Název:
Antimicrobial peptides isolated from the venom of wild bee Panurgus calcaratus
Autoři:
Čujová, Sabína ; Monincová, Lenka ; Slaninová, Jiřina ; Bednárová, Lucie ; Čeřovský, Václav Typ dokumentu: Příspěvky z konference Konference/Akce: Biologically Active Peptides /12./, Praha (CZ), 2011-04-27 / 2011-04-29
Rok:
2011
Jazyk:
eng
Abstrakt: Three novel peptides designated as PNG-1, PNG-K and PNG-R were isolated from the venom of the solitary bee Panurgus calcaratus. They exhibited antimicrobial activity against Grampositive and -negative bacteria and fungi. In this work we focused on the characterization of PNG-R which is unique 25 amino acid residues and two disulfide bridges containing peptide. The secondary structure of PNG-R was studied by circular dichroism spectroscopy measured in water and in the presence of trifluoroethanol or sodium dodecyl sulfate.
Klíčová slova:
alpha-Helical structures; antimicrobial peptides; bee venom; disulfide bridges; Panurgus calcaratus Číslo projektu: CEZ:AV0Z40550506 (CEP), GA203/08/0536 (CEP) Poskytovatel projektu: GA ČR Zdrojový dokument: Biologically Active Peptides. 12th Conference, ISBN 978-80-86241-44-9
Instituce: Ústav organické chemie a biochemie AV ČR
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Informace o dostupnosti dokumentu:
Dokument je dostupný v příslušném ústavu Akademie věd ČR. Původní záznam: http://hdl.handle.net/11104/0204309