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The effect of MDOC on testicular tissue II. Intratesticular application of a medicament with MDOC
Havlová, Martina ; Semecký, Vladimír (advisor) ; Herink, Josef (referee)
1 Abstract The aim of my rigorose work was to inspect and assess the effects of time and application of calcium/sodium salt of microdispersed oxidised cellulose (MDOC) to the structural components of testes, especially in the time after an operational localization of one testis into the intraabdominal cavity. We used a model of an experimental unilateral cryptorchidism in the adult male Wistar rats. The surgery was performed under standard conditions using a method introduced in the Department of Biological and Medical Sciences of the Faculty of Pharmacy Charles University. The rats were killed by overdosage of aether aenesthesia and the bilateral testes were removed. The tissues were immediately histologically processed. After the histological modifications we tained the sections with hematoxylin - eosin, green trichrome, Periodic acid Schiff and toluidin blue histological stainings. The evaluation was histological with optical microscope. We compared our results with studies, which are described in the theoretical introduction of my work. In the preparations from the time interval of 7 days after surgery with injection application of 1% solution of calcium/sodium salt of MDOC under the tunica albuginea we randomly measured the diameter of the seminiferous tubules. The diameter of the tubules that...
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VCL Components for Vector Graphics in the Instruction of Chemistry
Adamec, Martin ; Cihelník, Simon (advisor) ; Havlová, Michaela (referee)
Předmětem práce je zhodnocení problematiky vzorců ve výuce organické chemie na střední škole, zhodnocení současného stavu softwaru pro kreslení chemických struktur a vývoj VCL komponent pro chemické kreslení. V současnosti dostupný software je na vysoké odborné úrovni a v chemické praxi má široké použití, nehodí se však pro použití ve výuce na druhém a třetím stupni. Výsledkem práce jsou komponenty pro vytváření, zobrazení a manipulaci s chemickými vzorci jednoduchých organických látek v souladu s požadavky střední školy Součástí práce je také aplikace ukazující základní vlastnosti vyvinutých komponent. Kom- ponenty i aplikace jsou vytvořeny v prostředí Borland Delphi 2005. CD s elektronickou verzí textu, zdrojovými kódy komponent i aplikace a spustitelnou verzí aplikace je přiloženo.
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Teaching the theme human parasites on grammar school.
Houšková, Barbora ; Janštová, Vanda (advisor) ; Havlová, Michaela (referee)
Nowdays, when people travel all around the world and they can become infected with different parasites, teaching about human parasites shouldn't be neglected even in education on primary and grammar schools. In my work, I have mapped the basic knowledge of parasitology and human parasites of students from the selected primary schools and lower grades of grammar schools. For this purpose, I have created a test which examined the knowledge and attitude of the students. The work has also sought to propose a new approach to teaching of the subject in biology lessons. Two different teaching concepts were tested and compared in two paralel classes of the same grammar school. Presented representatives of human parasites, were chosen on the basis of analysis of biology textbooks for basic schools. Final suggestion of teaching at schools, which was teste dat three schools contains powerpoint presentations suitable for use in the lessons and practical exercise taken like didactical games.
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Changes in rat testicular histomorphology induced by unilateral cryptorchidism.
Havlová, Martina ; Semecký, Vladimír (advisor) ; Langr, František (referee)
Martina Havlová Změny histomorfologie varlete potkana navozené unilaterálním kryptorchismem. Abstrakt Cílem této diplomové práce bylo sledování účinku intratestikulární aplikace 1 ml 1 % roztoku xenobiotika sodno-vápenaté soli mikrodispersní oxidované celulosy (MDOC) na struktury zárodečné tkáně varlete laboratorního potkana v krátkém období po operativním umístění jednoho varlete intraabdominálně. Použili jsme tak model experimentálního unilaterálního kryptorchismu u dospělých samců potkana kmene Wistar, který byl jako metoda zaveden a je užíván na pracovišti Katedry biologických a lékařských věd.U každé operované skupiny byla provedena u jednoho zvířete kontrolní slepá operace.Varlata lokalizovaná abdominálně i ve fyziologické poloze byla po usmrcení pokusných jedinců odebrána na histologické zpracování pro účely světelné mikroskopie v časových intervalech 1 , 24 , 48 hod. a 6 a 7 den po operaci.Parafinové tkáňové řezy byly barveny hematoxylin - eozinem, zeleným trichromem a PAS reakcí a byly zdokumentovány a vyhodnoceny pomocí mikroskopické obrazové analýzy. První projevy desintegrace germinativního epitelu jsme zaznamenali u abdominálně reponovaných varlat již po jedné hodině od operace a aplikace MDOC.V intervalu 24 a 48 hodin byl již germinativní epitel abdominálních varlat oproti fyziologicky...
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Use of model ecosystems near Chomutov in basic education
Řeháková, Tereza ; Havlová, Michaela (advisor) ; Drda Morávková, Alena (referee)
This paper focuses on the teaching of eco-tour by cyclo around Chomutov in basic education. The main objective of my DP is a cycling tour with a focus on the comparison of selected characteristics of ecosystems occurring in the area. As I chose the selected ecosystems - meadows and pastures, forests and water bodies. Selected location near Chomutov offers direct observation of these ecosystems provide a number of paths for nontraditional ways of teaching, using bicycle wheels. Developed materials include design incentive hours for after-school teaching materials in the field and the draft final hours. For after-school education in the field are handled by individual worksheets ecosystems - meadows and pastures, forests and water bodies. Besides these main worksheets, I created a set of other activities in the outdoors. They are practicing first aid package of games and competitions designed for environments and other attractions that can fill the time spent in nature. Next, I created a complete methodological guide for teachers, which are summarized in detail all the information for planning, progress and completion of the excursion. Excursions and its content complies with the current general education program for primary education in the country. Keywords: tour, cycling tours, ecosystems, Chomutov
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