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The Analysis of Motivation and Satisfaction of the Clients of NZDM in Třebíč
HONSOVÁ, Ivana
This thesis specifies the term NZDM - specific social care service for children and youth, and characterizes the following terms: motivation, satisfaction and NZDM client. It goes on to describe one of these centres located in the town of Třebíč in which the research took place. The aim of this research was to assess the situation in the area of motivation and satisfaction of clients of such establishments. In addition, it aimed to identify the reasons why clients visit such establishments and whether they are satisfied with the services or would welcome some changes. To collect the data the researcher used one of the methods of qualitative research, concretely the fully structured interview. The gained results were summarized in the discussion and conclusion of the thesis.
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Institutions for Leisure Time Spending of the Youth up to the age 18
Hyršlová, Iveta ; Polišenský, Miroslav (advisor) ; Gabriela, Gabriela (referee)
The diploma thesis deals with the institutions for leisure time in the capital city of the Czech republic. This is a House of children and youth, whose founded by the capital city of Prague.The thesis is divided into two parts, theoretical and part of the research. In the first part of the thesis is defined by the concept, development and function of leisure time and different views on leisure time. Is indicated here, what does the pedagogy of leisure time mean. A large section is devoted to institutions and institutions for leisure time. Defined forms of institutions for leisure time activities and their functioning. In the theoretical part is explained what is meant by universal institutional structure, which is an important basis for institutional analysis in the research section. The research part of the thesis deals with the characteristics all the information about the House Children and Youth in Prague 7. The most important part of the research is the analysis of the institutional follow-up to the House of children and youth. The aim is to assess whether and the extent to which the institution carries out its percent of the mission. In the final discussion summarizes the recommendations that could lead to improve the operation of the institution.
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HIV - 1 Protease: Insights into Drug Resistance Development
Grantz Šašková, Klára ; Konvalinka, Jan (advisor) ; Forstová, Jitka (referee) ; Dohnálek, Jan (referee) ; Schiffer, Celia (referee)
Amino acid changes within HIV protease or its substrate that decrease the susceptibility to protease inhibitors represent a highly complex issue still not yet fully understood. Various mechanisms by which this often complicated pattern of mutations influence drug binding needs to be analyzed on a molecular level by a series of methods including experiments with recombinant viruses, biochemical enzyme analysis, structural and thermodynamical studies or molecular dynamics. Each result may help to complete the overall picture of protease inhibitor resistance evolution and therefore contribute to the design of more powerful 3rd generation HIV/AIDS drugs. This thesis presents several analyses of HIV resistance development on molecular level. We have focused on the nelfinavir resistance pathway, lopinavir mutation score, emergence of amino acid insertions in HIV protease gene and their contribution to protease inhibitor resistance and finally we analyzed a highly mutated protease species isolated from patients failing darunavir therapy. Since we are able to accomplish a wide combination of techniques, we could explain and put together some pieces of viral evolution considering the final steps of HIV life cycle and also provide knowledge necessary for novel inhibitor design. Aims of the Project There were...
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Services for children and adolescent in region of Prague 13
Moravcová, Běla ; Pazlarová, Hana (advisor) ; Kodymová, Pavla (referee)
In its theoretical part the Bachelor Thesis "Services for children and youth in the area of Prague 13" speaks about social services, their acreditation and standarts of quality in social services. Short chapter is dedicated to community planning which has become the most widely spread form of both social services and of services in general. Further on in the thesis types of services for children and youth are mentioned according to how they are defined by law and specialised literature. This part concerns the services that can be used by children and youth mostly during their leisure time. Practical part is centered on the area of Prague 13 which is fastly growing area that where the new inhabitants are accepted. Later in the work is a remark about the sociodemographic structure about this district of Prague. There are discussed separate areas of the life in Prague 13 and the coverage of this area by the services for children and youth and about how they are perceived by average user. According to the law n.108/2007 of the code about the social services, services are communaly planned there too. There was also made a research about the needs of the users of social services. In expert reasearch which covers 12 respondents belonging to the providers of the services there are covered their views of the...
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International security with the focus on Islamic region. Searching the premises of the Hizbullah martyrdom on a multilevel analysis
Kočišíková, Viera ; Lehmannová, Zuzana (advisor) ; Eichler, Jan (referee) ; Gombár, Eduard (referee) ; Danics, Štefan (referee)
Most of the existing researches on martyrdom are based on single factor analysis and ignore the fact that this phenomenon is a result of individual psychology and the influence of the environment. That is why most of the researchers aim for multi level approach of the analysis. Only few of them though worked out this approach into a formal model. Although most of the researchers agree that the three level analysis approach is neccessary, most of the researches are based on two level analysis approach. Three level analysis approach was first introduced by Kenneth Waltz (1988) in his research on the causes of war more than fifty years ago. In Waltz model the most fundamental parts neccessary to understand internatinal affairs are individual, state and the state environment. If this is transformed into the matter of terrorist groups we get a three level model of Assaf Moghadam which is based on Waltz's model. In Moghadam's model a state is replaced by a relevant organization and the last level of Waltz's model is replaced by the structural level. Presented thesis is based on the research of Assaf Moghadam and his three level analysis model of suicide terrorism. The main objective of the thesis is the application of Moghadam's model to the martyrdom operations of Hizbullah. Based on this analysis the conditions leading to martyrdom operations of Hizbullah are being searched as well as the level of racionality of these operations is being questioned. The individual level of analysis focuses on the motivation of individuals, the members of Hizbullah who decided to participate in martyrdom operations, deals with the role and impact of charismatic leader and tries to analyse the correlation of poverty and lack of education and martyrdom. It also examines the motivation of individuals and based on the biographic data tries to create a profile of Hizbullah martyr. The organizational/collective level explains the motivation of the organization, Hizbullah, to use martyrdom. The structure and goals of the organization as well as its regional relations and how this context might influence the use of martyrdom are being examined. It deals as well with the forms of indoctrination Hizbullah uses to attract members as well as voters. The transformation of Hizbullah from the radical zealots into a political group, member of government is being portrayed. The structural level analyses external factors derived from the environment that might play role in developing the martyrdom within Hizbullah. The thesis focuses on selected factors such as shi'ite cult of martyrdom, history of shi'a islam connected with oppression, regional history and main historical milestones etc. It shows the examples of martyrdom within the history among both religious and secular groups. Individual and organizational level are closer connected to the martyrdom operation itself than the structural level. Some of the main structural factores are being examined directly on indivual and organizational level. Those important factors are shi'te religion and the cult of martyrdom, conflict with Israel- the occupation of Southern Lebanon, role and impact of other regional powers.
