Original title: Investigation of acid-based properties of mono- and diaza[5]helicenes by non-aqueous capillary electrophoresis and quantum chemical calculations
Authors: Šolínová, Veronika ; Štěpánová, Sille ; Jančařík, Andrej ; Klívar, Jiří ; Šámal, Michal ; Stará, Irena G. ; Vacek Chocholoušová, Jana ; Vacek, Jaroslav ; Starý, Ivo ; Kašička, Václav
Document type: Papers
Conference/Event: Advances in Chromatography and Electrophoresis & Chiranal 2016, Olomouc (CZ), 20160606
Year: 2016
Language: eng
Abstract: Non-aqueous capillary electrophoresis (NACE) using methanol (MeOH) as a solvent of the background electrolytes was used to determine the thermodynamic acidity (ionization) constants (pKa) of a series of monoaza[5]helicenes and diaza[5]helicenes protonated to the first degree in MeOH and water. Depending on the number and position of the nitrogen atoms in their molecules, the analyzed aza[5]helicenes were found to be weak to moderate bases with methanolic pKa,MeOH in the range 3.90-8.75 and with aqueous pKa,H2O in the range 3.53-8.28.
Keywords: acidity constant; azahelicenes; capillary electrophoresis
Project no.: GA15-01948S (CEP)
Funding provider: GA ČR
Host item entry: Advances in Chromatography and Electrophoresis & Chiranal 2016, ISBN 978-80-244-4961-6

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0267206

Permalink: http://www.nusl.cz/ntk/nusl-262649


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers