Original title: Activation of human RNase L by 5’-C-phosphonate-modified oligoadenylates
Authors: Petrová, Magdalena ; Buděšínský, Miloš ; Zborníková, Eva ; Panova, Natalya ; Novák, Pavel ; Rosenberg, Ivan
Document type: Papers
Conference/Event: Symposium on Chemistry of Nucleic Acid Components /16./, Český Krumlov (CZ), 2014-06-08 / 2014-06-13
Year: 2014
Language: eng
Abstract: Adeno’sine 5’-(S)-C-phosphonate (pCOHX) was prepared as monomer suitable for oligonucleotide synthesis. Modified tetramers pCOHXAAA and pCOHXAApCOHX were assembled on solid phase and evaluated for their ability to activate human RNase L.
Keywords: human RNase L; oligoadenylates
Project no.: GA13-26526S (CEP), GA13-24880S (CEP), TA03010598 (CEP)
Funding provider: GA ČR, GA ČR, GA TA ČR
Host item entry: Chemistry of Nucleic Acid Components. 16th Symposium, ISBN 978-80-86241-50-0

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0234442

Permalink: http://www.nusl.cz/ntk/nusl-174771


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers