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Exercise, side effects of anti-epilepsy drugs and quality of life in patients with epilepsy
Šimonová, Lucie ; Javůrková, Alena (advisor) ; Vogner, Martin (referee)
Background: This bachelor's thesis examines the relationship between physical activity and sociodemographic variables, clinical variables of epilepsy, anxiety, depression and attentional executions, and adverse effects of ASM. Aims: The aim was to investigate how patients who have physical activity differ from those who do not on sociodemographic variables, clinical variables of epilepsy, adverse effects of epilepsy, anxiety, depression and attentional executions, quality of life and adverse effects of ASM. Methods: 235 patients were included in this retrospective cross-sectional study. Patients were examined at the Centre for Epilepsy Treatment, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital. Dg. of epilepsy was determined by a physician. All patients signed the IS and the research was approved by the EC. Descriptive statistics (mean, standard deviation, median, minimum, maximum, absolute and relative frequencies) were used to describe the variables. Spearman's correlation coefficient, Student's t-test, and Kruskal-Wallis test were used to analyze the hypotheses and ANOVA was used.Chi-square test was used for discrete variables and logistic regression was used to estimate odds ratio (OR). Results: We were able to demonstrate a relationship...
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Experiences of SARS-CoV-2 patients hospitalised in an ICU
Korčáková, Ester ; Rambousková, Kateřina (advisor) ; Javůrková, Alena (referee)
The present thesis focuses on the experiences of patients hospitalised with the SARS-CoV-2 disease within the intensive care settings. It examines the influence of the hygiene- epidemiological regime and protective medical equipment on the patients'experience of hospitalisation and their effects on their psychological well-being. The theoretical part summarises the basic information about the virus causing the disease, the causative agents, clinical manifestations, and treatment methods. It indicates the specifics of the intensive care unit, preventive measures and hygiene and epidemiological principles. In addition, it states the general principles of care for patients with Covid-19 and discusses the disease in intensive care. Finally, the effects of hospitalisation on the psychological well-being of the patients and the post covid syndrome are discussed. The practical part of the thesis maps the patients' preception and experience of hospitalisation, the hygiene and epidemiological regime, and the protective equipment of the staff. The research was carried out in the form of interviews with nine patients from three health case institutions, the University Hospital Královské Vinohrady, the University Thomayer Hospital, and the Klaudián Hospital in Mladá Boleslav. Keywords: Covid-19, SARS-CoV-2,...
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Association between physical activity, quality of life, depression, anxiety, and cognitive state in patients with epilepsy
Žížalová, Johana ; Javůrková, Alena (advisor) ; Vlček, Přemysl (referee)
Introduction: The quality of life of patients with epilepsy (PWE) is affected not only by recurrent seizures and associated limitations, but also by frequent psychiatric comorbidities and cognitive problems. At the same time, these patients are more prone to a sedentary lifestyle compared to the general population, which can lead to further health disadvantages. Aim: The aim of this bachelor thesis was to investigate the relationship between physical activity and quality of life, depression, anxiety, and cognitive state in PWE. Methods: Data on physical activity (type of activity, number of hours per week, frequency per week), quality of life (Quality of Life in Epilepsy Inventory, QOLIE-89), depression (Beck Depression Inventory, BDI-II), anxiety (Beck Anxiety Inventory, BAI; Generalized Anxiety Disorder, GAD-7) premorbid intellect (Czech Reading Test, CRT), and executive functioning and attention (EpiTrack) were obtained from 134 PWE at the Centre for Epilepsy Motol of the Neurological Department of 2nd Faculty of Medicine of Charles University. Results: Of 134 PWE, only 33% met WHO recommendations for physical activity. Compared to inactive PWE, these patients had a higher quality of life (QOLIE-89), higher premorbid intellect (CRT), scored better on the executive function and attention test...
