National Repository of Grey Literature 8 records found  Search took 0.01 seconds. 
Managerial Competencies in Small Enterprises
Novák, Petr ; Szarková, Miroslava (referee) ; Mohelská, Hana (referee) ; Tomšík, Pavel (referee) ; Putnová, Anna (advisor)
The dissertation thesis dealt with the managerial competencies in the small manufacturing enterprises in the Czech Republic. The research aimed to examine the current level of these competencies on the sample of top managers of those enterprises. The chosen topic is topic of current importance due the competency development for enhancing the managerial performance. The thesis elaboration was based on the detailed literature review of national and international publications in the respected scientific journals, and on the in-depth analyses conducted through the primary researches. The main objective of the dissertation thesis was to detect the competency level of top managers in the small manufacturing enterprises in the context of business management and to identify the key variables influencing the discovered competency level and on the basis of research findings provide recommendations for further competency development. The main objective was supported with four partial objectives and five research hypotheses. On the basis of results of executed pilot research on managerial competencies the model of managerial competencies was established, and further verified in the author’s primary research. Within the data analysis and data evaluation, the competency level was formed. The dependences of competencies on examined variables were tested empirically. Those variables were sex, length of current and total practice, age, ownership and education. The aggregated research results were compared with the literature review and based on this comparison, the recommendations for further managerial competency level improvement were provided. The conclusions and further research aims form the integral part of the dissertation thesis.
Applying Diversity Management Concept in the Field of Human Resource Management
Senichev, Valery ; Blažek, Ladislav (referee) ; Tomšík, Pavel (referee) ; Szarková, Miroslava (referee) ; Konečná, Zdeňka (advisor)
The presented Ph.D. thesis deals with the topic of Diversity management and its application into the area of Human Resourse Management. The main goal of the thesis is to survey the impact of diversity on the effective team operation in selected organizations in the Czech Republic. The aim of the thesis is thus to identify factors that influence the team effectiveness.The investigated teams operate in selected companies in the Czech Republic The Ph.D. thesis is divided into two parts: the theoretical part and the empirical part. The aim of the theoretical part is to provide a summary of personnel work in organizations with a focus on Human Resource Management at organizational and team´s level. Modern trends are also introduced: diversity management, talent management etc.The second part of the theoretical part is dedicated to diversity and diversity management, diversity classification, the structure of diversity management, functioning in teams, diverse teams and measuring the influence of diversity on team effectiveness. In the end of the theoretical part a summary of key research results is presented. A dictionary of key terms is also created as a part the presented thesis. In the empirical part an analysis of the research results gained by making pilot researches and main research are presented.The research was focused on studying the effectiveness of diverse teams in organizations mainly from the following sectors: Finance a Insurance, IT, Information and communication and Education. The research sample in the main research consisted of 98 team leaders.The gathered data were processed using descriptive and explorative statistics (nonparametric tests: Spearman's rank correlation coefficient, the Mann – Whitney U test and The Kruskal – Wallis Test). A qualitative analysis was used in the analysis of chosen items.The main results of the research is the following: 1.a slightly positive correlation was detected between gender diversity and handling project or work deadlines. 2.a positive correlation was found between informational diversity and goals or specific task/assignment achievement. 3. a slightly positive correlation was detected between the informational diversity and handling project or work deadlines. In teams with a focus on Human Resource Management a middle level of gender diversity was found, whereas in project teams the informational diversity is on a high level. Marketing teams have a lower level of information diversity. The same results is for teams with a focus on Management of academic projects/programs. No relationship was detected between the team effectiveness and the team size. The same negative results were found for the organizational size and the rate of occurence of age, gender or informational diversity.The qualitative analysis concluded that age diversity is linked with a situation of mixing different perspectives and experience in teams; gender diversity could have a positive influence on socio – psychological dynamics in a team and be efficient for client management. Informational diversity was mentioned as a factor of improving the problem-solving process and project effectiveness. Respondents were asked to define the traits/factors of a high – performing teams. Proportions in gender: 50:50, proportional representation of experienced and not so experienced peers in teams. The role of the manager is to unite the team, to support team members´potential, team cooperation with a goal to fulfil the task.
A study on the activity of α-tomatine and newly synthetized derivatives of benzo[c]fluorene
Suchá, Lenka ; Tomšík, Pavel (advisor) ; Pejchal, Jaroslav (referee) ; Poučková, Pavla (referee)
Many of anticancer drugs are of natural origin. Plants from the Solanaceae family contain various steroidal glycoalkaloids that are toxic to cancer cells. The aim of the first part of this work was to evaluate the potential anticancer effect of α-tomatine - a steroidal glycoalkaloid from Solanaceae plant family. The second part of this work was focused on the anticancer research of newly synthetized derivatives of benzo[c]fluorene. Benfluron, one of the derivatives, was reported 30 years ago to have anticancer effects in vitro and in vivo almost. Tomatine inhibited the proliferation and viability of MCF-7 cells. In this cancer cell line treated with tomatine, no DNA damage, no changes in p53 and p21WAF1/CIP1 protein levels, neither the induction of apoptosis was demonstrated. However, the decrease in ATP levels was found. New synthetized derivatives of benfluron and dimefluron caused higher cytotoxic effect in the different cancer cell lines compared with their original compounds. On the other hand, these derivatives did not caused higher tumour growth inhibition when compared with their original compounds in in vivo studies. Benfluron and hydrazone of dimeflurone prolonged the survival of mice with inoculated solid form of Ehrlich tumour. In this work, we demontrated that tomatine did not induce apoptosis...
