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Bar transverse handling and transfering devices
Horký, Pavel ; Marek, Tomáš (referee) ; Knoflíček, Radek (advisor)
This bachelors thesis deals with the design of bar transverse handling and transferring device. In this thesis are described firstly fundamental principles of currently used mechanisms and secondly the components used to design mechanisms. In the last part is described the calculation of the main shaft, bearings and the engine. Attached are drawings of the designed device.
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Design of chain transfer with creating a batch of bars
Horký, Pavel ; Omes, Jiří (referee) ; Knoflíček, Radek (advisor)
The diploma thesis deals with the design of mechanism for manipulation with bars and creating a batch of square steel bars. In intoduction of this thesis is describtion of principle of curent mechanisms. In following chapters are described the most important parts of new mechanism and their design. In final sections are risk analysis and financial evaluation.
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The Proposal of Communication Mix of the Company Autopark Brno a.s.
Šmerek, Jakub ; Horký, Pavel (referee) ; Navrátilová, Ludmila (advisor)
The bachelor thesis is primarily describing communication mix of the company Autopark Brno a. s., that is dealing with Kia cars selling. The thesis is divided into three parts. First one is a theoretical part about marketing communication, which is used as base of analytical part. Next part contains information about the company’s marketing communication, its SWOT analysis, and description of each component of its communication mix. The last part describes a suggestion for the propagation improvement. This should be leading to bigger company image awareness, so it should raise the sells too.
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Modbus / TCP interface for crossroad model control
Horký, Pavel ; Štohl, Radek (referee) ; Macho, Tomáš (advisor)
In this work you will find summary of information regarding the management of intersections. Furthermore, the types of industrial communications with specification and more detailed analysis for the Modbus TCP protocol. The second part is the creation of the final product. It addresses the issue of requirements for the device and the way in which they were resolved.
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Analysis of drug administration by nurses in health facility II
Bančíková, Natalie ; Malý, Josef (advisor) ; Horký, Pavel (referee)
Analysis of drug administration by nurses in a health facility II Author: Natalie Blizňáková Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Ondřej Tesař Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aim: Medication errors are one of the main causes of adverse events that can lead to damage to health or death of the patient. The aim of this work was to analyze the administration of drugs by nurses to patients hospitalized in one health facility providing inpatient care in the South Bohemian region with emphasis on medication errors and their prevention. Methodology: This diploma thesis is part of a long-term observation-intervention project, which takes place in the years 2020-2023. The surgical, internal medicine and aftercare departments were observed. Data collection for this work took place in the form of direct observation by a trained team of pharmacists and nurses, from June 28 to July 1 and from August 23 to August 26, 2021, for three consecutive days. The following data were collected: patient data (e.g., age; gender; all drugs used), data on the nurse administering the drugs (e.g., length of practice and education) and data on the actual administration of drugs (e.g., method of patient identification; nurse...
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Analysis of the Drug Related Problems in Facilities for Seniors I.
Duchoňová, Veronika ; Malý, Josef (advisor) ; Horký, Pavel (referee)
Analysis of the Drug Related Problems in Facilities for Seniors I. Author: Veronika Duchoňová1 Tutor: Josef Malý1 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aim: The aim of the thesis was to revise the medical documentation in the aftercare health facility, to classify the identified drug related problems (DRP) and to describe the chosen DRP by the SAZE principals. Methodology: The data collection for this thesis took place in ONLP in the time period from the 27th of August to the 30th of August 2019. The aim of the auditors was a revision of phamacotherapy of all 76 patients. A complete electronic and printed medical documentation was provided. The DRP were identified based on the information about a patient and described by the SAZE principals. The DRP were reported in the electronic database according to the modified PCNE classification V5.01. All obtained data was exported to the Microsoft Office Excel in the form of tables and processed by freqency analysis. Six case studies with the detailed description of the patient and the pharmacist's analysis by the SAZE principals were demonstrated. The conclusion of the audit was presented to doctors and the DRP were discussed at educational seminar. Results: From total of 76...
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Pulse Check in Pharmacies I
Frnková, Michaela ; Malá, Kateřina (advisor) ; Horký, Pavel (referee)
Pulse check in pharmacies I Author: Michaela Frnková Supervisor: PharmDr. Kateřina Malá, Ph.D. Consultant: PharmDr. Anna Rejmanová, Ph.D. De artment o ocial an linical Pharmac , Fac lt o Pharmac in ra ec Králov , harle University Introduction: Atrial fibrillation is one of the most common supraventricular disorders of the heart rhythm. Unless properly treated, it leads to higher mortality and morbidity rates. Early detection of such fibrillation, which is often asymptomatic, may prevent further associated complications, especially ischemic stroke, and a sudden cardiac death. Aim: The thesis focused on the feasibility of involving pharmacists in the screening of the patients with heart rhythm disorders. Further increase awareness of the possibilities and meaning of monitoring heart rhythm disorders in pharmacies and ensure that patients can verify their own heart rate at home. Methods: The heart rhythm measurements were carried within four weeks (11/2017; 11/2018; 6/2019; 12/2019), during the global health initiative "Know o r l e". Mea ring took place at the pharmacy in Pardubice; the pharmacy offers individual consultations to patients. Participation in the screening for the atrial fibrillation was offered to all incoming pharmacy persons who were older than 40 years and without chronic...
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Analysis of drug-related problems in a healthcare facility VIII
Kraušnerová, Kateřina ; Doseděl, Martin (advisor) ; Horký, Pavel (referee)
Analysis of drug-related problems in healthcare facility VIII Author: Kateřina Kraušnerová Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Backgroung: Drug-related problem (DRP) is according to Pharmaceutical Care Network Europe (PCNE) pharmacotherapy related event or circumstance, which actually or potentionaly interfer with a terapeutic purpose. Pharmacists tend to be part of multidisciplinar teams, they help with decisions concerning therapy of the patient, monitoring, participating in the detection of DRPs and by that helping increase effect and safety of pharmacotherapy. Aim: The aim of the theoretical part of this thesis is to cteate summary of DRPs which occurs in antidepressant drug group, ATC N06A, and classify these problems using PCNE V5.01 classification. The aim of the practical part of this thesis is to detect DRPs in healthcare facility, classify these DRPs using PCNE V5.01 classification and asses their relevance and acceptance of interventions made by clinical pharmacist. Methodology: The data were collected since February 7th to March 7th 2022 at hospital in the Czech republic. In total it was collected data from 68 patients. Source of DRPs, their relevance and suggested...
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Biologic drug (biologics) Consumption in Czech Republic II
Farkašová, Veronika ; Horký, Pavel (advisor) ; Doseděl, Martin (referee)
Consumption of biologic drugs (biologics) in the Czech Republic Author: Veronika Farkašová Supervisor: doc. PharmDr. Jozef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction: Biological treatment is modern alternative to chemotherapeutics especially in patients with difficult-to-treat diseases of autoimmune origin, as well as patients with other diseases as is cancer. They are heavily used in oncology for their wide range of indications. They are used as a monotherapy as well as in combination with traditional chemotherapy. Use of biological treatment can reduce the amount of treatment cycles of chemotherapy and reduce unwanted adverse effects. Objective: The aim of the diploma theasis was to analyze the consumption of biologigal treatment rituximab, bevacizumab, cetuximab and alemtuzumab. Methods: A retrospective analysis of the consumption of biosimilars rituximab, bevacizumab, cetuximab and alemtuzumab was performed from 1. 1. 2010 to 31. 12. 2020. The selection of specific biosimilars was made on the basis of their wide indication spectrum. Consumption data were obtained from the database of the State Institute for Drug Control (SÚKL). Descriptive statistics were used for the analysis. Consumption, given in the number...
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Antidepressant (SARI, NDRI, RIMA) Consumption in Czech Republic
Bucková, Veronika ; Horký, Pavel (advisor) ; Ťupová, Lenka (referee)
Antidepressant (SARI, NDRI, RIMA) Consumption in Czech Republic Charles University Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Author: Veronika Bucková Supervisor: PharmDr. Pavel Horký, Ph.D. Antidepressants are drugs used mainly to treat pathologically low mood and anxiety disorders. The antidepressants focused in this work from the SARI, NDRI and RIMA groups are also used in the treatment of insomnia, smoking cessation, as support in weight reduction and in some psychogenic sexual dysfunctions. The goal of this work is to analyze the consumption of antidepressants from the SARI, NDRI and RIMA groups in Czech Republic. The data for this work were obtained from the database of the State Institute for Drug Control on the basis of mandatory reporting of the volume of drugs supplied by distributors to pharmacies and other medical facilities. Consumption was monitored in the period from 1.1.2008 to 31.12.2020. The DUR type methodology was used and consumption was expressed in the number of defined daily doses per thousand inhabitants per day (DID). The results confirm the rising trend of antidepressant consumption only in the case of trazodone (SARI), whose consumption increased 3.8 times compared to 2008. The reason for this growth is the use of trazodone as an...
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