Original title: Capillary electrophoresis applied to chiral analysis of helquats and characterization of their intermediates and interconversion barriers using randomly and single isomer sulfated cyclodextrins as stereoselectors
Authors: Kašička, Václav ; Koval, Dušan ; Sázelová, Petra ; Severa, Lukáš ; Vávra, Jan ; Adriaenssens, Louis ; Sonawane, Manoj R. ; Teplý, Filip
Document type: Papers
Conference/Event: Advances in Chromatography and Electrophoresis & Chiranal 2014, Olomouc (CZ), 2014-02-10 / 2014-02-14
Year: 2014
Language: eng
Abstract: Capillary electrophoresis in acidic sodium phosphate background electrolyte, pH 2.4, with randomly sulfated alfa-, beta- and gamma-cyclodextrins as chiral selectors was applied to fast, high-resolution separation of enantiomers of a series of 35 helquats, a new class of N-heteroaromatic dicationic helicene-like species. The developed methodology was employed for evaluation of preparative enantioresolution procedures of helquats, for monitoring their racemization and for determination of interconversion barrier of helquat enantiomers.
Keywords: capillary electrophoresis; chiral analysis; helquats
Project no.: GAP206/12/0453 (CEP), GA13-17224S (CEP), GA13-32974S (CEP)
Funding provider: GA ČR, GA ČR, GA ČR
Host item entry: Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Chemica 51S, ISBN 978-80-244-3950-1, ISSN 0232-0061

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0235362

Permalink: http://www.nusl.cz/ntk/nusl-187441


The record appears in these collections:
Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers