Original title: Design and Synthesis of Helicene like Molecules
Authors: Bernard, Martin ; Sýkora, Jan ; Storch, Jan
Document type: Papers
Conference/Event: Symposium on Catalysis /43./, Praha (CZ), 2011-11-07 / 2011-11-08
Year: 2011
Language: eng
Abstract: Azahelicenes are unique inherently chiral three-dimensional aromatic compounds with high potential in homogenous assymetric catalysis. Their synthesis has many drawbacks and cannot be done in multigram scale so far. Recently, we have developed a route to new type of helicene-like molecules II. Multigram-scale synthesis of model compound where two benzene rings in [6]helicene skeleton are replaced by cyclopentadiene rings was accomplished in three steps. Such molecules have helical structure similar to helicenes, however, lower racemization barrier. Appropriately modified aza-analogues could be suitable catalysts for asymmetric reactions. Therefore, our synthetic approach leading to these compounds will be discussed.
Keywords: aromatics compounds; catalysis; synthesis
Project no.: CEZ:AV0Z40720504 (CEP), GAP207/10/1124 (CEP), TA01010646 (CEP)
Funding provider: GA ČR, GA TA ČR
Host item entry: Program Book of Abstracts, ISBN 978-80-87351-15-4
Rights: This work is protected under the Copyright Act No. 121/2000 Coll.

Institution: Institute of Chemical Process Fundamentals AS ČR (web)
Original record: http://hdl.handle.net/11104/0208796

Permalink: http://www.nusl.cz/ntk/nusl-111538


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