|
|
n-3 polyunsaturated fatty acids in prevention of cardiovascular diseases
Pavelka, Jan ; Kraml, Pavel (advisor) ; Černá, Milena (referee)
Clinical trials have documented beneficial effect of n-3 polyunsaturated fatty acids on health. Regular dietary intake of n-3 PUFAs decreases the risk of cardiovascular dieseas. n-3 PUFAs may be a safe and effective supplement to drug treatment for reducing the risk of myocardial infarction, arrhythmia and sudden cardiac death. n-3 PUFAs show antiatherogenic properties; e.g. they decrease inflammation, stabilize atherosclerotic plaques and prevent other chronic deseases. For primary prevention it is recommended to eat fish at least twice a week, people with documented coronary heart disease should consume 1 gram of n-3 PUFAs daily. Fish oil and oily fish (losos, tuna, trout, mackerel) are rich in EPA and DHA. ALA is found e.g. in flax seed oil.
|
|
|
Vlčí důl old ecological burden, its possible health risks and Zásmuky citizens situation knowledge
Jiráková, Pavla ; Rödlová, Sylva (advisor) ; Černá, Milena (referee)
Bachelor thesis deals with problems of ecological burdens with focus on specific location Vlčí důl near Zásmuky. The theoretical part contains a general introduction to define ecological burden, historical and legislative requirements up to possibilities their elimination. Other chapters describe Aroma, a originator of contamination in Vlčí důl, the possibilities of health risks and the ecological burden itself in the Vlčí důl. The practical part includes the health effects of individual chemicals substances are situated in location Vlčí důl, general knowledge and attitudes of residensts of Zásmuky and associated municipalities to this area, which were analyzed using text analysis and questionnaire survey. Ecological burdens are comming mainly from the second half of the 20th century are a lot and the financial resources, are few owing them would the situacion to solve. Except for financial page, the political page also plays a role in solving the elimination of ecological burdens.
|
|
|
Perioperative prognostic factors in breast cancer
Černá, Monika ; Třeška, Vladislav (advisor) ; Gaťek, Jiří (referee) ; Šiller, Jiří (referee) ; Jandík, Pavel (referee)
Introduction: Breast cancer still remains the most common malignancy in women and its incidence is slowly increasing. A marked reduction of mortality has been achieved in the last 10 years thanks to modern diagnostic methods, mammary screening, and comprehensive and targeted cancer therapy. Modern diagnostic capabilities not only allow early diagnosis of a primary tumor lesion and precise determination of its biological nature before commencing treatment, but they also enable early diagnosis of local and regional recidives, including diagnosis of metastases in distant organs. In addition to clinical examination, conventional and complementary imaging examinations and tumor markers our objective was to determine the importance and use of growth factors in relation to the overall prognosis. The growth factors physiologically act already during the ontogenetic period when they control cell growth, proliferation, differentiation and apoptotic processes. It is known that they take part in the tumor growth processes which are characterized by autonomous behavior, increased proliferative activity, distinct differentiation activity and reduced apoptosis. Growth factors work as autoregulation factors in the neoplastic process as well as through their paracrine effects mediated by more or less specific receptors....
|
|
|
Patients and obstetricians attitudes associated with cesarean delivery on maternal request
Baxová, Anna ; Křepelka, Petr (advisor) ; Černá, Milena (referee)
Cesarean delivery on maternal request is one of the most discussed questions among obstetricians all around the world. It is a situation when mother wishes to have cesarean delivery although no indications for this surgery are presented. The aim of this diploma paper is to provide important facts about epidemiology, indications and complications of cesarean section and discuss obstetricians' and professional associations' opinion on cesarean delivery on maternal request, its' health, psychological, social and ethic aspects. In the practical part the results of the questionnaire survey are provided, in which we asked about the attitudes of patients and obstetricians towards cesarean delivery on maternal request and other associated questions.
|
|
| |
|
|
Molecular aspects of calcium-phosphate metabolism in renal complications of diabetes mellitus.
