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Advances in antithrombotic prophylaxis and therapy
Vykrutová, Iva ; Tilšer, Ivan (advisor) ; Melicharová, Ludmila (referee)
Thrombotic disease and it's consequences are worlwide one of the leading causes of death. There are prescribed anticoagulants for treatment and prevention. Currently these prescribed drugs - cumarins, unfractioned and fractioned heparins, which have many adverse effects are tried to be replaced. This review is focused on summary informations about two new anticoagulants drug - direct inhibitor f Xa (rivaroxaban) and direct thrombin inhibitor (dabigatran), which could substitude currently used drugs in future. These new substances were clinical tested, where proved safety and efficiency. In these days their indication allow for patients after knee and hip joint replacement. Advantages of rivaroxaban and dabigatran: per os aplication once a day predictable pharmacokinetics and therapeutic response low potencial of drug interaction no needs of monitoring of coagulation Disadvantages of rivaroxaban and dabigatran: limited experience yet significant financial cost unknow antidote In the future these drug could be used for other indications.
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Urban development of the town of Lomnice nad Popelkou
Musilová, Barbora ; Kouba, Vojtěch (advisor) ; Lindner, Milan (referee)
This thesis deals with the urban development of Lomnice nad Popelkou and conservation areas within its territory. Describes the history of the city and examines causes of the current condition of the monument fund. Describes the efforts of the city representatives in buildings restoration, through the City Development Strategy for period of 2016 - 2023. This thesis assesses the extent to which this strategic document managed to respond to the condition of historic buildings and also the needs of city residents.
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The Image of the Artist in Czech Feature Films after 1948
Šlingerová, Alena ; Klimeš, Ivan (advisor) ; Přádná, Stanislava (referee)
After the Czechoslovak coup d'état of 1948, the cultural politics of the Communist Party became the only power that should organize, regulate and evaluate cultural affairs. This brouht radical changes of the status of artists. That artists who belonged to the rank of intellectuals had to follow needs of the new kind of society. They accepted orders from above and their activity was strictly controlled. Proletarian amateurs and folk art were officially encouraged. The examples of the progressive art were found in the USSR and also among personalities from the history of the national culture. Cinematography, to which was placed a requirement of topicality, also presented the new image of the artist. The most noticeable results were reached in biografical films about our classics and films exposing folklore and cultural life of the working class. The integration of an intellectual artist into the new society became a pivotal theme in movies Písnička za groš and Nezlob, Kristino. As episodic characters, we can find also completely negative types of artists - enemies of that new society. This spectrum corresponds to a general typology of people that was used in art, journalism and public speech in general: mature, confused and totally inadaptable (designed to be displaced). Exeptional cases of...
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Analysing company's behaviour and communication on social networks
Němec, Milan ; Molnár, Zdeněk (advisor) ; Jelínek, Ivan (referee)
This thesis focuses on measuring company´s communication and behaviour on social networks. To capture the interaction between the company and its users the thesis uses web analytics tools. Therefore, the main objective of the thesis is analysis of these tools. To achieve this goal, the thesis characterizes social networks and their marketing opportunities for business promotion. Thanks to this, needs of using these tools is identified. The needs are: competitive analysis, optimizing communication, measuring achievement of objectives or detection competitive viral content. Research questions were determined and then analysis tools found answers to research questions. It was found that the tools provide various views of data and create a complete system for measuring and analysing behaviour and communication companies on social networks. The results were validated in a case study focused on the Facebook profile of the University of Economics in Prague. The study analysed the interaction profile of the school and its users and compared with others schools. In the results the analysis tools are validated and it is designed recommendation for improve engagement. This thesis revealed strengths and weaknesses of tools for measuring company´s communication and behaviour on social networks. It was found that these tools have wide range of use. They can be used for understanding the company's profile, its users, for purposes of competitive analysis, monitor corporate goals and optimize communications on social networks.
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Possibilities of Big Data use for Competitive Intelligence
Verníček, Marek ; Molnár, Zdeněk (advisor) ; Šperková, Lucie (referee)
The main purpose of this thesis is to investigate the use of Big Data for the methods and procedures of Competitive Intelligence. Among the goals of the work is a toolkit for small and large businesses which is supposed to support their work with the whole process of Big Data work. Another goal is to design an effective solution of processing Big Data to gain a competitive advantage in business. The theoretical part of the work processes available scientific literature in the Czech Republic and abroad as well as describes the current state of Competitive Intelligence, and Big Data as one of its possible sources. Subsequently, the work deals with the characteristics of Big Data, the differences from working with common data, the need for a thorough preparation and Big Data applicability for the methods of Competitive Intelligence. The practical part is focused on analysis of Big Data tools available in the market with regard to the whole process from data collection to the analysis report preparation and integration of the entire solution into an automated state. The outcome of this part is the Big Data software toolkit for small and large businesses based on their budget. The final part of the work is devoted to the classification of the most promising business areas, which can benefit from the use of Big Data the most in order to gain competitive advantages and proposes the most effective solution of working with Big Data. Among other benefits of this work are expansion of the range of resources for Competitive Intelligence and in-depth analysis of possibilities of Big Data usage, designed to help professionals make use of this hitherto untapped potential to improve market position, gain new customers and strengthen the existing user base.
