Název: Katepsiny B ptačí schistosomy Trichobilharzia regenti
Překlad názvu: Cathepsins B of the bird schistosome, Trichobilharzia regenti
Autoři: Dolečková, Kateřina ; Horák, Petr (vedoucí práce) ; Grevelding, Christoph (oponent) ; Horn, Martin (oponent)
Typ dokumentu: Disertační práce
Rok: 2010
Jazyk: eng
Abstrakt: 1. Overview Schistosomes have achieved first position among parasitic helminths, because some of them are the etiological agents of a serious human parasitic disease, schistosomiasis, which affects over 200 million people in tropical and subtropical countries (WHO, 2001). Other schistosomatids, such as the bird flukes of the genus Trichobilharzia, have also implications for human health. Although they can mature only in specific hosts (birds), their invasive larvae - cercariae - are able to penetrate also human skin due to chemical signals similar to those present on bird skin (Haas and van de Roemer 1998). Repeated infections result in an inflammatory reaction of the skin called cercarial dermatitis. Due to the increasing number of outbreaks all around the world, cercarial dermatitis is cons disease (Kolářová 2007idered as re-emerging ; Larsen et al. 2004). Among schistosomes, Trichobilharzia regenti is the only species described so far having a unique migration route within vertebrate hosts: after penetration of the skin, the invasive larvae enter peripheral nerves and continue via the spinal cord and central nervous system to the nasal cavity of birds, causing neuromotor disorders or paralyses of birds and even experimental mammals (Hrádková...
Klíčová slova: katepsin; parazit; peptidáza; schistosomy; Trematoda; cathepsin; parasite; peptidase; schistosomes; Trematoda

Instituce: Fakulty UK (VŠKP) (web)
Informace o dostupnosti dokumentu: Dostupné v digitálním repozitáři UK.
Původní záznam: http://hdl.handle.net/20.500.11956/26215

Trvalý odkaz NUŠL: http://www.nusl.cz/ntk/nusl-465053


Záznam je zařazen do těchto sbírek:
Školství > Veřejné vysoké školy > Univerzita Karlova > Fakulty UK (VŠKP)
Vysokoškolské kvalifikační práce > Disertační práce