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Synthesis of tetrapyridoporphyrazines with potential photodynamic activity
Vavrečková, Magda ; Zimčík, Petr (advisor) ; Kučerová, Marta (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department Department of Pharmaceutical Chemistry and Drug Control Candidate Magda Vavrečková Supervisor Doc. PharmDr. Petr Zimčík, Ph.D. Title of Thesis Synthesis of tetrapyridoporphyrazines with potential photodynamic activity Substituted tetrapyridoporphyrazines represent new structural type of potential photosensitizers with interesting properties for application in photodynamic therapy. The aim of this work was to synthesize two types of tetrapyridoporphyrazines with hydrophilic substituents as potential photosensitizers. Photosensitizers are substances with an ability to produce singlet oxygen after activation by light. Singlet oxygen is the key toxic species in photodynamic therapy. 2-Chloro-5,6-dimethylpyridine-3,4-dicarbonitrile (1) was prepared in the first step by condensation of tetracyanoethylene and butan-2-one. In the next step, a hydrophilic substituent was attached by nucleophilic substitution. The first precursor was prepared by reaction of compound 1 with 2-mercaptoethanol in the presence of sodium hydroxide. Similarly, the second precursor was obtained by reaction of compound 1 with diethylaminoethanol in the presence of sodium hydride. The third step involved cyclotetramerization with magnesium butoxide as...
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Automatizace testování architektury studentských úloh
Hamendi, Mohammed ; Pecinovský, Rudolf (advisor) ; Pavlíčková, Jarmila (referee)
The freshmen programming courses at the University of Economics in Prague offer a unique approach to learning the art of programming and software engineering. The introductory courses follow the Architecture First methodology that gives students the opportunity to learn programming from the top down, without being constrained by the specifics and syntax of any one programming language. It teaches the thought processes needed to build programs, allowing the student to absorb the big ideas of computer programming. The average number of freshmen at the faculty of Informatics and Statistics is around seven hundred students. The task of correcting programming assignment and preparing appropriate feedback would be a mammoth undertaking for teaching staff in most university settings worldwide that offer similar computing degrees. It is therefore quite often the case that the faculty provisions some sort of automated testing technology that can handle the volume and provide both the teaching staff and the students with the tools needed to manage the assignments. These automated tools or systems have been, and continue to be, the subject of many research topics across the world and continue to evolve as new technologies and teaching methods evolve. This study first introduces the theoretical background of automated assessment and grading tools and systems and then provides an analysis of the fields current state. Taking that as input to the next phase, the study uses that information to then design and implement a custom-built system that would enable the automated testing of the structure and other aspects of student assignments. The main goal for the resulting system is to provide an intuitive and convenient way of declaring what needs to be tested for a given assignment and then providing the mechanism to run those tests automatically. The resulting system, DynoGrader, dynamically validates student assignments at runtime using Java runtime annotation processing mechanisms and Java Reflection API.
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Tax and social security systems in selected EU countries
Vágnerová, Pavlína ; Tepperová, Jana (advisor) ; Čejková, Eliška (referee)
The aim of this master thesis is the comparison of selected elements of the tax and social security systems in the Czech Republic, Slovakia, Austria and Germany, which are related to employees and employers and it is counted with them in model examples, then evaluation of advantages and disadvantages of employees´ migration under the structure of posting between the Czech Republic and other countries and finally the comparison of employees´ incomes after receiving benefits from social security system of each country (especially old age pension and parental allowance). In the first part of the thesis there is explained problematics of double tax treaties and EU coordination of social security. Then there is the comparison of above mentioned elements of the tax and social security systems in each country. In the last part I apply findings on model employees and I make a conclusion from amount of their net incomes. Migration to another EU member country is the most profitable for employee who is subjected to taxation in other EU countries but he remains under the Czech social security system. In terms of social benefits, retired people are supported the most in Austria and families with children in Germany.
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POSSIBILITY OF TERRITORIAL AND LOCAL DEVELOPMENT AT THE AREA OF STARÉ HOBZÍ VILLAGE
VOLDŘICHOVÁ, Zuzana
The thesis is looking into development of Staré Hobzí village, which is consisted of five country residences (Staré Hobzí, Nové Hobzí, Vnorovice, Nové Dvory, Janov), specifically into drawing up a proposal of Village Renewal Programme. The introduction includes brief characteristic of the village environment in relation to territorial and local development, as well as analysis of the village literature and development materials. In the next part it gathers suggestions for the next development of the country residences, which were gained from the development materials, conversation with local experts, as well as from asking local inhabitants (extensive survey) and from personal terrain research of the residences and surrounding territory. The thesis proceeds to a proposal of structured system of activities of the Staré Hobzí Village Renewal Programme, which includes activities that support cultural and sports life, entrepreneurship, maintenance and reconstruction of buildings and public areas, completion of the technical infrastructure, and supporting the village cooperation with other villages.
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