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Employee Satisfaction and Employee Benefits in Selected Company
Turečková, Blanka ; Moštík, Marian (referee) ; Konečný, Štěpán (advisor)
The diploma thesis examines employee satisfaction and employee benefits in a chosen company. It was used a research: asking via a questionaire. The analysis of chosen quality characters has been made in this thesis and the financial impact of the employee benefits has been monitored. On the basis of the results the reseatched situation has been appreciated and there have been proposed possible changes and improvement in the providing of emplayee benefits.

The Study of Aditives and Admixture Influence on High-Performance Concrete Properties
Šiler, Pavel ; Bílek, Vlastimil (referee) ; Brandštetr, Jiří (referee) ; Havlica, Jaromír (advisor)
The aim of this work was to develop the method for the determination of the superperplasticizers (SP) content in the water solution. The method developed was then applied to study the SP adsorption on the individual components used for high-performance concrete and the influence of the temperature and pH values over this adsorption. Furthermore the influence of the water to binder ratio, SP, finely grounded granulated blast furnace slag, fly ash, silica fume, finely ground silica sand and bauxite on the hydration process was studied by means of isoperibolic, isothermal and solution calorimetry. The compressive and flexural strength of most samples used in calorimetric experiments was also determined.

Women quality of life at the climacterium period
Hvězdová, Alexandra ; Vachková, Eva (advisor) ; Zimmerová, Ilona (referee) ; Machalová, Iva (referee)
Author: Alexandra Hvězdová Institution: Ústav sociálního lékařství LF UK v Hradci Králové, Oddělení ošetřovatelství (Nursing Department.) Name of Work: Women Quality of Life at the Climacterium Period Head of Work: Mgr. Eva Vachková Number of Pages: 88, XI Number of Supplements: 9 Number of used titles 38 Year of Defence: 2010 Key Words: hormone replacement therapy, HRT, climacterium, climacterical syndrome, quality of life, menopause, quality of life measurement, MRS, UQOL The Bachelor Thesis is focused on the problems regarding women quality of life at the climacterium period. It detects how climacterium impacts the quality of life in women who use any form of HRT and how climacterium impacts the quality of life in women who do not use any form of HRT. Theoretical part of the Work draws attention in two chapters, besides definition of climacterium, to classification of climacterium, typical symptomatology, diagnostics, treatment and characteristics of disposed women, formulates quality of life on the one hand and possible ways of its measurement on the other hand, both at the general level, as well as at the climacterium period. Empirical part of the Work is based on the research investigation by means of quantitative questioning methods via MRS and UQOL questionnaires, the versions of which...

Chiral Separation of Biologically Important Compounds by High-Performance Separation Methods Using Macrocyclic Antibiotics
Honetschlägerová, Marie
Chiral Separation of Biologically Important Compounds by High-Performance Separation Methods Using Macrocyclic Antibiotics Mgr. Marie Honetschlägerová-Vadinská Abstract The aim of this thesis was to study retention and enantioseparation behavior of selected biologically active compounds by high performance liquid chromatography and capillary liquid chromatography on chiral stationary phases based on glycopeptide antibiotics. The retention and enantioseleparation behavior of selected profen non-steroidal anti- inflammatory drugs (NSAIDs) on a teicoplanin aglycone (TAG) CSP in cLC under various mobile phase compositions was studied. As the chiral capillaries are not commercially available, three capillary columns, packed with TAG stationary phase using the same procedure, were tested to evaluate the repeatability and reproducibility. The cLC results for a set of profen NSAIDs were compared with the HPLC results obtained on the TAG CSPs under the identical separation conditions. The evaluation of the enantioselective performance of two commercially available teicoplanin (T) CSPs with different chiral selector (CS) coverage, i.e., Chirobiotic T and T2 was carried out for three groups of structurally diverse chiral compounds. These compounds were chosen from diverse application fields, namely amino alcohols...

Vplyv pridania zuhoľnatených rastlinných biomás na vermikompostovanie
Gundová, Zsuzsanna
Diploma thesis presents the issue of the impact of the addition of charred plant biomass for vermicomposting. The theoretical section describes the definition of biochar, its production, and application benefits to the soil, and other purposes. In other section, devoted to vermicomposting, there is defined the methodology of domestic vermicomposting. The chapter which is devoted to the own experiment is based on the hypothesis that biochar slows down the process of vermicomposting, reduces odor and emissions produced during the process, and that the combination biochar with vermicompost would be a suitable alternative fertilizer. During the experiment, two bins for vermicomposting were used. Biodegradable waste and biochar were added to the first one, and biodegradable waste were added to the second one. The same type and amount of substrate were added to the bins, and they were placed under certain conditions. The difference was only in the addition of biochar. During the whole process, vermicomposting diversity and the resulting product were studied. Vermicompost was evaluated by the available methods.

The use of xCELLigence in the study of irinotecan effects on the colorectal carcinoma cells in vitro
Vatahová, Lenka ; Szotáková, Barbora (advisor) ; Hašková, Pavlína (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Bc. Lenka Vatahová Supervisor: RNDr. Věra Králová, Ph.D. Title of diploma thesis: The use of xCELLigence in the study of effects of irinotecan in colorectal cancer cells Irinotecan is one of the cytostatic drugs, administered either alone or in combination with 5- fluorouracil (5-FU). Its mechanism of action lies in blocking topoisomerase I resulting in a single-threaded irreparable disruption, which is lethal for the cell. In our study, we examined the use of xCELLigence in the study of effects of irinotecan in colorectal cancer cells. xCELigence, which allows tracking of cells in real time was compared with 2 other methods for determination cell viability, specifically with the WST-1 assay and the Brilliant Blue (BB) assay. Experiments were performed on three cell lines derived from colorectal carcinoma- SW 620, SW 480, and HT 29. The cells were treated with irinotecan in concentration ranges from 5 to 100 µg/ml for 24, 48 and 72 hours. We compared the sensitivity of individual methods and found, that the values differed according to the cell lines. In all cells we calculated the IC 50 value at the time of 72 hours of treatment with irinotecan. And while we have shown that the...

The Analysis of the Triathlon Races at the Olympic Games 2000 and 2004
Pelcr, Pavel ; Horčic, Josef (advisor) ; Suchý, Jiří (referee)
Název: Analýza závodů OH 2000 a OH 2004 v krátkém triatlonu Název v anglickém jazyce: The Analysis ofthe Triathlon Races on the Olympic Games 2000 and 2004. Datum 16.9.2000 se navždy zapsalo zlatým písmem do všech srdcí příznivců tak krásného sportu, jakým je triatlon. V tento den se poprvé v historii tohoto sportu konal závod v krátkém triatlonu v rámci Olympijských her v Sydney v Austrálii. Tímto dnem se triatlon stal s'hrte~ olympijským. -Hlavním tématem této diplomové práce je pokusit se analyzovat výsl~dosažené závodníky v krátkém triatlonu na letních Olympijských -- hrách v Sydney v roce 2000, a také na letních Olympijských hrách v Aténách v roce 2004. V teoretické · části se tato práce zabývá strukturou a determinanty výkonu, dále řízením a strukturou tréninku, prognózami výkonů a metodami analýzy závodů. O analýze výkonů triatlonistů na olympijských hrách bylo napsáno velice málo, ___.-, " proto bych rád p!isp~~~:O )>Iací ke zlepšení tréninkového procesu a přípravy na příští letní Olympijské hry v Pekingu nebo na nejbližší světové soutěže. Cílem~ práce je analyzovat výkony jednotlivých závodníků i skupin a zkoumat techniku běhu u nejlepších sportovců (frekvenci a délku kroku, průměrnou rychlost). K výzkumu a vyjádření výsledků použiji metodu sledování a analýzy videozáznamu a měření frekvence a...

Methylene-bis(phosphonate) derivatives for modification of biomolecules
David, Tomáš ; Lorenc, Miroslav (referee) ; Kubíček, Vojtěch (advisor)
5 Title: Methylene-bis(phosphonate) Derivatives for Modification of Biomolecules Author: Tomáš David Department: Department of Inorganic Chemistry, Faculty of Science Supervisor: RNDr. Vojtěch Kubíček, Ph.D. Supervisor's e-mail address: vvvojta@seznam.cz Abstract The aim of this work was to prepare derivatives of methylen-bis(phosphonic) acid. Thirty compounds (from which 29 are new) were prepared with moderate or good yields. All compounds were fully characterized by NMR and MS. Four new crystal structures were obtained by RTG monocrystal analysis. Derivative containing 4-nitrobenzyl group in the side chain was used for study of bis(phosphonates) adsorption parametres to hydroxyapatite (with quantification by UV-Vis spectroscopy). Several derivatives containing characteristic functi- onal groups (-NH2, -COOH, -NCS) were prepared. These compound are suitable for further derivatization, mainly for conjugation with more complex structures through amide bond or thiourea bridge. Conjugates of building blocks with fluorescent probe (fluorescein and dansyl) were prepared for potencial optical imaging. Further modification of one of the dansyl derivative afforded trifunctional molecule - contating bis(phosphonate) as a vector for a bone tissue, a fluorescent probe for a possible fluorescent imaging and a free...

Methodology of microbiological examination of books and library environment and depositories
Šimůnek, Jan ; Lefnerová, Danuše ; Chaloupková, Jana
Methodology of microbiological examination of books and library environment describes the methods for sampling and their evaluation.
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Metrics Model In Engigeering Company And Its Initial Implementation in Business Intelligence tools
Lukeš, Ondřej ; Novotný, Ota (advisor) ; Krejcar, Petr (referee)
This thesis deals with possibilities of strategic measurement of performance in Czech industrial firm and application of distinguished metrics using Business Intelligence tools. In particular it is a firm called Linde Pohony s.r.o. that produces axes and half axes for forklifts. This thesis is based on contemporary information about strategic performance management and its tools. The main aim of this thesis is to demonstrate possibilities of using Business Intelligence in order to measure key performance metrics. Microsoft's SQL Server 2005 with its Analysis and Integration services are used to prove it. It was necessary to create model of metrics at first. First part of the thesis deals with several ways and methods how to measure firm's performance. Then a proper method to measure performance is chosen. In following chapters ways how Business Intelligence tools can contribute to industrial firms are discussed. Then the real implementation of few metrics is described following with an outline of firm's software architecture. Main contribution of this thesis is particularly in demonstrating power of Business Intelligence tools when they are used along with Balanced Scorecard methodics in small or medium sized Czech industrial firm. Also Linde Pohony s.r.o. can profit from this work -- considering that many administrative tasks are much easier and faster and management has much better view into their firm. Keywords Business Intelligence, industrial firm, Balanced Scorecard, Six Sigma, Theory of Constraints, Strategic performance management, metric