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Renal agenesis
Svobodová, Iveta ; Musil, Zdeněk (advisor) ; Merta, Miroslav (referee)
Renal agenesis is relatively common, genetically determined, disease. Genes which lead to its origin are still unconfirmed. Subject of this study was to perform molecular-genetic analyses of two genes, which are candidate for origin of renal agenesis in humans, genes coding tyrosine kinase receptor RET and neurotrophic factor GDNF. Mutation analysis of 20 exons of RET and 3 exons of GDNF in group of 20 patients with diagnosed unilateral renal agenesis has been done. Numeric changes were also investigated. The aim of this work was to identify potential mutation of RET and GDNF genes and contribute to their association with renal agenesis formation. No pathogenic mutation has been found in the group of patients, only three known single-point polymorphisms in RET gene have been detected. Polymorphism rs1800860 (GCG-GCA, Ala-Ala 432) is situated in exon 7 and has been found in 9 of total 20 patients, thereof in two cases in homozygous state. Polymorphism rs1800861 (CTT-CTG, Leu-Leu 769) is located in exon 13 and has been identified in 3 of 20 patients, thereof one patient was homozygote for minority allele G. Polymorphism rs1800863 (TCC-TCG; Ser- Ser) in 15. exon has been found in 5 patients, at any time in heterozygous state. All cases are about common polymorphisms with frequency of minority allele...
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Evaluation training loading and performance grow up for five years period of Tereza Huříková and Michal Talavašek in mountain bike discipline of cross country
Pálka, Tomáš ; Heller, Jan (advisor) ; Vomáčko, Ladislav (referee)
Title: Evaluation training loading and performance grow up for five years period of Tereza Hu íková and Michal Talava ek in mountain bike discipline of cross country Abstract: I evaluating and analysing training loading and performance grow up for five years period in discipline of cross country in my theses. Mountain bike, especially discipline of cross country is very exacting and endurance sport, which takes oneself a lot of specifice in sports, technic and psychology preparation and this sport puts a giant claims of subjects voluntary characteristics. Training loading induces changes in organism, which it shows to grow up of specialization performance. I chose two of very talented subjects, the racers of mountain bike, which young, but reached of admirable accomplishment in there sport. Keywords: mountain biking, training, performance Objectives: The aim of this theses is kazuistic study (intensive and deep study the presentive human and his situations and problems). I analysed, training loading and performance grow up with consequently evaluating by Tereza |Hu íková and Michal Talava ek, pursuant of interview, trainings date books and laboratory tests. Methods: This theses is qualitative research, when I sought out and analyzing any informations this problem, and there explication. Data acquisition and...
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Crisis and personal growth. Possibilities and metaphors of crisis
Veselá, Ivana ; Šípek, Jiří (referee) ; Bahbouh, Radvan (advisor)
Each person has an experience with crisis, it is a natural part of human life. A crisis has an inner potential in the form of a challenge and it brings a new possibility for people in percieving reality and themselves. In this thesis I focuse on possibilities which open for those people who seek a professional advice. I suppose that crisis is a part of the process of personal growth. Therefore the main theoretical chapters refere to these two themes. First I define what a crisis is including it's course and various types. Than I place crisis into the context of difficult life situations including coping strategies. Personal growth is defined in the view of development and change. Both are focused on the process. The goal of personal growth is described in a sub-chapture on optimal personality. The following chapter is on positive psychology which pays attention to the quality of life. I suppose that the most important concepts of these fields of study are Rotter's Locus of control and Seligman's learned helplessness. Out of psychoterapeutical schools I have chosen existencial-humanistic tradition which corresponds to my research question the most. I put attention to the founders of main schools - V. E. Frankl's Logotherapy, A. Maslow's Humanistic psycholgy, C.R. Rogers's Client-centred therapy and F....
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Drop-out of seminarians
Krampl, Petr ; Eliáš, Vojtěch (advisor) ; Mrňávek, Tomáš (referee)
Author: KRAMPL Petr Corporation: Catholic Theology Faculty of Charles University The thesis primarily deals with the topic of preparation for priesthood according to the literature and Church documents published after The Second Vatican Council. The phenomenon of leaving seminary is being analyzed on the basis of interviews with drop-out seminarians. Based on Grounded theory, a qualitative research method, the thesis characterizes basic processes the seminarians go through both before and after leaving the seminary and denominates areas of their possible inner conflicts. Keywords: seminarians, vocation, training course, drop-out, disillusion, reintegration, Number of characters: 110364, Number of pages: 62, Number of appendices: 4, Number of literature: 16
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Safety problems of modern nuclear reactors
Kukla, Jaroslav ; Matějíček, Luboš (referee) ; Přibil, Rudolf (advisor)
Jaroslav Kukla Otázky bezpe nosti moderních jaderných reaktor Bakalá ská práce Abstract: This study is concerned with safety factors of nuclear reactors. It summarizes history of nuclear reactors development and analyses causes of some serious accidents, which occurred in the past. It describes physical characteristics of radioactive radiation and mentions a basic survey of quantities and units. Then it describes the influence of radioactive emission on man and other living organisms. It also defines some reactor components and focuses on general security principles, which are further developed. It shortly explains the methods of evaluation of safety factors of nuclear reactors and a role of nuclear supervision. It puts nuclear reactors into several generations and every type of reactor is described as for technical and safety aspects, respectively. It refers to contemporary trends in development of nuclear reactors and in development of their safety.
