Original title:
Analysis of antimicrobial peptides by capillary electrophoresis
Authors:
Ehala, Sille ; Niederhafner, Petr ; Čeřovský, Václav ; Řezanka, P. ; Sýkora, D. ; Král, V. ; Kašička, Václav Document type: Papers Conference/Event: Biologically Active Peptides /12./, Praha (CZ), 2011-04-27 / 2011-04-29
Year:
2011
Language:
eng Abstract:
Capillary electrophoresis was used for the purity degree determination of new antimicrobial peptides: octadecapeptide melectin and tetradecapeptide mastoparan PDD-B, and their synthetic analogues. Besides, four semiempirical models correlating electrophoretic mobilities of these peptides with their charge and size (relative molecular mass) were applied to predict their probable structures in solution. Additionally, capillaries coated with gold nanoparticles were employed for the separation of mixtures of antimicrobial peptides.
Keywords:
antimicrobial peptides; capillary electrophoresis; gold nanoparticles Project no.: CEZ:AV0Z40550506 (CEP), GA203/09/0675 (CEP), GA203/08/1428 (CEP) Funding provider: GA ČR, GA ČR Host item entry: Biologically Active Peptides. 12th Conference, ISBN 978-80-86241-44-9
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0204285