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Marketing and business ethics in branches protected by copyright
Černý, Michal ; Johnova, Radka (advisor) ; Bláha, Václav (referee)
The thesis is focused on an analysis of marketing tools and business policies, applied on the field of commercial publishing. First part is dedicated to an analysis of the copyright law that affects the activity of this sort of companies. It includes an explanation of the most important parts of the copyright law that is valid in the Czech Republic. There is a display of important international standards, considering the issues of intellectual property. The second chapter relates to the theory of marketing and ethical issues of commercial and business activities. It includes a definition of basic terms, marketing tools, and a step-by-step clarification related to developing a marketing strategy. The end of this chapter summarizes the options of using marketing tools in publishing. Eventually, the thesis deals with pieces of knowledge, gained during its writing. Two different ways of creating a marketing strategy for the Knižní klub publishing company are considered in the end of the thesis. Both ways are described in detail, and compared to each other.
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Typology and development of Bohemian chateau architecture, 1620-1690
Bláha, Václav ; Horyna, Martin (advisor) ; Macek, Petr (referee)
The aim of the diploma thesis "Typology and Development of Bohemian Chateau Architecture, 1620-1690" is the definition and analysis of the principial functional and esthetical components of the chateau architecture, and also an attempt at their classification to wider context of early baroque Central European and European architectural development. The catalogue of 76 exquisited architectural objects is included.
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Lipoprotein-associated Phospholipase A2 in Geriatric Diabetic Patients
Fortunato, Joao ; Blaha, Vladimír (advisor) ; Nachtigal, Petr (referee) ; Soška, Vladimír (referee)
v anglickém jazyce Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an extracellular Ca2+- independent 45 KDa secreted enzyme formed by 441 amino acids. It circulates in plasma in the active form and is encoded in the PLA2G7 gene located on chromosome 6p12-21.1. Lp-PLA2 hydrolyzes several types of short-chain and oxidized phospholipids that harbor acyl groups at the second position of the glycerol backbone. It is mostly bound to low density liproprotein (LDL) particles and it is thought to play a role in the development of cardiovascular diseases (CVDs). Indeed, multiple studies propose that elevated mass concentration and/or activity of Lp-PLA2 is an independent risk factor for the development or recurrence of CVDs. We performed a cross-sectional analysis on 44 geriatric patients aged 79.6 ± 5.6 years that had undergone transcatheter aortic valve implantation (TAVI) or ballon valvuloplasty (BV) for the treatment of severe aortic stenosis. Lp-PLA2 mass concentration was already increased in elderly patients before TAVI or BV and significantly increased after the procedures. We found strong correlations with LDL concentration (LDL-C), total cholesterol and triglycerides. Baseline Lp-PLA2 mass concentration was increased in diabetic patients comparing to non-diabetic patients. We then discuss and...
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Non-existence as a new institution of Czech law
Bláha, Václav ; Hendrychová, Michaela (advisor) ; Šustek, Petr (referee)
Non-existence as a new institution of Czech law Abstract The aim of the thesis is to examine the institute of non-existence which is new in the Czech law. Therefore, the beginning of the thesis is arranged in order to make clear the chronological development of civil law in terms of wrongful conduct and/or wrongful legal act sanctions. Historically, the General Civil Code (ABGB) is of particular relevance. ABGB was an important civil code not only on our territory but also in Austria and other countries of the former Habsburg Monarchy. While the original text of this Code sanctioned wrongful legal acts by invalidity ("Ungültigkeit"), the 1916 amendment introduced another term into the Code, taken from the German Civil Code (BGB), and namely "Nichtigkeit". Although this term means "invalidity" as well, it was mistakenly translated into Czech by the word "nicotnost" (literally "nothingness" in English). In the thesis, the legal situation in the period from 1948 till 2014 is discussed briefly, mentioning in particular the Family Act which, commencing from 1998, included, in addition to the term "invalidity" (of marriage), also the term "non-existence" (of marriage) stating that no marriage is formed in these cases. The following part of the thesis deals with the applicable law. The problems of legal act, its...
