for the Czech Republic and five euro area countries we show that monetary tightening has a negative impact on the credit-to-GDP ratio and the non-risk-weighted bank capital ratio (i.e. a positive impact on bank leverage), while these effects have strengthened considerably since mid-2011. This supports the view that accommodative monetary policy contributes to a build-up of financial vulnerabilities, i.e. it boosts the credit cycle. On the other hand, the effect of the higher bank capital ratio is associated with some degree of uncertainty. For these and other reasons, coordination of the two policies is necessary to avoid an undesirable policy mix preventing effective achievement of the main objectives in the two policy areas.
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Experiences of health workers with acupressure
ROUBÍČKOVÁ, Radka
The abstract of the diploma thesis is focused on the acupressure and its influence of backache of medical staff. We chose the theme of acupressure because it is a non-invasive treatment method which can be practiced by everyone in the comfort of the home and no aid is necessary to have, just the basic knowledge and training how to perform acupressure. Acupressure is not physically or time consuming and that is why it is considered as a suitable means as an additional treatment of pain and other health disorders. It can improve nursing care. The theoretical part deals with pain and pain of medical staff who are the highest risk group of backache in the lumbar region. The backache is the most frequent cause of incapacity for work. Furthermore, in the theoretical part we deal with acupressure, one of the methods of alternative medicine. For the processing of the theoretical part, we used the available foreign and Czech literary sources. The empirical part of the diploma thesis is a quantitative method. The results obtained from the research were processed in the overview tables and case reports. For the thesis we set two research objectives. The first objective was to find out the experience of medical staff with acupressure. The second objective was to verify the influence of the techniques of acupressure for backache of medical staff. On the basis of the aim two hypotheses were created. The first hypothesis should show whether the backache will be softened by application of the acupressure techniques. The second one shows whether there is the difference in approach of nurses and doctors to perform acupressure.
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Business plan
Urychová, Veronika ; Krause, Josef (advisor) ; Čámská, Dagmar (referee)
The goal of this bachelor's thesis is to create a business plan for an internet site Snouti.es, to assess its practicability and to get the strategic goals of organization straight. Snouti.es is a project of a non-profit organization which will be found for the purpose of help for animals. The thesis is divided into two main parts -- theoretical one and practical one. A business plan and its individual parts are defined in the theoretical part. Also there are written the possibilities of financing of classic organization and non-profit organization. The practical part applies the methods and theoretical knowledge in the particular business plan.
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Oxygen therapy after cardiothoracic surgery from the point of view of nurses and patients
VRCHOTOVÁ, Klára
Cardiac surgeries are very serious surgical procedures with considerable specific features. This bachelor thesis focuses on oxygen therapy from the viewpoints of nurses and patients. Its theoretical part describes physiology of breathing and the oxygen therapy as such. It describes individual sources of oxygen and indications for oxygen administration. It also describes principles to be observed during oxygen administration. Specific aids are used for oxygen administration, particularly oxygen masks or oxygen goggles. Quality pulmonary rehabilitation is also necessary to make oxygen therapy more effective. Pulmonary rehabilitation is particularly important for patients after a cardiac surgery and it should be practiced even before the surgery. This approach is critical because in the post-surgery period the therapy makes it possible for the patient to breathe and to expectorate properly. Pulmonary rehabilitation is practiced with patients by general nurses at the cardio surgery ward, as well as by physiotherapists. There are various techniques available to determine efficiency of oxygen therapy and pulmonary rehabilitation. The techniques may be classified as invasive and non-invasive; the most frequently used non-invasive method is pulse oxymetry and the most frequently used invasive technique is blood collection for ABR. Two objectives were set for the thesis. The first objective was to map knowledge of nurses about how to provide care to patients treated with oxygen therapy. The second objective was to determine how the patients feel after a cardiac surgery. Two hypotheses and two research questions were formulated. The first hypotheses were: Nurses working at the resuscitation care station have more knowledge about oxygen therapy than nurses working at the intermediate care station. The second hypothesis was: Nurses working at the resuscitation care station have more knowledge about pulmonary rehabilitation than nurses working at the intermediate care station. The first research question was: How do the patients feel during oxygen therapy and pulmonary rehabilitation? The second research question was: How are the patients after a cardiac surgery informed about oxygen therapy and pulmonary rehabilitation? In the research part of the bachelor thesis I have used both quantitative and qualitative research methods. Quantitative processing of data was used for questionnaires filled out by nurses working in the hospitals Nemocnice České Budějovice a.s., Nemocnice na Homolce in Prague and in the faculty hospital Královské Vinohrady in Prague. The method was used for evaluation and assessment of knowledge of nurses working at the resuscitation and intermediate care wards. Quantitative methods were used for processing of data obtained through semi-structured interviews with patients after a cardiac surgery. The data were transcribed and coded using a pencil and paper method. The data were categorized based on the identified codes. Two categories were created: oxygen therapy and pulmonary rehabilitation. Each of the categories was further divided into three sub-categories. Two categories were created for the research oxygen therapy and pulmonary therapy. Three sub-categories were subsequently created for the oxygen therapy and the pulmonary therapy. The quantitative research has shown that the knowledge of nurses about oxygen therapy is higher among the nurses working at the resuscitation care ward. However, the situation is different in case of their knowledge about pulmonary rehabilitation. In this case the knowledge of nurses working at the intermediate care ward was higher. The processed data from the qualitative research have shown that patients do have sufficient information about post-surgery oxygen therapy, as well as about pulmonary rehabilitation. For all patients in the post-surgery period after a cardiac surgery the frequency of pulmonary rehabilitation was higher than 1 per day.
