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Analysis of drug administration by nurses in health facility XV.
Chudovská, Denisa ; Malý, Josef (advisor) ; Dvořáčková, Simona (referee)
Analysis of drug administration by nurses in health facility XV. Author: Denisa Chudovská Tutor: doc. PharmDr. Josef Malý. Ph.D. Consultant: Mgr. Ondřej Tesař Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: The role of nurses is key not only in the occurrence of medication errors, but also in their prevention. The aim of the thesis was to analyze the administration of medications by nurses to patients hospitalized in three departments within a healthcare facility and to compare the results with the first year of monitoring in the given hospital. Methods: This is an observational-interventional study. The data collection method was passive observation. The study included patients in surgical, internal medicine, and post-care departments within one of the four hospitals in the Czech Republic. Data collection took place over three consecutive days. The collected data encompassed information: about the patient, the nurse and medication name, strength, preparation, administration, usage verification. The analysis of obtained data was performed using a Summary of Product Characteristics and relevant information sources available at the Pharmaceutical Faculty of Charles University in Hradec Králové. To assess the impact of...
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Analysis of the possibilities of influencing antibiotic prophylaxis on the basis of inflammatory markers II
Strnadová, Gabriela ; Malý, Josef (advisor) ; Šorf, Aleš (referee)
Analysis of the possibilities of influencing antibiotic prophylaxis on the basis of inflammatory markers II Author: Gabriela Strnadová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Petr Domecký Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Periprosthetic joint infections are considered as the biggest complication of the implementation of the total arthroplasty which may be reduced by the observation of inflammatory and nutritional markers. The aim of this thesis is to analyse the possibilities of influencing the antibiotic prophylaxis (AP) on the basis of those markers observed on patients that underwent the total hip arthroplasty (THA) and the total knee arthroplasty (TKA). Methods: Data was collected from a prospective study which began in March 2020 at the Department of Orthopedics at the University Hospital Hradec Králové. There were 118 patients from May 2021 to June 2022 older than 18 years with THA and TKA included in the analysis. The analysed data were sourced from the paper and electronic forms of medical documentary materials of those patients. Patients'personal and medical details (including the information about the operation, the thromboprophylaxis (TP), AP, and the results of physical and...
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Analysis of patient adherence to treatment by DOAC II
Janáčková, Natália ; Malý, Josef (advisor) ; Hendrychová, Tereza (referee)
6 Abstract Analysis of patient adherence to treatment by DOAC II Author: Natália Janáčková Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Simona Dvořáčková, Ph.D., Mgr. Eliška Mašková Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aim: Dosing interval may be an important factor influencing adherence to direct oral anticoagulant (DOAC) therapy. In terms of adherence, a once-daily regimen appears to be a better alternative. However, there may be a higher risk of treatment failure if the dose is missed. The aim of the practical part of the thesis was to analyse patients' attitudes and experiences with DOACs, complemented by data from medical records, with a focus on aspects related to DOAC dosing. Methods: Data collection for this prospective study was carried out from 2020 to 2022 at the Internal Cardiology Outpatient Clinic of the University Hospital in Brno. Patients aged ≥ 18 years on DOAC treatment with indicated atrial fibrillation (FS) were approached to participate in the study. Each patient underwent a structured interview with a trained pharmacist on the day of study entry and again after 3 and 6 months. Two validated and three supplementary questionnaires were used in the interview. Patients' attitudes, experiences...
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Analysis of drug administration by nurses in health facility VIII
Vaclaviková, Iveta ; Malý, Josef (advisor) ; Šorf, Aleš (referee)
Author: Iveta Vaclaviková Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Ondřej Tesař Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Medication errors contribute significantly to the occurrence of adverse events that can impact patient health. The aim of this thesis was to analyze the administration of drugs to patients hospitalized by nurses in one of four studied health facilities in the South Bohemia region in the surgical, internal medicine and aftercare wards. Methods: This diploma thesis is part of an observational-interventional study, in years 2020- 2023. Observations took place in internal medicine, surgery and aftercare wards. Collection of data was held from 23th May to 26th May 2022 by a multidisciplinary team made up of a pharmacist and a nurse by direct observation method. These following data were collected: information about pacient (e.g., gender, age, and any medications taken), information about the nurse by whom the medications were administered (e.g., age, years of experience, highest educational attainment), and information recorded during the actual administration of the medications (e.g. nurse compliance with hygiene requirements; patient identification; checking originality of the drug; whether the...
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Analysis of drug administration by nurses in health facility VII
Polášová, Barbora ; Malý, Josef (advisor) ; Kolmanová, Eliška (referee)
Analysis of drug administration by nurses in health facility VII Author: Barbora Polášová Tutor: doc. PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Medication errors can cause a great risk in administration of drugs to health of patients. The aim of this thesis was to analyze the administration of drugs by nurses to patients hospitalized in three different wards in a medical facility in the South Bohemian region. Mathods: This thesis is a part of an observational-interventional study, ongoing in 2020-2023. Collection of data was held in one of South Bohemian hospitals in the surgery, internal medicine and aftercare wards between 17th May and 19th May. Data were collected by a direct observation method by a trained multidisciplinary team consisting of pharmacists and nurses. The observed parameters were: information about patient (e.g. gender, age and used medications), information about nurse (e.g. gender, age, length of practice) and drug administration's data (e.g. hygiene, patient identification, correct medication, right dose and strength, right patient, correct time, way of drug's manipulation, used drink for wash down, time interval from food). All collected data were anonymized,...
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Measuring adherence in patients with oral targeted therapy in chronic lymphocytic leukaemia
Hanusová, Barbora ; Malý, Josef (advisor) ; Kolmanová, Eliška (referee)
Measuring adherence in patients with oral targeted therapy in chronic lymphocytic leukaemia Author: Barbora Hanusová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Petra Rozsívalová Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Chronic lymphocytic leukaemia (CLL) is a hematological disorder characterized by clonal proliferation of mature B-cells. New oral targeted drugs have been used in clinical practice to treat CLL. The aim of this thesis was to measure adherence to oral targeted drugs, analyze pharmacotherapy and identify drug-related problems (DRP) and their management. Methods: The cross-sectional pilot study ran from September 2022 to March 2023 in University Hospital Hradec Králové. Patients ≥ 18 years old, with CLL diagnosis treated with ibrutinib, acalabrutinib or venetoclax were included. Medical data and pharmacotherapy were obtained using electronic medical records and patients' medication records. Guided interviews were performed to measure patients' adherence to oral targeted oncolytics using Czech version of The Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS-CZ) and determine their opinions about medicine using Czech translation of The Beliefs about Medicines...
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Analysis of drug administration by nurses in health facility XII
Gröszlová, Anna ; Doseděl, Martin (advisor) ; Malý, Josef (referee)
ANALYSIS OF DRUG ADMINISTRATION BY NURSES IN HEALTH FACILITY XII Author: Anna Gröszlová Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Charles University, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy Introduction: Medication administration in healthcare facilities significantly affects patient's safety. Observing and analyzing this process provide information about medication administration errors and the factors influencing them. As a result of observational findings, we can create interventions to improve the administration process. Aim: The aim of this work was to describe and analyze medication administration errors in a healthcare facility. Methods: The direct observation method was used for observation. Data collection took place in three departments (surgery, neurology, follow-up care) in 2021 and 2022. In both years, collection took place in each department on 3 consecutive days. Morning, midday and evening medication administration was monitored. An electronic database was used for recording. Data evaluation was done in Microsoft Excel and data from 2021 and 2022 were analyzed together. Nurse's work practices and medication errors were evaluated. Results: In total, 1160 drug administrations to 114 patients were observed. The largest number of...
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Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019
Suchopárová, Lenka ; Malý, Josef (advisor) ; Kolář, Jozef (referee)
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019 Author: Lenka Suchopárová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Petr Domecký Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles university Introduction and aims: Antibiotics (ATB) are substances with a bacteriostatic or bactericidal effect. Treatment with ATB carries a risk of side effects, drug interactions and risk of resistance occurence. The reason for monitoring the consumption of ATB is not only the apparent coherence between their consumption and the increase of resistance, but also the economic side of bacterial infections treatment. The aim of this study was to analyze the consumption of ATB for systematic administration in the Czech Republic (CR) in 2005-2019. Methods: The analysis of the consumption of ATB was performed as a retrospective analysis of data from the database of the State Institute of Drug Control in the period from 1. 1. 2005 to 31. 12. 2019. Anatomical-therapeutic-chemical classification based on defined daily doses (DDD) of individual drugs was used for the analysis. The consumption of ATB was calculated as DDD per thousand inhabitants per day (TID). The data on the number of residents was acquired from the...
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Analysis of pharmacotherapy in patients in the hospice
Sládek, Jakub ; Malý, Josef (advisor) ; Zimčíková, Eva (referee)
Analysis of pharmacoterapy hospice care patients Author: Jakub Sládek Tutor: doc. PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and purpose: The therapy of hospice care patients is accompanied by many changes and pitfalls that need to be balanced when choosing appropriate therapy. In the teoretic part we can find available information about paliative therapy of hospice care patients, with emhasis on pain therapy. The aim of this thesis is the analysis of pharmacotherapy hospice care patients. Methods: The data were collected in a hospice from September 2019 to November 2019. The farmacotherapy was revised every first day of the month. Informations from personal, drug, family and occupational social history of patients were noted into an electronic database and, after revision, were classified and evaluated by frequency analysis. In four randomly selected patients was described the management of drug-related problems (DRP). Results: In total we noted medical therapy in 40 patients, women were 75 % of this number. Average patient's age was 72.4 years for men and 74.6 for women. Patients most often used drugs from group N (drugs of the nervous system) according to the ATC classification. We indentified 115...
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Analysis of drug administration by nurses in health facility III
Novosadová, Aneta ; Malý, Josef (advisor) ; Šorf, Aleš (referee)
1 Abstract Analysis of drug administration by nurses in a health facility III Author: Aneta Novosadová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Ondřej Tesař Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: The drug administration by nurses is one of the most important part of a nursing care performed on daily basis. The goal of this master's thesis was to analyze the drug administration by nurses to the patients hospitalized in the internal, surgical or aftercare wards in one of four health facilities in the South Bohemian region with an emphasis on medication errors and their prevention. Methods: This is a part of an extensive observational and intervention study, which is conducted between years 2020-2023. The thesis demonstrates the data acquired by a direct observation of drug administration to the hospitalized patients from 19th to 25th July 2021. The data were collected by teams composed by a pharmacist and a nurse. The collected data were as follow: patients' personal data (e.g., age, gender, list of all drugs used by patient), data about the nurse who administered drugs (age, gender, length of working experience), data of the drug administration (the way of identification of the patient; the nurse's hygiene...
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