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Program EATS as an alternative in teaching English language at primary school
Chytilová, Anna ; Voda, Jan (advisor) ; Stará, Jana (referee)
This thesis is about an inovative program in teaching English language called EATS. The goal was to find out the effectivness of this program on the basis of repeated observations, didactic testing and interview. In the theoretical part the position of English language in the curricular documents is discussed. Then there is the description of the communicative approach to the language learning which is very useful in nowadays globalised society.The important role of the native speaker is emphasized because he brings the authentic element into the education process and gives pupils good language model. Also the early education in foreign languages is part of this work. Integrated language learning is described on the ilustration of CLIL and its alternative which could be called "language preparation". The aim was to show an example of a good practice which could inspire someone.
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Myocardial phospholipases A2 and oxidative stress
Závišková, Kristýna ; Míčová, Petra (advisor) ; Chytilová, Anna (referee)
Heart and vascular diseases, in which oxidative stress plays an important role, are the most frequent cause of death in developed countries. Therefore today's researches focus on clarifying signaling pathway and their components that operates in these processes. One of the possible key factors can be phospholipases A2. These enzymes hydrolyze unsaturated fatty acids from C2 position on phospholipids, which easily subject to the oxidative modification due to their double bonds. There are five groups: the secreted, the cytosolic, the calcium independent, the platelet-activating factor acetylhydrolases and the lysosomal phospholipases A2. They differ in the requirement for calcium ions for its activity, molecular weight, position of disulfide bonds and amino acids sequences in the active site. Their main importance is to keep the stability and integrity of cell membranes and produce lipid signaling molecules (free fatty acids, lysophospholipids, eicosanoids). The phospholipases A2 play a dual role during oxidative stress in myocardium. First, they have a positive effect by protecting membranes against oxidative stress due to their higher affinity for removal of peroxidized fatty acids from membrane phospholipids. On the other hand, the phospholipases A2 can also cause destructive effects during...
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Aesthetic aspects of photography : Photographic style as a problem for R. Scruton's theory
Chytilová, Anna ; Kulka, Tomáš (advisor) ; Kubalík, Štěpán (referee)
Present BA thesis aims to discuss aesthetic aspects of photography, especially in relation to Roger Scruoton's sceptical theory of photography from his article Photography and Representation in which he calls into question artistic capabilities of this medium. His overall stance holds that photography is not capable of artistic representation as other art media. His opinion is based predominantly on the causality and mechanical character of photography and first part of the thesis will consist of interpretation of his view. The objective of further study is to bring his views into critical light, and then to present some arguments to argue for possibility of individual photographic style, which is doubted in Scroton's theory. Study aims show forth basic aeshetic aspects of photography in its own terms as a specific representational medium and then discuss photographic style on this basis. Argumentation on style will be supported also by particular examples of photographic artworks that show aspects of individual style and by relevant theories, namely N. Goodman's article Status of Style from his work Ways of Worldmaking.
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The role of TNF-alpha and IL-10 in cardioprotective effect of chronic hypoxia
Chytilová, Anna ; Bezouška, Karel (advisor) ; Hloušková, Patricie (referee)
The aim of the present study was to find out whether adaption to chronic hypoxia affects the expresion of TNF-α and IL-10 in rat myocardium. TNF-α is a proinflammatory cytokine, which amplifies inflammatory reaction, while IL-10 has opposite antiinflammatory effect. We also measured concentration of nitrotyrosine as a marker of nitrosative stress. We used male Wistar rats divided into four groups: 1) normoxic controls; 2) exposed to continous normobaric hypoxia (10% O2) for three days or 3) for three weeks and 4) exposed to intermittent normobaric hypoxia (10% O2) for three weeks with one hour daily reoxygenation. Cytosolic and membrane proteins (cytosolic and particulate fractions) were obtained from the left ventricle, right ventricle and interventricular septum. Concentrations of TNF-α and IL-10 in both fractions were measured by ELISA. Continous hypoxia increased TNF-α production in particulate fractions from all ventricular parts and decreased the ratio of IL-10/TNF-α in particulate and cytosolic fractions. Intermittent hypoxia redistributed TNF-α from cytosol into the particulate fraction and prevented the drop of IL-10/TNF-α ratio in the cytosolic fraction. The highest concentration of nitrotyrosine was found in the particulate fraction from the right ventricle after three days of hypoxia....
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Aesthetic aspects of photography : Photographic style as a problem for R. Scruton's theory
Chytilová, Anna ; Kulka, Tomáš (advisor) ; Kubalík, Štěpán (referee)
Present BA thesis aims to discuss aesthetic aspects of photography, especially in relation to Roger Scruoton's sceptical theory of photography from his article Photography and Representation in which he calls into question artistic capabilities of this medium. His overall stance holds that photography is not capable of artistic representation as other art media. His opinion is based predominantly on the causality and mechanical character of photography and first part of the thesis will consist of interpretation of his view. The objective of further study is to bring his views into critical light, and then to present some arguments to argue for possibility of individual photographic style, which is doubted in Scroton's theory. Study aims show forth basic aeshetic aspects of photography in its own terms as a specific representational medium and then discuss photographic style on this basis. Argumentation on style will be supported also by particular examples of photographic artworks that show aspects of individual style and by relevant theories, namely N. Goodman's article Status of Style from his work Ways of Worldmaking.
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Program EATS as an alternative in teaching English language at primary school
Chytilová, Anna ; Voda, Jan (advisor) ; Stará, Jana (referee)
This thesis is about an inovative program in teaching English language called EATS. The goal was to find out the effectivness of this program on the basis of repeated observations, didactic testing and interview. In the theoretical part the position of English language in the curricular documents is discussed. Then there is the description of the communicative approach to the language learning which is very useful in nowadays globalised society.The important role of the native speaker is emphasized because he brings the authentic element into the education process and gives pupils good language model. Also the early education in foreign languages is part of this work. Integrated language learning is described on the ilustration of CLIL and its alternative which could be called "language preparation". The aim was to show an example of a good practice which could inspire someone.
|
|
|
Myocardial phospholipases A2 and oxidative stress
Závišková, Kristýna ; Míčová, Petra (advisor) ; Chytilová, Anna (referee)
Heart and vascular diseases, in which oxidative stress plays an important role, are the most frequent cause of death in developed countries. Therefore today's researches focus on clarifying signaling pathway and their components that operates in these processes. One of the possible key factors can be phospholipases A2. These enzymes hydrolyze unsaturated fatty acids from C2 position on phospholipids, which easily subject to the oxidative modification due to their double bonds. There are five groups: the secreted, the cytosolic, the calcium independent, the platelet-activating factor acetylhydrolases and the lysosomal phospholipases A2. They differ in the requirement for calcium ions for its activity, molecular weight, position of disulfide bonds and amino acids sequences in the active site. Their main importance is to keep the stability and integrity of cell membranes and produce lipid signaling molecules (free fatty acids, lysophospholipids, eicosanoids). The phospholipases A2 play a dual role during oxidative stress in myocardium. First, they have a positive effect by protecting membranes against oxidative stress due to their higher affinity for removal of peroxidized fatty acids from membrane phospholipids. On the other hand, the phospholipases A2 can also cause destructive effects during...
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The role of TNF-alpha and IL-10 in cardioprotective effect of chronic hypoxia
Chytilová, Anna ; Bezouška, Karel (advisor) ; Hloušková, Patricie (referee)
The aim of the present study was to find out whether adaption to chronic hypoxia affects the expresion of TNF-α and IL-10 in rat myocardium. TNF-α is a proinflammatory cytokine, which amplifies inflammatory reaction, while IL-10 has opposite antiinflammatory effect. We also measured concentration of nitrotyrosine as a marker of nitrosative stress. We used male Wistar rats divided into four groups: 1) normoxic controls; 2) exposed to continous normobaric hypoxia (10% O2) for three days or 3) for three weeks and 4) exposed to intermittent normobaric hypoxia (10% O2) for three weeks with one hour daily reoxygenation. Cytosolic and membrane proteins (cytosolic and particulate fractions) were obtained from the left ventricle, right ventricle and interventricular septum. Concentrations of TNF-α and IL-10 in both fractions were measured by ELISA. Continous hypoxia increased TNF-α production in particulate fractions from all ventricular parts and decreased the ratio of IL-10/TNF-α in particulate and cytosolic fractions. Intermittent hypoxia redistributed TNF-α from cytosol into the particulate fraction and prevented the drop of IL-10/TNF-α ratio in the cytosolic fraction. The highest concentration of nitrotyrosine was found in the particulate fraction from the right ventricle after three days of hypoxia....
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