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Clock genes in mammalian circadian pacemaker
Cimerová, Veronika ; Bendová, Zdeňka (advisor) ; Polidarová, Lenka (referee)
The behavior of mammals and their physiological processes are dependent on the daily rhythms. These rhythms are controlled by an endogenous circadian clock that responds to light/dark cycles of environment. In mammals, the circadian clocks, are arranged hierarchically, and work in almost all cells and tissues. Suprachiasmatic nuclei (SCN) in the hypothalamus are at the top of the hierarchy and work as a major circadian pacemaker. This work presents the clock genes that have been discovered in the last twenty years in the SCN of mammals. The first chapter focuses on the general mechanism of circadian rhythms and structure of the SCN. The second chapter describes the transcriptional-translational feedback loops that are an essential part of the proper function of the circadian clock, and function of individual genes is briefly introduced in this chapter. The following chapters already include a chronological characterization of Clock, Bmal1, Period and Cryptochrome genes, as they were discovered. If the clock gene expresses different function from the clockwork mechanism, it is briefly introduced in the final paragraph on the chapter. The final chapters deal with other molecules, casein kinases, ROR and REV-ERB receptors that affect its function expression and degradation of circadian genes in the...
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Circadian clock genes in insects
BAZALOVÁ, Olga
This thesis focuses on molecular characterization of circadian clock genes in insects. It explores genetic diversity of circadian clock genes by molecular characterization of several insect species including two dipteran flies (Musca domestica and Drosophila melanogaster), two cockroach species representing ancestral insects, and the linden bug, Pyrrhocoris apterus. Furthermore it considers various roles of circadian clock genes in insect physiology. Application of molecular-biology methods in Pyrrhocoris apterus, non-model insect species, enable us to investigate involvement of circadian clock genes in photoperiod induced physiological responses. Application of molecular-biology methods in Periplaneta americana and Blattella germanica was used to explore involvement of circadian clock genes in magnetoreception.
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Microcontroller controlled timer
Heralecký, Lukáš ; Macháň, Ladislav (referee) ; Pavlík, Michal (advisor)
Bachelor thesis entitled "Microcontroller-controlledtimer" is focused on design and practical application created a device that will be capaje of depending on external dating of simple tasks. This paperdescribes the features and capabilities of the microcontroller ATmega162, the Operations and program services. There is also described several other components used such as RTC, LCD display, matrix keyboard, temperature and othersensors. The first part is devoted to the oretical introduction to microcontroller and used parts. In another part ofthe PCB design - suitable layout of components, connectors, location, solving problems in PCB design. Fortesting functions designed and manufactured equipment is made simple test PCB. The practical part ended custom programming microcontroller programming language C.
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Modernization of the master clock for slave clocks controlling
Pokorný, Jiří ; Číž, Radim (referee) ; Krajsa, Ondřej (advisor)
This diploma thesis describes modernization of the master clock HN 50 created by company ELEKON, s.r.o. Master clock can be used for controlling of analog or digital slave clock or for switching school bells. Exact differences between old and new version of the clock are described and ways of synchronization and controlling of slave clock are explained. Main goal of modernization is applying the SMT technology for automation of production. Another problems and shortcomings of previous version are developed, such as new power supply structure, selection of a new microcontroller and usage of several different displays. Every problem is developed and new solutions are chosen. Last part of the document describes the software which is clarified on several flowcharts. Outputs of the thesis are complete schematics, printed circuit boards and 3D models of the modernized device.
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Advanced Alarm Clock for Windows Phone 7
Zapletal, Josef ; Kajan, Rudolf (referee) ; Herout, Adam (advisor)
This bachelor thesis describes the development of mobile application for Windows Phone 7 focused on sleep and awakening the user. The application is very easy to use and uses built-in modules of advanced mobile phones, such as high resolution camera and the accelerometer. This thesis describes the main features of Windows Phone 7 platform, analysis of competing solutions, application concept and its implementation. Furthermore, this work describes the solution of various problems in the development and also provides examples of methods and tools. Finally, there is also a list of used libraries.
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Contiki NTP Client
Luštický, Josef ; Čejka, Rudolf (referee) ; Kašpárek, Tomáš (advisor)
This BSc Thesis was performed during a study stay at the RheinMain University of Applied Sciences in Wiesbaden, Germany. The purpose of this thesis is to describe the operating system Contiki for embedded systems, NTP time synchronisation protocol and to design and implement an NTP client for the Contiki operating system.
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Design of Alarm Clock
Budík, Marek ; Rubínová, Dana (referee) ; Rajlich, Jan (advisor)
The goal of this thesis is to create an original and functional design of personal alarm clock. This design will meet high technical, ergonomic and aesthetic standarts for succesful product. Side goal is to conceive a machine with unique character.
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