Original title: Monitoring of enzymatic enantioselective acetylation of gem-difluorinated alcohols by capillary electrophoresis
Authors: Šolínová, Veronika ; Pomeisl, Karel ; Lamatová, Nikola ; Pohl, Radek ; Brabcová, Jana ; Krečmerová, Marcela ; Kašička, Václav
Document type: Papers
Conference/Event: Advances in Chromatography and Electrophoresis & Chiranal 2018, Olomouc (CZ), 20180129
Year: 2018
Language: eng
Abstract: A new fast and highly efficient capillary electrophoretic (CE) method has been developed for chiral analysis of non-charged gem-difluorinated alcohol (3-(benzyloxy)-1,1-difluoro-propan-2-ol) using sulfobutylether-β-CD as chiral selector. The method was applied for monitoring of enzymatic (lipase mediated) enantioselective acetylation of the above alcohol and for determination of enantiomeric purity of both substrates and products of the enzymatic reaction.
Keywords: capillary electrophoresis; difluorinated alcohols; enantioselective acetylation
Project no.: GA15-01948S (CEP), GA17-10832S (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: Advances in Chromatography and Electrophoresis & Chiranal 2018

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0286867

Permalink: http://www.nusl.cz/ntk/nusl-386560


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers