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The hip fracture register, optimalization of hip hemiarthroplasty position
Skála - Rosenbaum, Jiří ; Bartoníček, Jan (advisor) ; Chomiak, Jiří (referee) ; Janeček, Miloš (referee)
The study examines the monocentric epidemiological data of patients with hip fractures from 1997-2007. Adult patients treated for hip fracture between the years 1997-2007 were included in the study. Retrospective statistical assessment of continually gathered data focused on epidemiology and demographics. The second part of the study was concerned on risk factors on protrusion of hemiarthroplasty into the acetabulum. The goal was to specify exact indication, proper operative technique and selection of the implant. The study involved 3 683 patients (2 678 women, 1 005 men). Patients older than 70 years accounted for 82 % of all cases. There was an increase in the number of hip fractures resulting in a significant increase in pertrochanteric fractures (AO-31A1+2) (p<0.001). The ratio of trochanteric to neck hip fractures increased from 0.99 to 1.53. Continual monitoring of patients with hip fracture offers data which allows comparisons between regions and countries. The importace of a continual increase in the number of hip fractures has its importance in macroeconomical planning in traumatology. Hemiarthroplasty was conversed to total hip arthroplasty in 12 patients in our department. The indication, time period to conversion and hemiarthroplasty position were retrospectively assessed. The direction of...
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Design of the optofiber sensor system to monitoring change of length
Jelínek, Michal ; Stehlík, Jiří (referee) ; Mikel, Břetislav (advisor)
The bachelor´s thesis deals with design and verification of optical fiber sensor system for measuring changes of length. This system is designed to shape monitoring of the nuclear power plant containment. The principle of measurement, design and realization of the first version is described in the work. Principle of measurement and functionality of the whole system was verified by measurement of specially prepared reinforced concrete console. The console was prepared in the way to simulate behaviour of containment of the nuclear power plant. Within development of system there were prepared of optical fiber sensors with Bragg´s grattings which are later used for measurement.
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Simulation of network structures
Novák, Pavel ; Kalibera, Tomáš (referee) ; Peterka, Jiří (advisor)
The simulation of network structures can be an effective method for example in teaching, research, or testing the network software, in order to lower the cost of building the real network structure that would be otherwise needed. Moreover, the simulated network can provide some advantages, e.g. simplified control and monitoring, statistical data collecting or visualization of the network behavior. This work focuses on the usage for teaching and testing; illustrates that existing network simulators are not always suitable for this purpose, suggests the architecture and design of a new solution, and offers implementation of the proposed simulation tool.
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název v anglickém jazyce není uveden
Klusáčková, Pavlína ; Pelclová, Daniela (advisor) ; Hajduková, Zdeňka (referee) ; Vízek, Martin (referee)
Early diagnosis of occupational asthma is important especially for the prognosis of this disease. The confirmation of the diagnosis of occupational asthma is sometimes difficult using diagnostic methods available nowadays. That is why searching new methods is very important. Analysis of exhaled breath condensate (EBC) by liquid chromatography combined with mass spectrometry enables the separate detection of cysteinyl leukotrienes (LT) - LTC4, LTD4, LTE4; LTB4 and 8-isoprostane. If patients with occupational asthma and controls were compared, only LTC4 was significantly higher among all EBC parameters studied in asthmatics (despite corticosteroid treatment). This marker could be used in the future diagnostics. Monitoring of 24-hours variability of EBC parameters in patients, in whom occupational asthma is suspected, showed relatively high intraindividual and interindividual variation. It is evident therefore, that if only one daily measurement in asthmatics would be possible (which is common in articles of several authors), it should be collected in the same period of day in all persons. In negative bronchoprovocation tests significant changes of EBC parameters were not found. The evaluation of positive bronchoprovocation tests was limited by small number of patients, however in five persons from six, the...