Applying Diversity Management Concept in the Field of Human Resource Management
Senichev, Valery ; Blažek, Ladislav (referee) ; Tomšík, Pavel (referee) ; Szarková, Miroslava (referee) ; Konečná, Zdeňka (advisor)
The presented Ph.D. thesis deals with the topic of Diversity management and its application into the area of Human Resourse Management. The main goal of the thesis is to survey the impact of diversity on the effective team operation in selected organizations in the Czech Republic. The aim of the thesis is thus to identify factors that influence the team effectiveness.The investigated teams operate in selected companies in the Czech Republic The Ph.D. thesis is divided into two parts: the theoretical part and the empirical part. The aim of the theoretical part is to provide a summary of personnel work in organizations with a focus on Human Resource Management at organizational and team´s level. Modern trends are also introduced: diversity management, talent management etc.The second part of the theoretical part is dedicated to diversity and diversity management, diversity classification, the structure of diversity management, functioning in teams, diverse teams and measuring the influence of diversity on team effectiveness. In the end of the theoretical part a summary of key research results is presented. A dictionary of key terms is also created as a part the presented thesis. In the empirical part an analysis of the research results gained by making pilot researches and main research are presented.The research was focused on studying the effectiveness of diverse teams in organizations mainly from the following sectors: Finance a Insurance, IT, Information and communication and Education. The research sample in the main research consisted of 98 team leaders.The gathered data were processed using descriptive and explorative statistics (nonparametric tests: Spearman's rank correlation coefficient, the Mann – Whitney U test and The Kruskal – Wallis Test). A qualitative analysis was used in the analysis of chosen items.The main results of the research is the following: 1.a slightly positive correlation was detected between gender diversity and handling project or work deadlines. 2.a positive correlation was found between informational diversity and goals or specific task/assignment achievement. 3. a slightly positive correlation was detected between the informational diversity and handling project or work deadlines. In teams with a focus on Human Resource Management a middle level of gender diversity was found, whereas in project teams the informational diversity is on a high level. Marketing teams have a lower level of information diversity. The same results is for teams with a focus on Management of academic projects/programs. No relationship was detected between the team effectiveness and the team size. The same negative results were found for the organizational size and the rate of occurence of age, gender or informational diversity.The qualitative analysis concluded that age diversity is linked with a situation of mixing different perspectives and experience in teams; gender diversity could have a positive influence on socio – psychological dynamics in a team and be efficient for client management. Informational diversity was mentioned as a factor of improving the problem-solving process and project effectiveness. Respondents were asked to define the traits/factors of a high – performing teams. Proportions in gender: 50:50, proportional representation of experienced and not so experienced peers in teams. The role of the manager is to unite the team, to support team members´potential, team cooperation with a goal to fulfil the task.
A study on the activity of α-tomatine and newly synthetized derivatives of benzo[c]fluorene
Suchá, Lenka ; Tomšík, Pavel (advisor) ; Pejchal, Jaroslav (referee) ; Poučková, Pavla (referee)
Many of anticancer drugs are of natural origin. Plants from the Solanaceae family contain various steroidal glycoalkaloids that are toxic to cancer cells. The aim of the first part of this work was to evaluate the potential anticancer effect of α-tomatine - a steroidal glycoalkaloid from Solanaceae plant family. The second part of this work was focused on the anticancer research of newly synthetized derivatives of benzo[c]fluorene. Benfluron, one of the derivatives, was reported 30 years ago to have anticancer effects in vitro and in vivo almost. Tomatine inhibited the proliferation and viability of MCF-7 cells. In this cancer cell line treated with tomatine, no DNA damage, no changes in p53 and p21WAF1/CIP1 protein levels, neither the induction of apoptosis was demonstrated. However, the decrease in ATP levels was found. New synthetized derivatives of benfluron and dimefluron caused higher cytotoxic effect in the different cancer cell lines compared with their original compounds. On the other hand, these derivatives did not caused higher tumour growth inhibition when compared with their original compounds in in vivo studies. Benfluron and hydrazone of dimeflurone prolonged the survival of mice with inoculated solid form of Ehrlich tumour. In this work, we demontrated that tomatine did not induce apoptosis...
Managerial Competencies in Small Enterprises
Novák, Petr ; Szarková, Miroslava (referee) ; Mohelská, Hana (referee) ; Tomšík, Pavel (referee) ; Putnová, Anna (advisor)
The dissertation thesis dealt with the managerial competencies in the small manufacturing enterprises in the Czech Republic. The research aimed to examine the current level of these competencies on the sample of top managers of those enterprises. The chosen topic is topic of current importance due the competency development for enhancing the managerial performance. The thesis elaboration was based on the detailed literature review of national and international publications in the respected scientific journals, and on the in-depth analyses conducted through the primary researches. The main objective of the dissertation thesis was to detect the competency level of top managers in the small manufacturing enterprises in the context of business management and to identify the key variables influencing the discovered competency level and on the basis of research findings provide recommendations for further competency development. The main objective was supported with four partial objectives and five research hypotheses. On the basis of results of executed pilot research on managerial competencies the model of managerial competencies was established, and further verified in the author’s primary research. Within the data analysis and data evaluation, the competency level was formed. The dependences of competencies on examined variables were tested empirically. Those variables were sex, length of current and total practice, age, ownership and education. The aggregated research results were compared with the literature review and based on this comparison, the recommendations for further managerial competency level improvement were provided. The conclusions and further research aims form the integral part of the dissertation thesis.

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