Original title: Enzymatic synthesis of ester prodrugs of DHPA and related compounds by lipases
Authors: Blažek, Jiří ; Kaiser, M. M. ; Zarevúcka, Marie ; Králová, B. ; Krečmerová, Marcela
Document type: Papers
Conference/Event: Chemistry of Nucleic Acid Components /15./, Český Krumlov (CZ), 2011-06-05 / 2011-06-10
Year: 2011
Language: eng
Abstract: An enzymatic method was used for esterification of DHPA and related compounds with vinyl esters and catalyzed by different lipases in non-aqueous media (DMF). Esters of DHPA and other compounds could be synthesized and purified in satisfactory yields.
Keywords: DHPA; ester prodrugs; lipases; transesterification; vinyl esters
Project no.: CEZ:AV0Z40550506 (CEP), 1M0508 (CEP)
Funding provider: GA MŠk
Host item entry: Chemistry of Nucleic Acid Components. 15th Symposium, ISBN 978-80-86241-37-1

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0198529

Permalink: http://www.nusl.cz/ntk/nusl-55786


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers