Název:
Optimization of Continuous Synthesis of Trazodone
Autoři:
Jaklová, Natalie Typ dokumentu: Příspěvky z konference Konference/Akce: Bažant Postgraduate Conference 2025, Prague (CZ), 20250617
Rok:
2025
Jazyk:
eng
Abstrakt: This study explores the feasibility of synthesizing Trazodone in continuous mode using a tubular reactor and investigates the impact of ultrasound\non phase-transfer catalyzed (PTC) N-alkylation. One of the suitable approaches for a continuous system was solid-liquid arrangement described\nby Jaśkowska et. al, while synthesis is carried out in two steps with ultrasound assistance. The hypothesis for the reaction intensification with solid-liquid arrangement is that sonication accelerates transport at the solid-liquid interface and thus intensifies the reaction. Zdrojový dokument: Proceedings of Abstracts, ISBN 978-80-86186-35-1
Instituce: Ústav chemických procesů AV ČR
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Informace o dostupnosti dokumentu:
Dokument je dostupný v repozitáři Akademie věd. Původní záznam: https://hdl.handle.net/11104/0367278