Original title: Optimization of Continuous Synthesis of Trazodone
Authors: Jaklová, Natalie
Document type: Papers
Conference/Event: Bažant Postgraduate Conference 2025, Prague (CZ), 20250617
Year: 2025
Language: eng
Abstract: This study explores the feasibility of synthesizing Trazodone in continuous mode using a tubular reactor and investigates the impact of ultrasound\non phase-transfer catalyzed (PTC) N-alkylation. One of the suitable approaches for a continuous system was solid-liquid arrangement described\nby Jaśkowska et. al, while synthesis is carried out in two steps with ultrasound assistance. The hypothesis for the reaction intensification with solid-liquid arrangement is that sonication accelerates transport at the solid-liquid interface and thus intensifies the reaction.
Host item entry: Proceedings of Abstracts, ISBN 978-80-86186-35-1

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0367278

Permalink: http://www.nusl.cz/ntk/nusl-680519


The record appears in these collections:
Research > Institutes ASCR > Institute of Chemical Process Fundamentals
Conference materials > Papers