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Diagnostics for Robust Regression: Linear Versus Nonlinear Model
Kalina, Jan
Robust statistical methods represent important tools for estimating parameters in linear as well as nonlinear econometric models. In contrary to the least squares, they do not suffer from vulnerability to the presence of outlying measurements in the data. Nevertheless, they need to be accompanied by diagnostic tools for verifying their assumptions. In this paper, we propose the asymptotic Goldfeld-Quandt test for the regression median. It allows to formulate a natural procedure for models with heteroscedastic disturbances, which is again based on the regression median. Further, we pay attention to nonlinear regression model. We focus on the nonlinear least weighted squares estimator, which is one of recently proposed robust estimators of parameters in a nonlinear regression. We study residuals of the estimator and use a numerical simulation to reveal that they can be severely heteroscedastic also for data generated from a model with homoscedastic disturbances. Thus, we give a warning that standard residuals of the robust nonlinear estimator may produce misleading results if used for the standard diagnostic tools
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Czech television and it's content for Generation Y
Jůzová, Klára ; KRUML, Milan (advisor) ; Zlatušková, Kamila (referee)
This thesis focuses on the changes the television industry has undergone in recent years. The aim of the thesis is to define a specific audience group and its preferences: the current generation of young people aged between 15 and 35 who belong to the sociological group called "Generation Y". The thesis contributes to knowledge by examining how the public Czech Television (CT) understands and addresses the needs of this specific audience group.
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Dance education of preschool hyperactive children
Lacková, Ivana ; LÖSSL, Jiří (advisor) ; FRIČOVÁ, Marie (referee)
The topic of this diploma thesis is Dance education of preschool hyperactive children. Goal of research is to describe teaching of hyperactive children especially dance lessons.
There is described Attention Deficit Hyperactivity Disorder in the first part of thesis. There is written about special needs of children with ADHD focused on education.
Second part is focused on practical dance lesson of ADHD children. There is described example dance lesson based on theory and practical experience of experts.
The result of research is that supply of special lessons is very limited and it is big pity. In the diploma thesis was recognized that the education with special program should help to children with ADHD and it can be good supplement to standard medical therapy.
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Association of Idependent Theatres of the Czech Republic – Analysis and Description of the Current State
Bodoríková, Markéta ; KAŠPAR, David (advisor) ; PROKOP, Petr (referee)
The thesis is focused on newly established Association of Independent Theaters of the Czech Republic, officially using the abbreviation AND ČR. The aim of the thesis is to describe formation of the association, its current state, future plans and its functioning. The first part examines the term “independent professional theater” and briefly characterizes selected organizations from the Czech Republic and Europe with the potential to meet with the AND ČR in the cultural area in future. In the following parts were researched needs of independent professional scene in Prague and was described the needs analysis for the field of “independent” theater from the year 2013. The thesis describes the development of AND ČR, its activities up to current stage, organizational structure and future short-term plans. In the final part of the thesis, there is defined the management system of the association and established its possible improvements so the AND ČR would become the leading organization representing independent professional theaters in the Czech Republic.
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The use of biographical anamnesis in care for clients with dementia in homes for the elderly in České Budějovice.
ČÁPOVÁ, Pavlína
Basic theoretical background: The number of people suffering from dementia is increasing, mainly due to falling birth rate and lengthening of life expectancy. The World Health Organization deals with the issue of caring for clients with dementia in a detailed report. A summary of this report was written by the Institute of Health Information and Statistics of the Czech Republic.In this summary, it is stated that in 2011 the number of clients treated in outpatient care in the Czech Republic climbed to number 14,932 (of which 67% were women) diagnosed with F00 (Alzheimer's disease) and with F01 - F03 (other dementia) to 17,955 (of which almost were women). In 2010, the estimated global number of patients with dementia was 35,6 million. Our society constantly considers a person with dementia to be an uncommunicative client, who is very difficult to be cared (Kopecká, 2012). That is why dementia touches not only the bio-psycho-social, but also the economic field (Wija, 2012). The basis of the psycho-biographical model of care is to change the perspective to the client and to see him or her as a personality with his or her own individual, regional or collective biographical history. With the help of the psycho-biographical model, the care becomes more tolerant, as this model is primarily focused on maintaining and supporting self-care skills and reflecting client's current skills, especially his or her mental ability (Procházková, 2011). For clients with dementia it is essential to find a way to their emotional life, which can be achieved by means of the information from the client´s biography. The knowledge of the client's story of life will also explain his or her needs and requests in care (Kopecká, 2012). The psycho-biographical model improves care for clients with dementia, particularly in the area of individual care and activation of clients. Aims of the thesis: As for the research part of this thesis, two objectives were defined. The first objective was to find out nurses' opinions about the use of biographical history in homes for seniors in České Budějovice. The second one was to discover the influence of biographical history in care for clients in homes for seniors in České Budějovice. These research questions were set to these objectives: What do nurses working in nursing homes for seniors in České Budějovice think of the influence of biographical history in care for clients? Another research question was: In what ways do the nurses working in nursing homes for seniors in České Budějovice think the biographical history improves care for clients? Methodology: The research on the topic of using biographical history in caring for clients with dementia in nursing homes for seniors in České Budějovice was conducted via qualitative investigation. Semi-structured interviews with nurses working in nursing homes for seniors in České Budějovice were chosen for the data collection. Results: The results of the research showed that all respondents found the use of biographical history beneficial in care for clients with dementia, especially in the area of improving individual care, cooperation with the client and his or her family members and obtaining information about the client. All respondents would like to start using biographical history in caring for clients with dementia, although some of them would find the introduction of the model into practice quite problematic. Conclusion: The results of this research could be used to change the approach to care for clients with dementia and to improve the quality of care. This thesis could serve to nurses in charge as a background material for the introduction to this issue and for considering the possibility of introducing biography history in caring for clients with dementia, as all interviewed respondents reported working with clients´ biographies to be beneficial in care for clients with dementia.
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