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Nursing procedures in taking blood pressure
SEDLÁKOVÁ, Tereza
By blood pressure is meant lateral pressure or the side pressure of a blood column on the side of a vessel. The pressure is created thanks to the action of heart as a blood pump. This pressure is not the same in different parts of the bloodstream. By the blood pressure is meant the arterial pressure or pressure in the artery, so the pressure in big blood vessels. The highest values are reached in the expulsion phase of the heart action, which is called systole. The lowest values are reached in the phase of filling heart chambers, which is called diastole. The sole nursing procedures required in the process of taking a blood pressure reading are many and all must be followed. This thesis is composed of a theoretical part and practical part. Introduction to the theoretical part is composed of the main terminology from the physiology of blood pressure. In the theoretical part we follow with division on hypotension and hypertension, which are the most common diseases related to blood pressure, with diagnosis and recommendation for treatment. This thesis also offers information about measuring blood pressure by the invasive and the non-invasive method. The theoretical part is focused on the importance of the nurse in the process of measuring blood pressure with emphasis on her knowledge and practical skills.
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Coping strategies in children´s fear and pain in relation to nursing care
PROCHÁZKOVÁ, Zuzana
For the nurse, taking care of hospitalized children is important not only pediatric nursing knowledge, personal and social preconditions, but also the theoretical and practical competency of methods and techniques, which are used for identification and effective influencing of pain and fear. The aim of this thesis was to identify the main sources of fear of the hospitalized preschool and young school age children and to find out the effective methods and principles of the cooperation with children, alternatively with their accompanying parents in order to moderate the fear of the small patient. Then the thesis tried to chart the nursing diagnostic and evaluation procedure of the pain and get the most used nursing methods of non-pharmacological pain relief. To obtain the necessary data, the qualitative research was used with a semi-structured interview as a research instrument. The first research group consisted of 12 nurses, the second group consisted of 12 children ´s patients of preschool and young school age. The majority of the asked nurses thinks, that children´s patients are afraid especially of non-familiar environment, then of the awaited pain and of the solitude without parents. However, the most patients said, that they were afraid especially of pain, then of non-familiar environment, restriction of their needs, hostile attitude of the medical staff and of the other neighbouring patients. They were also frightened of the death and of the darkness. Most reported nurses mean, that the most effective solution of the children ´s fear is the friendly attitude of the medics. They also mentioned the fact of taking the focus off the fear and the presence of the parents is also beneficial. The nurses ´ answers were in conformity with patients opinion in two fields - friendly attitude of the medics and taking the focus off the fear. Then the children mentioned abiding of their specifics in connection to falling asleep and the demand of beying treated by the same sister or by few same sisters. All respondents also talked about the benefit of parents presence. Regarding the principles of the cooperation, nurses answered the importance of united medical procedures, especially the proper way of information transfer. Then the respondents nurses mentioned the psychical and emotional support for children and their accompaniments, the atmosphere of confidence and the value of well done education. Also the need of calm, silence and privacy was stated. Unlike nurses, children and their parents regarding to principles of the cooperation prefer the psychical and emotional support, then the importance of enough information was mentioned. The fourth research question bears on the methods used for children pain monitoring. The nurses said, that the intentional interview with the patients or with the parents was used as a main technique, that was stated by patients as well. Research question number five said: What are the most used nursing methods of non-pharmacological pain relief at children? Most responded nurses mentioned the distraction of children attention from the painful incentive, then the importance of physical methods, relief position and purposeful preparation for the unpleasant intervention. Nurses also named the helpful contribution of the parents, relaxing exercises and the method of imagination. Regarding the pain treatment, it was noted, that all patients prefered the analgesic therapy. Then they quoted the distraction of their attention from the painful incentive, the friendly attitude of the medics, using the ice compress and the relief position. In the pain acute phase, children required mostly calm, comfort and privacy. All children also considered the presence of parents as very helpful. The theoretical and empirical part of the thesis are suitable for being studied by nurses taking care of children and it can be helpful for nursing quality improvement at children ´s wards in hospitals.
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