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The quality of children's life following burn injury
Duchoň, Jan ; Javůrková, Alena (advisor) ; Jirkovský, Daniel (referee)
Background: The bachelor's thesis deals with the assessment of the long term health- related the quality of life (HRQOL) in children up 2 to 8 years of age following burn inury by The Brisbane Burn Scar Impact Profile (BBSIP) questionnaire in the Czech Republic. Objectives: The aim of the theoretical part of this thesis was to provide a review of the literature and individual studies about HRQOL in children following burn injury and its context. The aim of the empirical part was to assess the influence of individual socio- demographic and clinical determinants on the HRQOL in these patients, identify, which of these variables most predict the HRQOL and implicate these findings into the context of nursing practice regarding comprehensive care for pediatric patients with burns. In this study we also examined the psychometric properties of the czech version of the BBSIP questionnaire on a sample of pediatric patients in the Czech Republic. Methods: The study population comprised n = 1221 children aged up 2 to 8 years, who were hospitalized at the Department of Burn Medicine, 3rd Medical Faculty, Charles University and the Královské Vinohrady University Hospital in the period 2016-2021 and met inclusive and exclusive criteria. A set of BBSIP, POSAS and PedsQL questionnaires was sent to all caregivers...
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Influence of Religiosity on Quality of Life of patients with Epilepsy
Kolská, Marta ; Javůrková, Alena (advisor) ; Nikodemová, Hana (referee)
Objectives: The aim of this thesis is to investigate how the variables Locus of Control, God Locus of Health Control and religiosity predict the quality of life of patients with epilepsy and whether these variables differ in prevalence in a healthy control group. Methods: The research group consisted of 275 patients with epilepsy examined within the neuropsychological Centre for the Treatment of Epilepsy of the Department of Neurology, 2nd Medical Faculty and Motol University Hospital. The comparison group consisted of a group of 182 healthy respondents. Respondents were interviewed using WAIS-III, EPQ R abbreviated version, BDI-II, VAS, QOLIE-89 (version 1.0) and GLHC. The t-test and the Mann-Whitney test were used to determine differences between groups. Contingency tables were used for discrete quantities. The relationship between the variables was demonstrated by Spearman's correlation coefficient and multiple linear regression. The research was approved by the Ethics Committee of the Motol University Hospital. Results: The resulting model of stepwise linear regression prediction of the Mean score showed that by including the variables Neuroticism HS and GLHC˃6 in the overall model, these significant variables can explain 21.44 % variability of Locus of control (R2=0.2144). It was also found...
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Quality of life and pain in patient with epilepsy
Došlová, Dana ; Javůrková, Alena (advisor) ; Nikodemová, Hana (referee)
Bacground: The bachelor thesis deals with the subjective and objective evaluation of the relationship between pain and quality of life in patients with epilepsy based on the questionnaire survey Quality of Life in Epilepsy Inventory (QOLIE-89), Visual Analogue Scale (VAS). Objectives: The aim of this qualitative study is to assess the relationship between pain and quality of life in patients with epilepsy based on scoring in the scale Pain in the questionnaire QOLIE-89 and examination of pain intensity using VAS, validation of results in the examined patient sample, assessment of pain presence and intensity and others. cognitive, affective and functional variables depending on sociodemographic and clinical variables., determining whether pain is a variable that significantly predicts quality of life in patients with epilepsy. Early understanding of the relationship between pain and quality of life helps to set up appropriate nursing care and to ensure a better quality of life for patients with epilepsy. Methods: The study population comprised 150 patients from the Center for Epilepsy Treatment of the Neurological Department 2nd Medical Faculty Charles University and the Motol University Hospital, who met inclusive and exclusive criteria. All patients were examined neurologically and...