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Application of Critical Chain in IS/ICT Project Management in an IT Company
Šlejharová, Daniela ; Chlapek, Dušan (advisor) ; Vedral, Ladislav (referee)
This thesis deals with application of Critical Chain in IT/ICT Project management in an international IT company. Beginning with a definition of Theory of Constraints and Critical Chain from a theoretical point of view the thesis provides knowledge base for practical implementation of Critical Chain. The thesis proceeds with selection and division of various IT/ICT projects types providing their evaluation according to their usability with CCPM (Critical Chain Project Management). The thesis also contains research and overview of available resources dealing with application of Critical Chain in IT projects management. This research is presented in a form of case studies and also concluded as a summary of both achieved successes and critical success factors that should be taken into account when implementing CCPM. Based on the knowledge acquired from the previous chapters a formal step-by-step procedure defining how to proceed with CCPM in a project was defined. This procedure will be applied in a real project management as a part of this diploma thesis. The thesis also presents analysis of currently used methodology and approaches to project management in the company and using the procedure created in the previous part the methodology is extended by relevant parts of CCPM. These approaches and methodology are formalized in a Methodical Pattern for IS Development (FI) -- CCPM and this pattern is then used for application of CCPM in a software development project. The project is prepared, planned and controlled according to principles of Critical Chain. The thesis captures this process step-by-step including monitoring of the project and its buffers. For evaluation of the Critical Chain implementation in a software development project a set of criteria was developed and used for assessment. Also every member of the given project team was sent a questionnaire to provide feedback. Originally planned comparison of the CCPM project with a project managed by currently used approaches could not, unfortunately, be carried out due to lack of data and their sensitivity. Considering the scope of this thesis, the application of CCPM in a real project represents verification of validity of the Methodical Pattern for IS Development (FI) -- CCPM and the contribution is also in creation of criteria and verification of their usability for evaluation of projects and potential comparison of two or more projects. Based on the practical application of Critical Chain in a real project, suggestions and recommendation for adjustments to current methodology and also further work with CCPM in the company were provided.
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Analysing company's behaviour and communication on social networks
Němec, Milan ; Molnár, Zdeněk (advisor) ; Jelínek, Ivan (referee)
This thesis focuses on measuring company´s communication and behaviour on social networks. To capture the interaction between the company and its users the thesis uses web analytics tools. Therefore, the main objective of the thesis is analysis of these tools. To achieve this goal, the thesis characterizes social networks and their marketing opportunities for business promotion. Thanks to this, needs of using these tools is identified. The needs are: competitive analysis, optimizing communication, measuring achievement of objectives or detection competitive viral content. Research questions were determined and then analysis tools found answers to research questions. It was found that the tools provide various views of data and create a complete system for measuring and analysing behaviour and communication companies on social networks. The results were validated in a case study focused on the Facebook profile of the University of Economics in Prague. The study analysed the interaction profile of the school and its users and compared with others schools. In the results the analysis tools are validated and it is designed recommendation for improve engagement. This thesis revealed strengths and weaknesses of tools for measuring company´s communication and behaviour on social networks. It was found that these tools have wide range of use. They can be used for understanding the company's profile, its users, for purposes of competitive analysis, monitor corporate goals and optimize communications on social networks.
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Monitoring the effect of atorvastatin on the expression of endoglin / / and endothelial NO synthase (eNOS) in mouse model of atherosclerosis
Uhlárová, Iva ; Nachtigal, Petr (advisor) ; Štaud, František (referee)
Atherosclerosis, or sclerosis of arteries, is a degenerative disease of arteries. Sometimes it is called "the disease of 20th century". ApoE/LDL - receptor double knockout mice represent a new animal model for study of atherogenesis, which is characterized by severe hyperlipidaemia and atherosclerosis. Statins (or competitive inhibitors 3-hydroxyl-3-methyl-glutaryl-coenzym A-reductase) currently belong to the most efficient and the most useful hypolipidemic drugs for all over the world. They decrease mainly levels of total cholesterol and LDL cholesterol. The aim of this thesis was to describe the expression of endoglin in atherosclerotic plaques in apoE/LDL-receptor deficient mice. Moreover we wanted to determine endoglin colocalization with eNOS and the effect of atorvastatin treatment on the expression of both molecules. ApoE/LDLR-deficient mice on were subdivided into 2 groups. The control group of animals was fed with the western type diet. The same atherogenic diet was used in ATV group, where atorvastatin was added to the atherogenic diet at the dosage of 100 mg/kg per day. The results of this thesis confirmed the expression of endoglin in atherosclerotic lesions in ApoE/LDLR-deficient mice. The expression of endoglin was located on the aortic vascular endothelium and in other smaller...
