Original title:
Antimicrobial peptides isolated from the venom of wild bee Panurgus calcaratus
Authors:
Čujová, Sabína ; Monincová, Lenka ; Slaninová, Jiřina ; Bednárová, Lucie ; Čeřovský, Václav Document type: Papers Conference/Event: Biologically Active Peptides /12./, Praha (CZ), 2011-04-27 / 2011-04-29
Year:
2011
Language:
eng Abstract:
Three novel peptides designated as PNG-1, PNG-K and PNG-R were isolated from the venom of the solitary bee Panurgus calcaratus. They exhibited antimicrobial activity against Grampositive and -negative bacteria and fungi. In this work we focused on the characterization of PNG-R which is unique 25 amino acid residues and two disulfide bridges containing peptide. The secondary structure of PNG-R was studied by circular dichroism spectroscopy measured in water and in the presence of trifluoroethanol or sodium dodecyl sulfate.
Keywords:
alpha-Helical structures; antimicrobial peptides; bee venom; disulfide bridges; Panurgus calcaratus Project no.: CEZ:AV0Z40550506 (CEP), GA203/08/0536 (CEP) Funding provider: GA ČR Host item entry: Biologically Active Peptides. 12th Conference, ISBN 978-80-86241-44-9
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0204309