Název: Comparison of in vitro tests for measurement of estrogenity of chlorinated compounds and their use in the evaluation of biodegradation of chlorbenzoates by the fungus Panus tigrinus
Autoři: Svobodová, Kateřina ; Covino, S. ; Křesinová, Zdena ; Cajthaml, Tomáš
Typ dokumentu: Příspěvky z konference
Konference/Akce: Odpadové fórum, Milovy (CZ), 2009-04-22 / 2009-04-24
Rok: 2009
Jazyk: eng
Abstrakt: Recently, contamination of the environment by endocrine disruptive compounds, toxicity of these chemicals and their biodegradability are widely studied. This work is focused on estrogenity of chlorinated phenols and chlorbenzoic acids that represent potential degradation products of PCB compounds. Two different yeast bioassays for evaluation of estrogenity based on recombinated strains of Saccharomyces cerevisie were compared in this work. Estrogenic activity of chlorbenzoic acids varied with the chemical structure of chemicals. A mixture of chlorbenzoates (initial concentration 10 ppm) was degraded by a ligninolytic fungus Panus tigrinus in liquid cultures. Chemicals resulting from degradation were tested for their estrogenity, however, results indicated that the test responses were inhibited probably by some compounds present in the fungal culture liquid
Klíčová slova: biodegradation; chlorbenzoates; yeast assay
Číslo projektu: CEZ:AV0Z50200510 (CEP), 2B06156 (CEP)
Poskytovatel projektu: GA MŠk
Zdrojový dokument: Odpadové fórum 2009 - sborník přednášek, ISBN 978-80-02-02108-7

Instituce: Mikrobiologický ústav AV ČR (web)
Informace o dostupnosti dokumentu: Dokument je dostupný v příslušném ústavu Akademie věd ČR.
Původní záznam: http://hdl.handle.net/11104/0005744

Trvalý odkaz NUŠL: http://www.nusl.cz/ntk/nusl-41291


Záznam je zařazen do těchto sbírek:
Věda a výzkum > AV ČR > Mikrobiologický ústav
Konferenční materiály > Příspěvky z konference