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The influence of spinal patients regular training in Locomat System on chosentime and space parametres of their walk
Strnadová, Helena ; Oplatková, Lenka (advisor) ; Strapková, Zuzana (referee)
Diploma thesis "Influence of regular training of spinal cord patients in Lokomat system on particular spatio-temporal parameters of their walk." is a theoretical-empirical case report. Theoretical part deals with the neuroanatomy of the spinal cord, control, analysis and possibilities of check up of physiological walk. This part is concluded by the summary of entries about the Lokomat system, its basic technical equipment, advantages / disadvantages, indications/ contra-indications of its use in practice. The empirical part deals with the examination of the influence of the training in Lokomat system on the walk of the patients with incomplete spinal cord lesion. The main subject of the research is to monitor the changes in particular spatio-temporal parameters of walk (gait speed, stride length, stride time, single support time). Powered by TCPDF (www.tcpdf.org)
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Analysis breeding of milk cattle on the chosen biofarme
Plášková, Pavlína ; Toušová, Renata (advisor) ; Ducháček, Jaromír (referee)
The aim of this thesis is to evaluace the conditions of dairy cattle breeding in ecological agriculture and to compare them with concrete values taken from the chosen ecological farm Bílčice, which has been part of ecological agriculture since 2011 and which is focused on czech fleckvieh breeding and bio milk production. The first part deals with dairy cattle breed characteristic, main objectives and ecological agriculture principals, welfare problems, breed cattle and utility control, housing technology, nutrition and feeding, mechanical milking technology, milk production, reproduction, health condition and breeding economy. The practical part contains the rating of milk yield index (milk production, % proteins, % fat) and reproduction index ( meantime, perioda service, insemination index and after first parturition percentage). 650 pieces of cos were stabled at farm, from that 200 pices of dairy cos were mostly czech fleckvieh. Monitoring was made in 2013. Dayily milk production was around 2 750 kg. The milk utility for lactacion was in 2013 6 100 kg of milk, 3,89 % fat and 3,34 % proteins. The dairy cos were free stabled with high bedding, They were mechanically milked twice a day in herringbone parlours. Milk is being delivered once in twodays to Olma dairy. Cows are regularly driven out to pasture in summer feeding period. They are extra fed with 10 kg of clover silage and 6 kg of scarp (barely, wheat, triticale). Cows stays in stables for winter time. The ration consists of 45 kg of clover silage, 6 kg of scarp, 2 kg of lupine and 1 kg of corn in first time of lactacion. The cow utility in transitional form of economy at farm Bilcice was 7 477 kg of milk in 2010, a value in the Czech Republic was 7 726 kg of milk. After entering the ecological agriculture in 2013 milk yield at the farm decreased on 6 100 kg of milk and the average value in the Czech Republic increased to 8 370 kg of milk. The cow utility in transitional form was 4,03 % fat in 2010 and 3,89 % in 2013 (ecological agriculture). A diference between 2010 and 2013 is 0,14 %. Proteins were 3,39 % in 2010 and 3,34 % in 2013. There was average value for every reproduction index. The service period was 96 days and the meantime was 400 days, the insemination index was 1,8 and the after first parturition percentage was 54,2 %.
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