Original title: Synthesis and biological properties of the 2’-trifluoromethyl analogues of tenofovir
Authors: Jansa, Petr ; Kolman, Viktor ; Janeba, Zlatko
Document type: Papers
Conference/Event: Chemistry of Nucleic Acid Components /15./, Český Krumlov (CZ), 2011-06-05 / 2011-06-10
Year: 2011
Language: eng
Abstract: A series of acyclic nucleoside phosphonates substituted at the aliphatic part of the molecule by the trifluoromethyl group was prepared but none of the compounds exhibits any anti-HIV or anti-HCV activities.
Keywords: acyclic nucleoside phosphonates; ANPs; trifluoromethyl group
Project no.: CEZ:AV0Z40550506 (CEP), 1M0508 (CEP)
Funding provider: GA MŠk
Host item entry: Chemistry of Nucleic Acid Components. 15th Symposium, ISBN 978-80-86241-37-1

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0198497

Permalink: http://www.nusl.cz/ntk/nusl-55777


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers