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Financing of Business Activities
Pavličková, Martina ; Egressyová, Andrea (referee) ; Ptáček, Roman (advisor)
The bachelor’s thesis deals with the financing of business activities. In my thesis I focused on financing a new working place in the company. Thesis is divided into 3 main sections. The first part focused on the theoretical description of the different types of financing and the types of companies, which finance their business activities, and the theoretical definition of analyzes. The second part deals with individual analyzes aplied into a specific company. The last part contains finding the most apropriate form of financing for business activities.
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Phospholipid metabolism in the formation of structured yeast colonies
Pavlíčková, Martina ; Schierová, Michaela (advisor) ; Heidingsfeld, Olga (referee)
Yeasts in their natural environment form structured colonies. This allows them to better adapt to environmental conditions, but also to more easily resist various types of yeast infection inhibitors. The metabolism of phospholipids is closely related to the morphology of colonies. An important gene involved in phospholipid metabolism is INO1, which encodes inositol-3- phosphate synthase. Expression of the INO1 gene is regulated by the Opi1p negative transcription factor, which also affects a number of other genes for phospholipid metabolism enzymes, is also necessary for the expression of the FLO11 gene, encoding Flo11p, which is essential to the formation of a structured colony. The main aim of my work was to investigate the correlation between colony morphology of a natural strain of Saccharomyces cerevisiae and phospholipid metabolism. I have found that changes in INO1 gene expression and colony morphology are influenced by carbon source, selenate activity and the inhibitor of β-oxidation, 2-bromooctanoic acid. Although the INO1 gene is not essential for cell viability, its deletion or overexpression causes changes in phospholipid metabolism and colony morphology. Selenate and 2-bromooctanoic acid also alter expression of the FLO11 gene, which is reflected in colony structure. Thus, 2-...
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Financing of Business Activities
Pavličková, Martina ; Egressyová, Andrea (referee) ; Ptáček, Roman (advisor)
The bachelor’s thesis deals with the financing of business activities. In my thesis I focused on financing a new working place in the company. Thesis is divided into 3 main sections. The first part focused on the theoretical description of the different types of financing and the types of companies, which finance their business activities, and the theoretical definition of analyzes. The second part deals with individual analyzes aplied into a specific company. The last part contains finding the most apropriate form of financing for business activities.
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House arrest, its execution and control
Pavlíčková, Martina ; Tlapák Navrátilová, Jana (advisor) ; Galovcová, Ingrid (referee)
Summary: House arrest, its execution and control The aim of this thesis is to give a comprehensive summary of the institute of the house arrest, the actual legal regulation of this punishment, to summarize its advantages and disadvantages and to draw attention to the problematic issues with it related. The thesis is divided into eleven chapters, which are divided into other subchapters. The first chapter deals with the general concept of punishment, it's purpose, functions and the general system of penalties. A separate sub-chapter constitutes a imprisoment as a basic "universal" punishment. Because the house arrest is one of the alternative punishments, the second chapter deals with the general regulation of alternative punishment. Alternative punishments closely related with the restorative justice, which is described in third chapter, in particular its aims and the principles on which it is exposed. The following chapters are the core of the thesis to the actual punishment of house arrest. The fourth chapter describe the history of the house arrest and the fifth chapter describe a general information of this sentence. The sub-chapters describe the crimes for which custodial sentences may be imposed and other conditions of house arrest, in particular the obligations of convicted. The transformation of the...
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Conceptual documents in the field of culture and their use in the traditional folk culture of the Zlín Region
Pavlíčková, Martina ; Malcová, Zuzana (advisor) ; Skopová, Věra (referee)
The bachelor thesis aims to find contemporary approaches to support and preservation of traditional and folk culture according to the used strategic and conceptual documents. The theoretical part is devoted to the analysis of the Recommendation of the 25th General Conference of UNESCO on the Safeguarding of Traditional Culture and Folklore from 1989 and, in particular, to the Convention for the Safeguarding of the Intangible Cultural Heritage of 2003, which is based on the Recommendation. Based on these, the Strategy of Improved Care for Traditional Folk Culture in the Czech Republic for the period 2016-2020 was created. According to these documents, in the practical part of the thesis, the cultural legislative documents of the Zlín Region will be analyzed (especially the Conception of the Local Culture Development of the Zlín Region and the Concept of the Development of the Zlín Region Organizations in the Field of Culture for the period 2015-2024) with application to the traditional folk culture of this region.
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Phospholipid metabolism in the formation of structured yeast colonies
Pavlíčková, Martina ; Schierová, Michaela (advisor) ; Heidingsfeld, Olga (referee)
Yeasts in their natural environment form structured colonies. This allows them to better adapt to environmental conditions, but also to more easily resist various types of yeast infection inhibitors. The metabolism of phospholipids is closely related to the morphology of colonies. An important gene involved in phospholipid metabolism is INO1, which encodes inositol-3- phosphate synthase. Expression of the INO1 gene is regulated by the Opi1p negative transcription factor, which also affects a number of other genes for phospholipid metabolism enzymes, is also necessary for the expression of the FLO11 gene, encoding Flo11p, which is essential to the formation of a structured colony. The main aim of my work was to investigate the correlation between colony morphology of a natural strain of Saccharomyces cerevisiae and phospholipid metabolism. I have found that changes in INO1 gene expression and colony morphology are influenced by carbon source, selenate activity and the inhibitor of β-oxidation, 2-bromooctanoic acid. Although the INO1 gene is not essential for cell viability, its deletion or overexpression causes changes in phospholipid metabolism and colony morphology. Selenate and 2-bromooctanoic acid also alter expression of the FLO11 gene, which is reflected in colony structure. Thus, 2-...
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Pleiotropic effects of transcriptional protein Opi1 in Saccharomyces cerevisiae
Pavlíčková, Martina ; Schierová, Michaela (advisor) ; Mašek, Tomáš (referee)
Phospholipid biosynthesis in Sacchromyces cerevisiae is regulated by Ino2p-Ino4p activation complex and Opi1p repressor. The most highly regulated INO1 gene encodes inositol-3- phosphate synthase. This enzyme catalyzes the first step of the metabolic pathway of inositol synthesis. The Ino2p-Ino4p activation complex binds to the promoter of the target genes and interacts with other proteins necessary for activation (Snf1p, SAGA, SWI/SNF, INO80). The Opi1p represses transcription by direct binding to Ino2p and by interaction with other proteins (Sin3p, Cyc8p). The activity of Opi1p protein is mediated by cellular localization and by phosphorylation. The regulation of phospholipids is dependent on the growth phase and on the availability of precursors. Apart from its repressor activity, Opi1p affects mitochondrial metabolism, endoplasmic reticulum stress, cell size, mat formation and invasive growth.
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