|
Neuroactive steroids in human physiology and pathophysiology
Kubátová, Jana ; Hill, Martin (advisor) ; Fanta, Michal (referee)
The present diploma thesis is focused on the evaluation of steroid metabolome in body fluids in human pregnancy and parturition and also concentrates on the estimation of steroids in men with epilepsy (MWE) regarding the influence of epilepsy and its treatment with antiepileptic drugs (AEDs). The results obtained eventuate to the following conclusions: 1. They support the proposition about the key importance of corticoliberin for the timing of human parturition via stimulation of the steroidogenesis in the fetal zone of the fetal adrenal (FZ). Changes in steroid levels, however, much better predict the timing of parturition than the variation in corticoliberin. 2. The distribution of isoforms of placental oxidoreductases determines the excess of oxidized forms of the sex steroids and NAS in the fetus and the excess of their reduced forms in mother. This mechanism fundamentally affects the steroid bioactivity. The results indicate the role of NAS in pregnancy sustaining, their analgesic effect around parturition and their role in the pathophysiology of postpartum blues.
|
|
Nursing care of child with juvenilie idiopathic arthritis
Holzäpfelová, Bohumila ; Zvoníčková, Marie (advisor) ; Přibíková, Marie (referee)
Juvenilní idiopatická artritida (dále JIA) je chronické onemocnění charakterizované zánětem kloubů. Termín idiopatická vyjadřuje skutečnost, že příčiny onemocnění nejsou dosud plně objasněny. Dětská revmatologie je vedle např. dětské diabetologie či alergologie stále ještě v pozadí obecného povědomí, přestože incidence JIA juvenilního diabetu je téměř srovnatelná. Rovněž ovlivnění života nemocných dětí je zásadní a dlouhodobé. V teoretické části své práce nejprve přibližuji širší souvislosti onemocnění v kapitolách o anatomii a fyziologii kloubu, mapuji i historii revmatologie jako oboru. Problematika diagnostiky a charakteristických rysů jednotlivých forem JIA je obsahem dalších kapitol teoretické části. Pro ucelený přehled předkládám výčet současných terapeutických možností a prognostické výhledy nemocných dětí. Ošetřovatelská část je otevřena kapitolou o obecném významu ošetřovatelského procesu jako celku, blíže je charakterizován ošetřovatelský model Marjory Gordonové, podle kterého jsem analyzovala potřeby své nemocné. Napříč ošetřovatelskými diagnózami zohledňuji především velmi citlivá psychologická specifika daného věku. Práci uzavírám edukační kapitolou, ve které je možné nalézt odpovědi na otázky, které přináší denní soužití s JIA. Teoretickou i ošetřovatelskou část doplňuji přílohami a seznamem...
|
|
The status of persons with disability in the labor market in the Czech Republic
Moravcová, Magdaléna ; Čabanová, Bohumila (advisor) ; Tomášková, Vladimíra (referee)
This thesis on "The status of persons with disabilities in the labor market in the Czech Republic" deals with unemployment of people with disabilities. It explores the evolution of the social approach to persons with disabilities, that in the course of history changed attitudes of rejection in tolerant attitude. Today, the status of a group of people with disabilities is affected by broader social aspects, which include social consciousness and a focus of national policies. The status of these groups of people are also shaped by other influences, including lack of education, the existence of barriers, ignorance of employers and low motivation. Employment has many meanings to humans in the form of financial security, social contact or as the creator of the daily regime. It is important to ensure that vulnerable groups in the labor market have the same opportunities as non-handicapped. In the Czech Republic there are measures that serve to promote the employment of vulnerable groups, which include a group of people with physicall disabilities. These measures include vocational rehabilitation, advice, retraining and sheltered employment. Non-profit organizations provide employment services to unemployed persons with disabilities. An important role is also played by recommendations from the European Union....
|
|
Mythical paradigms of the avant-garde and its time
Micić, Tatjana ; Glanc, Tomáš (advisor) ; Procházka, Martin (referee) ; Jedličková, Alice (referee)
This paper is trying to present how changes of mythology, in Losev's sense, influenced art, literature and attitude towards poetic language. The study presents the Avant-garde movements in all theirs heterogenic forms, as the art of the period of crises, which appears in European culture and brought big changes in the consciousness of people. By describing an artistic attitude towards space and time we give examples how this new consciousness dealt with the spatial and time relations. Also this paper deals with the universal myths that are shown on the examples of the Avant-garde works of art. The chosen myths should present a desire of the Avant-garde movements to rebuilt, reconstruct and understand the very essence of the language of art and poetry. The Avant-garde art and literature cannot be understood if separated from the time when they appeared. Nevertheless, these movements carry in essence something that is generally characteristic of mythical thinking as well - that is, the periodical, instinctive return to essence and original purity with an aspiration to reconstruct the genetic moment and the act of creating. This phenomenon we analyze through myths that are omnipresent in European and other cultures and which appear in Avant-garde works as well.
|
|
Transit Programme in Agencies of Supported Employment for People with Mental Disabilities
Fialová, Klára ; Čedík, Miloslav (advisor) ; Zelinková, Olga (referee)
The Diploma thesis "Transition programme in agencies of supported employment for people with mental disabilities" explores the topic of the employment of people with mental disabilities in the open labour market. The theoretical section of this paper aims to clarify the concept of supported employment and to describe its process. On top of that, it deals with the issue of mental disability, in terms of classification, etiology and developmental psychology of the target group of the transition programme. This section also focuses on how the transition programme works, including such matters as education of people with disabilities, as an integral part of preparation for their future occupation. The research section examines how the successful completion of the transition programme impacts the clients, in particular their subsequent work-life, relation with the Agency and additional changes in their lifestyle. The research method was a semi-structured interview with people with mental disabilities and with workers of the agency of supported employment.
|
|
Pavlik Morozov and his role in the communist education of soviet youth
Slámová, Petra ; Ulbrechtová, Helena (referee) ; Rubáš, Stanislav (advisor)
Tématem mé bakalářské práce je ,,Pavlík Morozov a jeho role v komunistické výchově sovětské mládeže". Jejím cílem je analýza mýtu postavy Pavlíka Morozova, která v sovětském období sloužila jako vzor pro výchovu "nového sovětského člověka", v konfrontaci se skutečností. V druhé kapitole, nazvané Pavlík jako vzor sovětských dětí, se budu věnovat významu a vnímání Pavlíka Morozova, který udal svého vlastního otce. Tímto činem dokázal, že si cení více zájmů státu\ než své vlastní rodiny. Díky svému hrdinskému činu se stal vzorem několika generací sovětských dětí. Třetí kapitola objasňuje důvody a popisuje způsoby tvorby mýtu o Pavlíkovi. Sovětská vláda ponechala pouze kostru jeho skutečného životního příběhu, zbytek si dotvořila podle svých potřeb. Je zde uvedeno několik příkladů prostředků, jimiž se snažila socialistická propaganda dostat do podvědomí dětí ( vzor chování, který měly následovat. Ve čtvrté kapitole jsou uvedeny tři odlišné verze Pavlíkova příběhu. Verze spisovatele Jurije Družnikova podrobně rozebírá jednotlivá fakta uváděná v oficiální verzi a na základě důkazů dokládá jejich smyšlenost či popírá jejich pravdivost. Pátá kapitola se zabývá fenoménem udavačství, kterého se stal Pavlík Morozov symbolem. Udávání se stalo každodenním jevem, při kterém docházelo až k absurdním situacím. ~...
|
|
Comparison of non-commercial CASE tools for UML modelling
Janoušková, Irena ; Pavlíčková, Jarmila (advisor) ; Buchalcevová, Alena (referee)
Subject of this bachelor thesis is comparison of non-commercial tools for UML modeling. The opening chapter is followed by brief description of the UML language in the second chapter. The fundamental mechanisms of the language and mainly the description of all the diagrams we are able to create by the help of UML are introduced here. Software development metodologies and their importance in the modeling process are also mentioned. Third chapter focuses on characteristics and classification of all CASE tools. General description of CASE tools is followed by the list of the best known UML modeling tools, both commercial and non-commercial. A description of four selected commercial products and their features is also added for illustration. Further in this chapter, you can find a list of several non-commercial applications for UML modeling. Seven of them are chosen for evaluation and comparison. Fourth chapter focuses on the multicriteria evaluation of alternatives and presents the methods used in this thesis. In this chapter we can also find the description of chosen criteria and subcriteria and determination of their weights. The fifth chapter aims at evaluation of the selected tools according to the chosen criteria. Calculated criteria values and overall evaluation according to the chosen multicriteria evaluation of alternatives method is presented in the sixth chapter. Results are listed in lucid table format. Tools are ordered by both the overall result and results of particular criteria, so that the reader can perceive the advantages and disadvantages of the evaluated products. In the epilogue I ruminate over the results and their explanatory value.
|
|
Role and importance of traditions in the way of life
Ettlerová, Magdalena ; Šubrt, Jiří (referee) ; Duffková, Jana (advisor)
This thesis deals with the importance and role of tradition in the contemporary way of life. The term tradition represents ideas, physical objects and conduct patterns which are repeated, bringing values connected with the past, collective in observing and transmitting, including an aspect of the control executed by the authority. My thesis presents a widen postulate of the present decreasing importance of the tradition influenced by the Enlightenment. The text refers to the still continuing and newly rising traditions. The tradition maintains its position because 75 of its important functions on forming someone's identity, on the world understanding and on the individual position in the society. Without any doubt, the position of the tradition has changed a lot as compared to the traditional society. People are now less influenced by traditional authorities defending theirs own independence. They follow a tradition when it is profitable and attractive for them. They often try to avoid the unwanted duties and engagements. Individuals have now more opportunities to meet different ways of life, other traditions and customs. Today's man is more aware of ununiversality of his own tradition and is taking his way of life more reflexively. The human society should avoid the extreme situations - i.e. intolerance...
|
|
Quality of life patient with total hip replacement
Pavlišová, Marcela ; Hodačová, Lenka (advisor) ; Filková, Zuzana (referee) ; Herdová, Stanislava (referee)
Bachelors thesis is directed at perceived quality of life patients after total hip replacement. It contains theoretical and research parts. Theoretical part is consist of two parts: first part is about characterization of total hip replacement, second is about quality of life and their meaning at National Health Service. Research part is concern of questionnaires research. It passed of one hundred patients at Medical spa Bohdaneč. It compared quality of life before and after operation.
|
|
The Litvinenko case and its reflection in The Daily Telegraph
Prošková, Alexandra ; Slanec, Jaroslav (referee) ; Němcová Tejkalová, Alice (advisor)
This bachelor thesis studies the manner in which the case of the former Russian spy Alexander Litviněnko's poisoning was handled in 2006 by the British newspaper The Daily Telegraph. Both quantitative and qualitative analyses have been used for that purpose. The theoretical part of the thesis explains the factors influencing the process of encoding of the meanings into mediated contents, and the process of their subsequent decoding by the public. The analytical part presents a detailed description of how the concrete news texts on the Litvinenko case published by The Daily Telegraph could have been perceived by their recipient. Hypotheses have been set for the analysis; the confirmation or denial of their validity outlines The Daily Telegraph's methods of news reporting production and the terms in which the news texts are conceived in this newspaper.
|
guest ::