Šimáková, Eva ; Černá, Marie (advisor) ; Zajíčková, Kateřina (referee)
Introduction: This thesis deals with the calcium-phosphate metabolism and its role in the development of chronic diabetic complications. It examines calcium sensitive receptor, which can be crucial in affecting calcium metabolism. Calcium-sensitive receptor may play a role in intracellular signaling and metabolic pathways that lead to cell proliferation and extracellular matrix early diabetic nephropathy. We investigated two polymorphisms of the gene for calcium-sensitive receptor (intron 4 and codon 990). Material and Methods: The study included 313 diabetic patients, 41 patients with type 1 diabetes, 106 patients with type 2 diabetes, 110 diabetic patients with type 2 diabetes who had diabetic nephropathy and 56 patients with renal failure non-diabetic (NDRD). It was also examined 72 non-diabetic patients with chronic renal failure (CKD) and 96 healthy blood donors (ZK). Classification of diagnoses is listed in the theory. DNA was isolated by QIAamp DNA Blood Mini Kit and salting method. The specific fragments of gene for the CaSR were amplified by PCR. For detection, restriction fragment length polymorphism and TaqMan probes were used. The expression levels of mRNA were determined by real-time PCR. Results: For the codon 990 polymorphism, we found statistical significance of the genotype frequencies (AA,...
|
|
|
Golden section around us
Černá, Michala ; Zhouf, Jaroslav (advisor) ; Dvořák, Petr (referee)
This bachelor thesis deals with the golden section. This a guided background research already represents a cross-section of the currently available literature. The term golden section is first defined. Subsequently, the states in which forms can appear golden section (eg Fibonacci sequence, golden rectangle and other geometric shapes that are closely related to the golden section). The very essence of the work is to inform the reader with the disciplines in which we can meet the golden section. The two largest sectors are nature and art, which are further subdivided into other sectors. Degree of difficulty of the document is adapted to a wide scope of potential readers. The aim is to create a comprehensive set of disciplines related to the golden section. Contribution of the thesis is critical and factual insight into the problems of the golden section, which is interested in literature rarely about. Key words: Golden section, number Fibonacci sequence
|
|
| |
|
|
The origin and the development of selected specialized and scientific libraries on the territory of the Czech state until 1918
Šrámek, Jan ; Černá, Milena (advisor) ; Vášová, Lidmila (referee)
Tématem práce je shrnutí dějin vybraných odborných a vědeckých knihoven na území českého státu do roku 1918. Práce se zaměřuje na tyto knihovny: knihovnu Národního muzea, Státní technickou knihovnu v Praze, Státní vědeckou knihovnu v Olomouci, Státní vědeckou knihovnu v Brně (dnešní Moravská zemská knihovna); knihovnu Akademie věd a Veřejnou a univerzitní knihovnu v Praze. Cílem práce je deskriptivní metodou shrnout poznatky o vzniku a vývoji daných knihoven, práce se dále věnuje podmínkám, za kterých knihovny vznikaly, shrnuje poznatky o vývoji jejich fondu a o významných osobnostech, které jsou s danými knihovnami spjaty. V závěru kapitol je nastíněn vývoj jednotlivých knihoven po roce 1918.
|
|
|
The structure of the Municipal Library in Děčín and its services for users
Bednářová, Vendula ; Vášová, Lidmila (advisor) ; Černá, Milena (referee)
(anglicky) The main purpose of this bachelor thesis is to describe the establishing of the Děčín library as well as its organizational structure and services. The first chapter is about the history of the town and its cultural background. The second chapter is about historical development and the current state of library - its organizational structure, equipment and financing is described at the third chapter. All library departments, library services and library collection are described in the fourth part. The last chapter is about library's educational center and the construction of the new library building.
|
guest ::
RSS feed.