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Advances in antithrombotic prophylaxis and therapy
Vykrutová, Iva ; Tilšer, Ivan (advisor) ; Melicharová, Ludmila (referee)
Thrombotic disease and it's consequences are worlwide one of the leading causes of death. There are prescribed anticoagulants for treatment and prevention. Currently these prescribed drugs - cumarins, unfractioned and fractioned heparins, which have many adverse effects are tried to be replaced. This review is focused on summary informations about two new anticoagulants drug - direct inhibitor f Xa (rivaroxaban) and direct thrombin inhibitor (dabigatran), which could substitude currently used drugs in future. These new substances were clinical tested, where proved safety and efficiency. In these days their indication allow for patients after knee and hip joint replacement. Advantages of rivaroxaban and dabigatran: per os aplication once a day predictable pharmacokinetics and therapeutic response low potencial of drug interaction no needs of monitoring of coagulation Disadvantages of rivaroxaban and dabigatran: limited experience yet significant financial cost unknow antidote In the future these drug could be used for other indications.
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Analysing company's behaviour and communication on social networks
Němec, Milan ; Molnár, Zdeněk (advisor) ; Jelínek, Ivan (referee)
This thesis focuses on measuring company´s communication and behaviour on social networks. To capture the interaction between the company and its users the thesis uses web analytics tools. Therefore, the main objective of the thesis is analysis of these tools. To achieve this goal, the thesis characterizes social networks and their marketing opportunities for business promotion. Thanks to this, needs of using these tools is identified. The needs are: competitive analysis, optimizing communication, measuring achievement of objectives or detection competitive viral content. Research questions were determined and then analysis tools found answers to research questions. It was found that the tools provide various views of data and create a complete system for measuring and analysing behaviour and communication companies on social networks. The results were validated in a case study focused on the Facebook profile of the University of Economics in Prague. The study analysed the interaction profile of the school and its users and compared with others schools. In the results the analysis tools are validated and it is designed recommendation for improve engagement. This thesis revealed strengths and weaknesses of tools for measuring company´s communication and behaviour on social networks. It was found that these tools have wide range of use. They can be used for understanding the company's profile, its users, for purposes of competitive analysis, monitor corporate goals and optimize communications on social networks.
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Possibilities of Big Data use for Competitive Intelligence
Verníček, Marek ; Molnár, Zdeněk (advisor) ; Šperková, Lucie (referee)
The main purpose of this thesis is to investigate the use of Big Data for the methods and procedures of Competitive Intelligence. Among the goals of the work is a toolkit for small and large businesses which is supposed to support their work with the whole process of Big Data work. Another goal is to design an effective solution of processing Big Data to gain a competitive advantage in business. The theoretical part of the work processes available scientific literature in the Czech Republic and abroad as well as describes the current state of Competitive Intelligence, and Big Data as one of its possible sources. Subsequently, the work deals with the characteristics of Big Data, the differences from working with common data, the need for a thorough preparation and Big Data applicability for the methods of Competitive Intelligence. The practical part is focused on analysis of Big Data tools available in the market with regard to the whole process from data collection to the analysis report preparation and integration of the entire solution into an automated state. The outcome of this part is the Big Data software toolkit for small and large businesses based on their budget. The final part of the work is devoted to the classification of the most promising business areas, which can benefit from the use of Big Data the most in order to gain competitive advantages and proposes the most effective solution of working with Big Data. Among other benefits of this work are expansion of the range of resources for Competitive Intelligence and in-depth analysis of possibilities of Big Data usage, designed to help professionals make use of this hitherto untapped potential to improve market position, gain new customers and strengthen the existing user base.
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European funds and their usage for logistics projects in Czech Republic.
Číhalová, Denisa ; Jirsák, Petr (advisor) ; Joura, Adam (referee)
The thesis discusses the issue of freight villages and the possible usage of European funds for their construction. The topic is very actual because by the current program period 2014-2020 has appeared change concerning the financial support of multimodal freight transportation. The aim of this thesis is to determine, whether from the production companies operating in the automotive industry exists demand for such a freight villages. Needed information has been obtained on the basis of in-depths inteviews of manufacturing companies located in the region Vysočina.