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Phototoxicity and influence of the human health
Záborcová, Tamara ; Vytlačilová, Jitka (advisor) ; Jahodář, Luděk (referee)
When the UV radiation strikes on the organism, it interacts with bioactive molecules, which leads to their changes with various consequences including mutations, cancerogenesis, photosensitivity and other disorders. This writing deals with UV radiation negative effects on human, diseases, which are induced by it, its utilization in medicine and also with photoprotection and possible modulation of damage induced by this radiation.
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The disappointment of the Western intellectual in the twentieth century (in Saul Bellow's novels Mr. Sammler's Planet and Herzog)
Slováčková, Hana ; Roraback, Erik Sherman (referee) ; Ulmanová, Hana (advisor)
Saul Bellow's main characters are frequently persons who convey their experience with reality in the contemporary Western society. The concrete phenomena - their individual experiences fold up into a more conclusive reflection and lead to the comprehension of reality on a general level. And it is disappointment that best characterizes the resulting knowledge. The novels I selected for the thorough analysis, Mr.Sammler's Planet and Herzog, both depict and encounter of man with reality. The reflection of this encounter is presented by scholarly men, Mr. Sammler and Moses E. Herzog. Despite the fact that they are fictitious characters, their knowledge of Western thinkers makes them 'real' intellectual critics of the contemporary time. They connect through their theoretical scholarship and their personal lives, observations and experiences. The outcome is an account of the state of the contemporary Western society in the light of a broader understanding of its development. The course of that development or transformation can be analyzed with the help of works of influential Western thinkers for their reasoning always arises from the conditions of their present time. Their works containing novel concepts have impact on the future development but also inevitably reflect the past development. This is the reason...
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Quantitative and qualitative indicators of pollenproduction from crop of red fescue (Festuca Rubra L.) in depending on agricultural technology
RATAJOVÁ, Alena
V diserta.ni praci se pojednava o problematice vlivu r.zne urovn. vy.ivy travnich porost. dusikem na zm.ny chemicke skladby pyloveho zrna a na zm.ny jeho alergenicity. V sou.asne dob. otazka p.stovani travnich porost. velice aktualni. Travnich porost. se p.stuje stale vice a vice z r.znych d.vod.. Nap.. v poslednich letech siln. poklesl stav mle.neho skotu a naopak siln. narostl vyznam chovu masnych plemen, ktera jsou vazana na pastevni programy. Dota.ni tituly sm..ujici do teto oblasti vyu.iti zem.d.lske p.dy jsou ekonomicky velmi zajimave. Navic, krom. b..nych ploch, jsou tedy systematicky zakladany semena.ske porosty trav pro vyrobu certifikovanych osiv (ve v.t.im rozsahu), ktera se pou.ivaji nasledn. pro zasev pastevnich a lu.nich porost.. Sou.asne celosv.tove zem.d.lstvi, zejmena v marginalnich oblastech (LFA), hleda nove a alternativni zp.soby vyu.iti zem.d.lske produkce. Jednim z nich je i cilena produkce biomasy trav. Tato je vyznamnou sou.asti celkoveho potencialu biomasy, jako obnovitelneho p.irodniho zdroje vyu.itelneho pro energeticke u.ely v podminkach nap.. i .eske republiky. Energeticke vyu.iti trav je novym sm.rem jejich vyu.iti v pr.myslu a vytva.i nove mo.nosti pro vyzkum v teto oblasti a praktickou realizaci. V sou.asnosti je vyzkum energetickych trav zam..en na realizaci spalovani travni biomasy v technickych za.izenich a vyu.iti trav pro produkci bioplynu. Soudobym trendem je nejen vyzkum ekonomickeho p.inosu, ale i vyzkum dopadu novych trend. na .ivotni prost.edi, krajinu a obyvatelstvo. B.hem poslednich dvou desetileti stoupl vyskyt alergii v n.kterych civilizovanych statech na 30 . 40% populace. Ji. ka.dy .tvrty a. paty .lov.k trpi alergii. Diserta.ni prace je pilotnim projektem, ktery propojuje zem.d.lstvi se sou.asnymi poznatky farmaceutickeho pr.myslu, chape pyl jako sekundarni - finalni produkt rostliny a hleda odpov.di na otazky dopadu r.zne urovn. vy.ivy travnich porost. na lidske zdravi.
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