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Quality of Life, Adherence and Satisfaction of Patients with Aquired Brain Injury in Distance Occupational Therapy and Tele-occupational therapy
Bartošová, Simona ; Hoidekrová, Kristýna (advisor) ; Jelínková, Jana (referee)
Author of diplom thesis: Bc. Bartošová Simona Thesis supervisor: PhDr. Kristýna Hoidekrová Title of diplom thesis: Quality of Life, Adherence and Satisfaction of Patients with Aquired Brain Injury in Distance Occupational Therapy and Tele-occupational therapy. Abstract of diplom thesis: The thesis (DP) deals with the issue of patients after acquired brain injury in distance occupational therapy and tele-ergotherapy. The main aim of the DP is to evaluate the quality of life, adherence and satisfaction of patients after acquired brain injury during distance occupational therapy and tele-ergotherapy. The thesis is divided into two parts, theoretical and practical. The first, theoretical part is based on the studied Czech and foreign literature. It deals with a short description of the individual types of acquired brain damage, rehabilitation in patients after acquired brain damage andthepossibility ofusing telerehabilitation (TR) and distancetherapy in occupational therapy in these patients. The development of the practical part is carried out in cooperation with the Rehabilitační Ústav Kladruby (RÚ Kladruby), where the Virtual Ambulance Distance Therapy (VA- DT) project has been running since January 2019, offering distance therapy and telerehabilitation. The research sample consists of 7 patients...
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Effect of storage of biological material on the activity of biotransformation enzymes
Jelínková, Jana ; Szotáková, Barbora (advisor) ; Kvasničková, Eva (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Jana Jelínková Consultant: Doc. Ing. Barbora Szotáková, Ph.D. Title: Effect of storage of biological material on activity of biotransformation enzymes Effect of storage of liver and subcellullar fractions on the activities of biotransformation enzymes was studied. Activities of oxidation enzymes - cytochromes P450 (CYP1A, 2B, 2C, 3A) and flavin-containg monooxygenases (FMO), carbonyl-reducing enzymes (AKR1A1, AKR1C, 11β-HSD,CBR) and conjugation enzymes (UGT, GST) were observed. Microsomal and cytosolic subcellular fractions prepared from differently stored liver of sheep (Ovis aries) were used. (A) from fresh tissue frozen in the liquid nitrogen. (B) from liver that was stored at -80C, the temperature gradually increased to 0C and then gradually decreased back to -80C. The half of prepared microsomal and cytosolic subcellular fractions from liver stored in liquid nitrogen (A) was processed by the same storage procedure as liver (B). The second half was stored at -80C. Activities of tested biotransformation enzymes were determined toward their relatively specific substrates. The subcellular fractions were also incubated with xenobiotics (oracin, flubendazole and albendazole) and the...
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