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Tissue and soluble endoglin relation to the endothelial dysfunction and possible treatment
Blažíčková, Kateřina ; Nachtigal, Petr (advisor) ; Blaha, Vladimír (referee) ; Mičuda, Stanislav (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate: Msc. Katerina Blazickova Supervisor: Assoc. Prof. PharmDr. Petr Nachtigal, Ph.D. Title of Doctoral Thesis: Tissue and soluble endoglin relation to the endothelial dysfunction and possible treatment Atherosclerosis is a complex inflammatory disease and it represents a major source of morbidity and mortality in the world as a part of cardiovascular diseases. Endothelial dysfunction represents the first step in the development of atherosclerosis and it is characterized by disruption of endothelial homeostasis. Statins are drugs of choice in the treatment of atherosclerosis and they can decrease LDL cholesterol levels and positively affect levels of HDL cholesterol. Statins, however have a wide range of other effects, which are referred to non-lipid or pleotropic effects. The most important non-lipid effects of statins are lipid- independent modulation of endothelial function, antioxidant, anti-inflammatory, antithrombogenic and antiproliferative effects. The most widely used animal model for the study of atherosclerosis is the mouse model. Thanks to a high fat diet and genetic modification, we are able to modify lipid profile in mice and induce atherosclerotic changes even at...
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Eating habits of the nurses in shifts operation
Štěpinová, Pavla ; Kholová, Petra (advisor) ; Bláha, Vladimír (referee)
The aim of the bachelo's thesis was to get an overview of the eating habits of the nurses in shifts operation. In the practical part deals with topics of subjects healthy food, stress, nursing work of environment, burnout syndrome. The empirici part of the work was carried out of a in the form questionnaires surfy on based on an anonymous questionnaire.The questionnaire surfy was conducted at the Hradec Králové University hospital in standart types department and intencive care unit and nurses were approached. The results were processed using graphs and tables. And tables using the decriptive statistics method. The result is BMI findings in borderline and overweight values, focusing nurses on eating mostly Czech cuisines, and only half of their nurses able to consume 500g of vegetables and fruits a day. It was also found that nurses adhere to the drinking regime and drink mostly water. Health care gens are trying to care for their eating habits. Keys words Eating habits - nurses - stress - healthy food - nutrition
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The drinking regime among the paramedic staff
Štěpinová, Lenka ; Kholová, Petra (advisor) ; Bláha, Vladimír (referee)
v anglickém jazyce This bachelor thesis is focused the drinking regime among the paramedical staff on selected wards. The aim of this thesis was to analyse their drinking regime among on shift operation. The theoretical part contains general informatik about water, the water in the human body, drinking regime, the drinking regime rules, types liqiuds, minerals and complication drinking regime. Empirical part was approached by anonymous questionnaire. Approached by the paramedical staff on one - shift and three - shift operation. Research was carried out in faculty hospitál in Hradec králové. This data has been processed using descriptive statistics and for the sake of clarity have been presented using graphs and tables. The results showed that the health regime did not couly with the drinking regime, even though the new chat to do. Futher, research shows that the drink more table water and tap water than mineral water. Health care providers do not have coffee or tea drink regime. Alcohol drinks occasionally. As shown in the surfy, the shift operation affects the drinking regime. Keywords: drinking regime - the paramedic staff - water - dehydration
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Tissue and soluble endoglin relation to the endothelial dysfunction and possible treatment
Blažíčková, Kateřina ; Nachtigal, Petr (advisor) ; Blaha, Vladimír (referee) ; Mičuda, Stanislav (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate: Msc. Katerina Blazickova Supervisor: Assoc. Prof. PharmDr. Petr Nachtigal, Ph.D. Title of Doctoral Thesis: Tissue and soluble endoglin relation to the endothelial dysfunction and possible treatment Atherosclerosis is a complex inflammatory disease and it represents a major source of morbidity and mortality in the world as a part of cardiovascular diseases. Endothelial dysfunction represents the first step in the development of atherosclerosis and it is characterized by disruption of endothelial homeostasis. Statins are drugs of choice in the treatment of atherosclerosis and they can decrease LDL cholesterol levels and positively affect levels of HDL cholesterol. Statins, however have a wide range of other effects, which are referred to non-lipid or pleotropic effects. The most important non-lipid effects of statins are lipid- independent modulation of endothelial function, antioxidant, anti-inflammatory, antithrombogenic and antiproliferative effects. The most widely used animal model for the study of atherosclerosis is the mouse model. Thanks to a high fat diet and genetic modification, we are able to modify lipid profile in mice and induce atherosclerotic changes even at...
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