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Comparative analysis of the effect on disease-modifying drugs and biological therapy in functional ability in patients with rheumatoid arthritis.
Sýkorová, Veronika ; Vomáčková, Helena (advisor) ; Nováková, Tereza (referee)
Autor: Bc. Veronika Sýkorová Title: Comparative analysis of the effect on disease-modifying drugs and biological therapy in functional ability in patients with rheumatoid arthritis. Objective: The aim of the thesis is to compare the effect of disease-modifying drugs and biological therapy on quality of life using the disability index, which is achieved by evaluating the HAQ, grip strength the small muscles of the hand, which is tested a hand dynamometer and standing stability, which is detected by measuring on stabilometric platform. Methods: This is a pilot study using subjective and objective examination. Stabilometric and dynamometric examination and the Czech version of the Stanford Health Assessment Questionnaire validated by Rheumatology Institute in Prague 2010 were used to the analysis. Evaluation of the collected data was done using two-way analysis of variance with repetition. Results: Biological therapy and disease-modifying antirheumatic drugs have significant impact on quality of life, the strength of the small muscles of the hand and standing stability in patients with rheumatoid arthritis. Disease-modifying antirheumatic drugs have reached significant results than the biological therapy in quality of life, forces the small muscles of the right hand and standing stability. Biological...
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Case study of physiotherapy treatment of a patient with Juvenile Rheumatoid Arthritis
Sýkorová, Veronika ; Šlaisová, Markéta (advisor) ; Jarošová, Hana (referee)
Title of bachelor's thesis Case Study of physiotherapy treatment of patient with Juvenile Rheumatoid Arthritis Summary The goal of my work is to characterize the issue of the juvenile idiopathic arthritis. In the first more theoretical part, I specifically describe the above mentioned disease and make a general distinction among the rheumatic diseases. The second part elaborates on a special case report of a patient being diagnosed with the juvenile idiopathic arthritis, which I had been working on during the four-week work experience at the Rheumatology Institute in Prague. This section includes the input and output kinesiology analysis, short- and long-term therapeutic plan, design/proposal and description of particular treatment therapies. Key words: rheumatology, physical therapy, juvenile rheumatoid arthritis, case report
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Diet quality impact on growth and survival of freshwater zooplankton species
Sýkorová, Veronika ; Sacherová, Veronika (advisor) ; Nedbalová, Linda (referee)
Food quality has a significant influence on freshwater zooplankon. It influences its growth rate and development generally. By quality we understand a certain stoichiometric ratio of the main biogenic elements (carbon, nitrogen, phosphorus) in the biomass of food. Ecological stechiometry is helping to understand the balance of chemical elements in ecological interactions and processes. Freshwater zooplankton consists mostly of two groups of organisms: rotifers (Rotifera) and crustaceans (Crustacea) - cladocerans (Cladocera) and copepods (Copepoda). Each of this groups requires different quality of food. Most of filtering cladocerans are fast- growing organisms, which need a phosphorus-rich food for their fast development (small C:P ratio in food) and vice versa for most of the copepods. The food offered is not always ideal for all members of zooplankton, that is why various pre- and post- absorptional mechanisms developed to help them to cope with unsuitable food. The ability to survive unvafourable conditions is closely linked to the zoolpankton's reactions to unsuitable C:N:P ratio in its food. The C:N:P ratio in food of zooplankton also influences the species distribution in water bodies. Key words: stoichiometry, food quality, zooplankton
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Comparative analysis of the effect on disease-modifying drugs and biological therapy in functional ability in patients with rheumatoid arthritis.
Sýkorová, Veronika ; Vomáčková, Helena (advisor) ; Nováková, Tereza (referee)
Autor: Bc. Veronika Sýkorová Title: Comparative analysis of the effect on disease-modifying drugs and biological therapy in functional ability in patients with rheumatoid arthritis. Objective: The aim of the thesis is to compare the effect of disease-modifying drugs and biological therapy on quality of life using the disability index, which is achieved by evaluating the HAQ, grip strength the small muscles of the hand, which is tested a hand dynamometer and standing stability, which is detected by measuring on stabilometric platform. Methods: This is a pilot study using subjective and objective examination. Stabilometric and dynamometric examination and the Czech version of the Stanford Health Assessment Questionnaire validated by Rheumatology Institute in Prague 2010 were used to the analysis. Evaluation of the collected data was done using two-way analysis of variance with repetition. Results: Biological therapy and disease-modifying antirheumatic drugs have significant impact on quality of life, the strength of the small muscles of the hand and standing stability in patients with rheumatoid arthritis. Disease-modifying antirheumatic drugs have reached significant results than the biological therapy in quality of life, forces the small muscles of the right hand and standing stability. Biological...
