Original title:
Synthesis and biological properties of the 2’-trifluoromethyl analogues of tenofovir
Authors:
Jansa, Petr ; Kolman, Viktor ; Janeba, Zlatko Document type: Papers Conference/Event: Chemistry of Nucleic Acid Components /15./, Český Krumlov (CZ), 2011-06-05 / 2011-06-10
Year:
2011
Language:
eng Abstract:
A series of acyclic nucleoside phosphonates substituted at the aliphatic part of the molecule by the trifluoromethyl group was prepared but none of the compounds exhibits any anti-HIV or anti-HCV activities.
Keywords:
acyclic nucleoside phosphonates; ANPs; trifluoromethyl group Project no.: CEZ:AV0Z40550506 (CEP), 1M0508 (CEP) Funding provider: GA MŠk Host item entry: Chemistry of Nucleic Acid Components. 15th Symposium, ISBN 978-80-86241-37-1
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0198497