Original title:
The synthesis of monomers for prolinol-based oligonucleotides
Translated title:
Syntéza monomerů pro prolinolové oligonukleotidy
Authors:
Vaněk, Václav ; Buděšínský, Miloš ; Rosenberg, Ivan Document type: Papers Conference/Event: Chemistry of Nucleic Acid Components /13./, Špindlerův Mlýn (CZ), 2005-09-03 / 2005-09-09
Year:
2005
Language:
eng Abstract:
[eng][cze] A series of prolinol-based modified nucleotide monomers with phosphonomethyl or phosphonoformyl group attached to the pyrrolidine nitrogen was prepared; the monomers will be used for solid phase synthesis of oligonucleotide analogues.Byla připravena série monomerů modifikovaných nukleotidů odvozených od prolinolu s fosfonomethylovou nebo fosfonoformylovou skupinou vázanou na dusík pyrrolidinového kruhu, které budou použity k syntéze analog oligonukleotidů na pevné fázi.
Keywords:
hydroxyprolinol; oligonucleotides; phosphonates Project no.: CEZ:AV0Z40550506 (CEP), IAA4055101 (CEP), GA203/05/0827 (CEP) Funding provider: GA AV ČR, GA ČR Host item entry: Chemistry of Nucleic Acid Components, ISBN 80-86241-25-4
Institution: Institute of Organic Chemistry and Biochemistry AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0111643