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Intake of the D vitamin at children at younger school age
PAVLÍČKOVÁ, Adéla
Vitamin D is an integral part of our diet. It is vital for a proper growth and development of a child. It affects development of bones, nervous system activity, neuron creation, and immune system. Currently, around 60% of European children suffer from its deficiency. Insufficient intake of vitamin D from animal sources can be the cause of the deficiency for this group. Up to 90% of vitamin D intake is caused by the sun. Thus, the cause of the deficit can also be the lowered time spent outside. I chose four goals for my bachelor's thesis. The first goal was to ascertain the amount of vitamin D that primary school children intake orally. The second goal I chose was to ascertain the significance of oral vitamin D supplements for primary school children. The third goal was to ascertain the number of products with vitamin D content that primary school children have in their diet. The last goal was to determine what part of dietary reference intake of vitamin D primary school children take in from food. The practical part dealt with the interpretation of the research results. The sample consisted of 20 subjects aged 6 to 12 years old, and the data were gathered in Písek and surrounding areas. The research method I chose was quantitative-qualitative. The data were gathered by questionnaires and menus. The questionnaires helped determine the number of products with vitamin D content that each subject consumed in a week. It also contained a question whether they supplement vitamin D. The menu helped determine the amount of vitamin D taken in from foods in a week. The collected data from menus were subsequently inputted into the Nutriservis software, which calculated the amounts of vitamin D in micrograms from the given foods. From these results, I calculated the overall weekly vitamin D intake and what percentage it made from the weekly oral dietary reference intake of vitamin D. If the subject used supplements, I added it to the calculation of weekly intake and determined the percentage of weekly oral dietary reference intake. The questionnaires indicate that among the most favourite products with vitamin D content are milk and dairy products. Less frequent but also significant are egg yolks and vegetable oils. Liver, however, was reportedly consumed by only three subjects out of 20 on a weekly basis. Based on the results, a conclusion can be drawn - vitamin D supplements play a significant role in the given age group. This claim is supported by the research results, which indicated that none of the subjects would have fulfilled the weekly oral dietary reference intake without vitamin D supplements. Currently supplementing were 8 out of 20 subjects. Seven out of the eight supplementing managed to fulfil the weekly oral dietary reference intake. These results indicate that it is necessary to increase awareness of both children and parents about vitamin D intake.
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Prospective study of adults diet and their vitamin D blood level
HAVLOVÁ, Adéla
Vitamin D is a widely discussed topic in domestic and foreign literature. Vitamin D serves many functions in human body, for example in affects calcium metabolism. Vitamin D is produced photochemically during sun exposure and partly it is consumed with food intake. This thesis is concerned with the problematic of dietary intake of vitamin D. The goal of my research was to analyze a relationship between a specific amount of vitamin D intake with food and vitamin D level in blood in a person. In this research quantitative methodology - prospective method was used. The participants of my research wrote down every meal they ate every day for nine months. They specified amount and kind of consumed food intake. Participants blood was analyzed for levels of calcidiol, alkaline phosphatase, calcaemia and phosphataemia. The blood was taken twice during the research. The number of participants involved six women and three men. The research started on 1 March 2021 and lasted until 30 November 2021. The participants from the research had no record of gastrointestinal diseases, this could affect vitamin D absorption from dietary intake and that could lead to biased results. This research was led as a blinded experiment to prevent experimental bias. It was important that the participants did not consume higher or lower amounts of vitamin D on purpose. Each participant followed regular assorted diet and did not restrict oneself in food intake. The results showed that participants of this study consumed more vitamin D in their diet on weekends rather that in a regular day. It was further discovered that in spring vitamin D blood level correlated with the amount of consumed vitamin D in diet. Median value of vitamin D intake in diet for one participant was 2,268 g per day, average value was 3,55 g per day. Based on the evaluated participants lists of meals was discovered that the amount of consumed vitamin D in diet made 17,75 % of its guideline daily amounts.
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Vitamin D blood level and its relationship to recurrent childhood diseases
HAVLOVÁ, Adéla
"Vitamin D blood level, factors that affect it, and its relationship to reccurent infections" is topic repeatedly discussed in domestic and foreign literature. This topic is a multidisciplinary issue, but it mainly relates to nutrition and sun exposure. The aim of this study is to map relationship of vitamin blood levels in relation to diseases of the respiratory system, vitamin D suplementation, recurrent infections, usage of sunscreen with a protective factor, nutrition and outdoor stay in winter months. The study was conducted on a research sample of preschool children. Two sets of data were used to evaluate objectives and research questions. The first research group consisted of 48 children and had 2 groups. The first group of 21 children was established in the Waldorf kindergarten in Rudolfov and the second group of 17 children was created in a non-state medical facility in Trebon. The first research consisted of 48 children who were tested on vitamin D blood level and filled survey questionnaire. The second research consisted of 61 children who were tested on vitamin D blood level in a non-state medical facility. Some results of this study are contradictory because of inadequate methodology. Positive results have been shown with vitamin D supplementation, higher consumption of liver, eggs and daily intake of vegetable oils.
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The monitoring of vitamin D content in the diet of university students
KALETOVÁ, Nikol
The aim of the diploma thesis was to evaluate the level of vitamin D saturation in a selected group of university students at the University of South Bohemia in České Budějovice. The recorded diet method was used for the research. The research group included six men and six women aged 19-26. The research ran from the 10th February to 14th June 2020. Respondents recorded a week-long diet every second week in February, April and June. This captured possible seasonal fluctuations in the diet. Respondents recorded the amount and type of food and meals consumed. In the monitored group of respondents, vitamin D values averaged around 4.86 g per person per day. The values obtained do not correspond to the recommended daily intake of vitamin D, which according to DACH (2018) should be 20 ?g per person per day for men and women of this age category. In the group of women, the average intake of vitamin D was 3.88 g / day and in men the intake was higher, namely 5.85 g / day. The obtained levels agree with the results of other authors. Alimentary intake of vitamin D is usually in the range of 2-4 g / day, which is confirmed by the results of the diploma thesis. The lowest average daily intake was found in women to be 2.81 ?g / day and the maximum value in men on average 11.26 g / day. This value is at the level of 50% of the recommended daily intake. The main statistical finding was to demonstrate a difference in vitamin D intake between the gender. Men took more vitamin D than women. Furthermore, a positive relationship between protein and vitamin D intake was demonstrated. Last but not least, the effect of gender on protein intake was statistically significantly demonstrated. Men received more protein than women. The question dealing with the effect of the season on the intake of vitamin D from the diet has not been significantly statistically proven. In the second part, the energy intake and main nutrients were also determined, which according to the final evaluation were very unbalanced.
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Functional fitness and Vit. D levels in patients with hepatopathy
Brtková, Helena ; Novák, František (advisor) ; Meisnerová, Eva (referee)
Introduction: patients with hepatopathy are at risk of vitamin D deficiency. Vitamin D levels affect, among other things, metabolism and physiological functions of muscle tissue and thus functional fitness. The aim of this study is to assess muscle mass and strength in relation to vitamin D levels and other factors that affect functional physical fitness in patients with cirrhosis, compared to a control group of patients without hepatopathy and other chronic comorbidities. Methods: 11 patients with liver cirrhosis were enrolled in an observational cohort study compared with 11 controls without chronic comorbidities. Anthropometric and bioimpedance measurements were performed, functional tests, the 6MWT 6-minute walk test, hand grip strength assessment and calorimetry examination were also evaluated, and laboratory parameters were assessed. Study participants completed the CLDQ test, which assessed the quality of life of people with liver disease. Respondents answered questions regarding lifestyle, eating habits, physical activity and functional physical fitness. For patients with cirrhosis, the Child Pugh score and MELD score were used to assess the progression of cirrhosis. Results. At the time of the study, the vast majority of patients had a compensated form of liver cirrhosis, Child Pugh A...
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The toxicity of vitamin D
Drouliskou, Eleftheria ; Mladěnka, Přemysl (advisor) ; Janoušek, Jiří (referee)
Vitamin D has essential role in skeletal health, however studies over the recent years have outlined its implication in many other physiological functions. The importance of vitamin D for health has, on one hand, raised needs for supplementation but may, on the other hand, lead to excessive administration. Vitamin D toxicity or hypervitaminosis D due to excess of vitamin D is a medical condition manifested mainly as hypercalcemia, with mostly gastrointestinal and neuropsychiatric symptoms. Long-term administration of large doses of vitamin D can result in vascular calcification and hence by associated with a cardiovascular risk. Hypervitaminosis D is extremely rare likely due to high therapeutic index of vitamin D. The clinical research shows an administration of 10.000 IU/day of vitamin D, which meets the criteria for the tolerable upper intake level, even for extended period, is probably not associated with adverse effects in almost all individuals in general population. However there are case studies globally showing vitamin D toxicity can occur due to misuse of over-the-counter vitamin D supplements, inappropriate prescribing or uncontrolled administration of high dose unlicensed preparations.
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Adherence to calcium and vitamin D supplementation in women with postmenopausal osteoporosis
Holcová, Radka ; Vytřísalová, Magda (advisor) ; Fuksa, Leoš (referee)
Adherence to calcium and vitamin D supplementation in women with postmenopausal osteoporosis Author: Radka Holcová Supervisor: Magda Vytřísalová Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy Introduction: The insufficient medication adherence is a very frequent problem with chronic asymptomatic diseases as osteoporosis which significantly influences the treatment outcome. The successful osteoporosis therapy is based on adequate supply of calcium and vitamin D. A lot of studies are focused on the adherence to antiresorptive treatment but the adherence to supplementation therapy is rarely evaluated. Aims: The aim of the study was to evaluate the adherence to calcium and vitamin D supplementation in women with postmenopausal osteoporosis. Methods: The adherence was evaluated using two different methods: self-reported questionnaire and the electronic monitoring by bottles type Medication Event Monitoring System (MEMS). This partial analysis of a multicentre study includes and assesses data from Osteocentre in Pardubice Regional Hospital. Results: The analysis was performed with 15 women (the average age of 73). The patients were treated with Caltrate 600 mg/400 IU D3 once a day for three months. The adherence during the entire period...
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Hypertension and Nutrition: Fat-soluble Vitamins A, D and E
Weber, Jakub ; Vlček, Jiří (advisor) ; Hronek, Miloslav (referee)
Hypertension and nutrition: Fat-soluble vitamins A, D and E Weber J1 , Vlcek J1 , Suarez-Varella MM2 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech Republic 2 Department of Preventive Medicine and Public Health, Faculty of Pharmacy, University of Valencia, Spain Arterial hypertension (AH) is a disease affecting population globally, and thus considered as a problem of public health and socioeconomic. Studies are trying to identify the connection between diet and the prevalence of arterial hypertension. Objective of the study was to determine possible association between an occurrence of AH and fat-soluble vitamins A, D and E intake. The nested, case-control population study investigation was grounded on database from the Spanish Hortega study, and performed on a random sample of 1,514 people (50.3 % women, 49.7 % men). From this sample we selected those aged ≥ 40 years old and untreated for hypertension and divided them into two groups: non-hypertensive (n = 429; 63.6 %) (controls), and newly diagnosed AH (n = 246; 36.4 %) (cases). Biochemical and anthropometric measurements, data on dietary intakes, education, socioeconomic status, place of residence, health habits, comorbidities, consumption of alcohol and tobacco were used for our...
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Multidisciplinary rehabilitation for pubescents patients with cerebral palsy
Buzková, Tereza ; Nývltová, Lucie (advisor) ; Zounková, Irena (referee)
Cerebral palsy is a non-progressive motor funciton development disorder which is caused by disruption of the immature brain. There is about 16 000 - 20 000 patients living in the Czech Republic with this diagnosis to date. Based on the clinical picture, specific forms of this disorder can be classified. Besides the motor funciton development disorder, the patients also suffer from other comorbidities (such as epilepsy, oropharyngeal dysphagia, sensory deficits etc.). Early diagnosis of this disorder is crucial. The severity of the motor function deficit is evaluated by monitoring the gross and fine motor function. Cerebral palsy is a non-progressive, not unchanging, disorder. The theoretic part of the thesis describes secondary issues which are present during pubescent period of the patients. They are dealing with growth disorders, reduced bone density and increased bone fragility. Plenty of risk factors precede these problems. Also, question of sexuality, life priorities and about future play a big role for the patients in their pubescent period. There are possibilities to solve these problems in terms of complex rehabilitation care. Especially in physiotherapy, occupational therapy and nutritional therapy. The practical part of the thesis is an example of an intensive rehabilitation care of a...
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