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A novel nanospray liquid junction interface for versatile CE-MS
Křenková, Jana ; Haselberg, R. ; Somsen, G. W. ; Foret, František
In this work we present a new polyimide-based liquid junction nanospray interface, combining the advantages of sheath flow and sheathless designs. The liquid junction interface was prepared as a hybrid microfabricated plastic liquid junction sprayer allowing to perform analysis in standard (30-100 micro m ID) separation capillaries. The interface incorporates a self-aligning port for coupling of the separation capillary as well as ports for automated flushing of both the liquid junction and the separation capillary. The interface permits performing CE both with and without electroosmotic flow. The use of large bore capillaries allows injection and preconcentration of larger sample volumes, favoring detection sensitivity. Different compositions of the spray liquid and BGE can be used when needed.
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Czech television and it's content for Generation Y
Jůzová, Klára ; KRUML, Milan (advisor) ; Zlatušková, Kamila (referee)
This thesis focuses on the changes the television industry has undergone in recent years. The aim of the thesis is to define a specific audience group and its preferences: the current generation of young people aged between 15 and 35 who belong to the sociological group called "Generation Y". The thesis contributes to knowledge by examining how the public Czech Television (CT) understands and addresses the needs of this specific audience group.
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Dance education of preschool hyperactive children
Lacková, Ivana ; LÖSSL, Jiří (advisor) ; FRIČOVÁ, Marie (referee)
The topic of this diploma thesis is Dance education of preschool hyperactive children. Goal of research is to describe teaching of hyperactive children especially dance lessons.
There is described Attention Deficit Hyperactivity Disorder in the first part of thesis. There is written about special needs of children with ADHD focused on education.
Second part is focused on practical dance lesson of ADHD children. There is described example dance lesson based on theory and practical experience of experts.
The result of research is that supply of special lessons is very limited and it is big pity. In the diploma thesis was recognized that the education with special program should help to children with ADHD and it can be good supplement to standard medical therapy.
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Association of Idependent Theatres of the Czech Republic – Analysis and Description of the Current State
Bodoríková, Markéta ; KAŠPAR, David (advisor) ; PROKOP, Petr (referee)
The thesis is focused on newly established Association of Independent Theaters of the Czech Republic, officially using the abbreviation AND ČR. The aim of the thesis is to describe formation of the association, its current state, future plans and its functioning. The first part examines the term “independent professional theater” and briefly characterizes selected organizations from the Czech Republic and Europe with the potential to meet with the AND ČR in the cultural area in future. In the following parts were researched needs of independent professional scene in Prague and was described the needs analysis for the field of “independent” theater from the year 2013. The thesis describes the development of AND ČR, its activities up to current stage, organizational structure and future short-term plans. In the final part of the thesis, there is defined the management system of the association and established its possible improvements so the AND ČR would become the leading organization representing independent professional theaters in the Czech Republic.
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Age management
Jirásková, Barbora ; Dvořák, Marek (advisor)
This thesis processes the concept of the human resources management with respect to the age structure of employees in the intentions of the Czech Republic. In the theoretical part, there is outlined the history of the application of the principle of age management, focusing on current demographic trends, forecasts of population age structure, the aging workforce and the need to preserve the ability to work into old age. Points to the need to adapt corporate strategy, personnel management trend of an aging population. It presents ideas for the main underlying programs and legislative measures which form the basis of the latest concepts and strategic plans in the Czech Republic and Europe. The empirical part deals with a specific level of allowance organization established by TSU and two sub investigation. The first is a case study of age management staff. The resulting data are confronted with the results of a survey among employees of the organization. The second investigation are interviews with members of management and employees of the HR department on the issue of the introduction of age management, their awareness of the concept of age management, the question of age discrimination, the issue of maintaining the continuity of knowledge in the organization and their views on these topics. The outcome of this survey indicates a willingness and readiness of the organization has already received age management principles adhere to and develop further.
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Information systems of secondary education
Charvátová, Jindřiška ; Vaněk, Jiří (advisor) ; Věra, Věra (referee)
This dissertation Information system of secondary education deals with a practical application of the information system used at the Secondary Vocational school of Gastronomy and Business in Prague, which mainly aims at the presentation of an overview, exploitation and assessment of information systems for secondary schools and based on a questionnaire survey suggests a solution to the given situation.
The theoretical part of the thesis shows a summary and application of the information systems for secondary schools based on secondary research of literature and available sources. The practical part is primarily targeted at research concerning practical application of the information system. The other part refers to a needs analysis of the pedagogical staff referring to the application of the school IS in the form of a questionnaire survey. Subsequent improvement proposals are made based on the outcome evaluation.
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