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Needs of patients and carers in palliative care
Oktábcová, Marie ; Mádlová, Ivana (advisor) ; Javůrková, Alena (referee)
The bachelor thesis deals with the needs of patients and caregivers in palliative care. The theoretical part defines the concept of palliative care, the forms of its provision and the specifics of the work of a nurse in palliative care. A separate chapter is devoted to needs and their evaluation. The aim of the work is to use a standardized questionnaire IPOS (Integrate Palliative Outcome Scale) to find out what are the differences in perceptions of needs between patients and their caring family members, as well as between patients and caring professionals - general nurses. It was found that the needs of patients are assessed by their caregivers differently from patients themselves. The biggest discrepancy between the assessment of patient's needs and caring family members were on the area of physical needs, specifically in the question of pain or dryness in the mouth. The biggest discrepancy between the evaluation of patients and nurses was in the psychological needs, in particular the level of depression. Professionals have evaluated the palliative patient needs better than caring family members. However, none of the nurses and families answers to the standardized questionnaire were 100% in agreement with patient responses. Use of a measuring tool to assess the needs of patients in the palliative...
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Validization of emotional visually analog screening in epilepsy patients
Muroňová, Eliška ; Javůrková, Alena (advisor) ; Bezdíček, Ondřej (referee)
The thesis deals with epilepsy, its two most common psychiatric comorbidities, and the possibilities of screening and diagnosis of these comorbidities. The literature review section introduces the reader to epilepsy, the classification of depressive and generalized anxiety disorders, their relationship to epilepsy, and currently used methods for screening these mental illnesses. The last chapter introduces the reader to the Emotional Thermometer Method, its origins and development, and the work published to date on the use of this method in people with epilepsy. The research part aims to validate the criterion validity of the Emotional Thermometer for depression and anxiety screening and its comparison with conventional methods BDI-II and GAD-7, using as a reference method the sub-modules of M.I.N.I., the gold standard based on the diagnostic criteria of DSM IV and MKN-10. Another aim is to identify potential risk factors for anti-seizure medication use and sociodemographic and clinical characteristics in epilepsy. The study includes a total of 222 individuals with epilepsy. The results based on ROC curve analysis indicate good results in terms of concurrent validity of the Emotional Thermometer and the suitability of its use for screening depression and anxiety in people with epilepsy as part of...
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Resilience in nurses during the COVID-19 pandemi
Jakeš, David ; Tichotová, Sylvie (advisor) ; Javůrková, Alena (referee)
This paper deals with the phenomenon of resilience, which is receiving more and more attention in the foreign literature. The subject of the theoretical part is to introduce the concept of resilience and its development. The thesis describes how people react and continue after encountering an adverse situation. It also discusses the factors involved in this process. The theoretical part concludes with an overview of the possibilities of measuring resilience. The research design is set in the context of the COVID-19 pandemic, specifically in nurses caring for patients with this disease. It aims to determine the overall level of resilience in this profession in the Czech Republic using the Connor - Davidson Resilience Scale (CD - RISC) questionnaire and then to identify protective factors through a semi-structured interview. Keywords Resilience; Adversity; Factors; Measuring; CD - RISC; COVID-19
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Meaning of a psychedelic experience in cancer patients
Borská, Karolína ; Kočárová, Rita (advisor) ; Javůrková, Alena (referee)
This bachelor thesis explores the topic of psychedelic substances, the meaning of experience with these substances and its impact on experiencing the diagnosis in cancer patients. The literature review section first introduces psychedelic substances and their mechanism of action, with attention also given to the context of psychedelic experience with its risks and general safe use of the substances. It further discusses the phenomenology of psychedelic experience and therapeutic potential of psychedelic substances. The following chapter focuses on cancer and its impact on mental individual's psyche, along with possible therapeutic approaches to such patients. The thesis integrates these two subjects and maps the available knowledge on the psychedelic experience in individuals with cancer and other life-threatening conditions. The research project proposal explores the potential relevance of the psychedelic experience, specifically in population of patients diagnosed with cancer. The research is designed as qualitative in nature, based on selected findings outlined in the literature review section. The aim of this research project is to examine the questions whether and what importance and meaning cancer patients attach to their experience with psychedelic substances in connection with their disease.
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