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Food quality impact on growth and survival of Daphnia longispina (Crustacea: Cladocera)
Sýkorová, Veronika ; Sacherová, Veronika (advisor) ; Macháček, Jiří (referee)
This thesis focuses on ecological processes among plankton organisms. It especially questions the influence of food quality on growth and survival of freshwater plankton. I focused on the influence of various ratios of nitrogen and phosphorus in available food. I am also interested in finding out the food requirements of chosen consumer Daphnia longispina. Within this broad topic, I specify a question, whether various quality and quantity of food influences the life history parameters of the species Daphnia longispina and whether the absence of common species of Cladoceran Daphnia longispina in Plešné Lake is caused by unsuitable quality of food. I have bred Daphnia longispina in laboratory conditions for two years. I fed it by algae Monoraphidium dybowskii isolated from Plešné Lake and grown in two media P-limited (C:P 1174), P-unlimited (C:P 290) and three concentration (1,2, 4 mg C/L). Cladocerans fed by food from medium that had a C:N:P ratio approximately the same as can be found in Plešné Lake (C:P 1174) lived for a singificantly shorter period of time and during the experiment they did not reproduce even in the case with the largest amount of food (4 mg C/L). This is a possible reason why Daphnia longispina did not return to Plešné Lake after the period of strong acidification, climax of...
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Diet quality impact on growth and survival of freshwater zooplankton species
Sýkorová, Veronika ; Sacherová, Veronika (advisor) ; Nedbalová, Linda (referee)
Food quality has a significant influence on freshwater zooplankon. It influences its growth rate and development generally. By quality we understand a certain stoichiometric ratio of the main biogenic elements (carbon, nitrogen, phosphorus) in the biomass of food. Ecological stechiometry is helping to understand the balance of chemical elements in ecological interactions and processes. Freshwater zooplankton consists mostly of two groups of organisms: rotifers (Rotifera) and crustaceans (Crustacea) - cladocerans (Cladocera) and copepods (Copepoda). Each of this groups requires different quality of food. Most of filtering cladocerans are fast- growing organisms, which need a phosphorus-rich food for their fast development (small C:P ratio in food) and vice versa for most of the copepods. The food offered is not always ideal for all members of zooplankton, that is why various pre- and post- absorptional mechanisms developed to help them to cope with unsuitable food. The ability to survive unvafourable conditions is closely linked to the zoolpankton's reactions to unsuitable C:N:P ratio in its food. The C:N:P ratio in food of zooplankton also influences the species distribution in water bodies. Key words: stoichiometry, food quality, zooplankton
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Case study of physiotherapy treatment of a patient with Juvenile Rheumatoid Arthritis
Sýkorová, Veronika ; Šlaisová, Markéta (advisor) ; Jarošová, Hana (referee)
Title of bachelor's thesis Case Study of physiotherapy treatment of patient with Juvenile Rheumatoid Arthritis Summary The goal of my work is to characterize the issue of the juvenile idiopathic arthritis. In the first more theoretical part, I specifically describe the above mentioned disease and make a general distinction among the rheumatic diseases. The second part elaborates on a special case report of a patient being diagnosed with the juvenile idiopathic arthritis, which I had been working on during the four-week work experience at the Rheumatology Institute in Prague. This section includes the input and output kinesiology analysis, short- and long-term therapeutic plan, design/proposal and description of particular treatment therapies. Key words: rheumatology, physical therapy, juvenile rheumatoid arthritis, case report
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Data Quality Metrics
Sýkorová, Veronika ; Slánský, David (advisor) ; Pour, Jan (referee)
The aim of the thesis is to prove measurability of the Data Quality which is a relatively subjective measure and thus is difficult to measure. In doing this various aspects of measuring the quality of data are analyzed and a Complex Data Quality Monitoring System is introduced with the aim to provide a concept for measuring/monitoring the overall Data Quality in an organization. The system is built on a metrics hierarchy decomposed into particular detailed metrics, dimensions enabling multidimensional analyses of the metrics, and processes being measured by the metrics. The first part of the thesis (Chapter 2 and Chapter 3) is focused on dealing with Data Quality, i.e. provides various definitions of Data Quality, gives reasoning for the importance of Data Quality in a company, and presents some of the most common tools and solutions that target to managing Data Quality in an organization. The second part of the thesis (Chapter 4 and Chapter 5) builds on the previous part and leads into measuring Data Quality using metrics, i.e. contains definition and purpose of Data Quality Metrics, places them into the multidimensional context (dimensions, hierarchies) and states five possible decompositions of Data Quality metrics into detail. The third part of the thesis (Chapter 6) contains the proposed Complex Data Quality Monitoring System including description of Data Quality Management related dimensions and processes, and most importantly detailed definition of bottom-level metrics used for calculation of the overall Data Quality.
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